Search Results - "Dodia, C."

Localization, synthesis, and processing of surfactant protein SP-C in rat lung analyzed by epitope-specific antipeptide antibodies by BEERS, M. F, KIM, C. Y, CHANDRA DODIA, FISHER, A. B

“…Surfactant protein C (SP-C), a 3.7-kDa hydrophobic lung-specific protein, is synthesized and secreted by pulmonary type II cells through proteolytic processing…”
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Role of phospholipase A2 enzymes in degradation of dipalmitoylphosphatidylcholine by granular pneumocytes by Fisher, A B, Dodia, C

“…The role of phospholipase A2 (PLA2) enzymes in the degradation of internalized dipalmitoylphospharidylcoline (DPPC) by rat granular pneumocytes was evaluated…”
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Inhibition of lung calcium-independent phospholipase A2 by surfactant protein A by Fisher, A B, Dodia, C, Chander, A

“…The effect of lung surfactant protein A (SP-A) on lung phospholipase A2 (PLA2) activity was investigated. SP-A was purified from bovine surfactant obtained by…”
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A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung by FISHER, A. B, DODIA, C, CHANDER, A, JAIN, M

“…We have shown previously that radiolabelled phosphatidylcholine (PC) in liposomes or natural surfactant is removed from the alveolar space and metabolically…”
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Oxygen-dependent reperfusion injury in the isolated rat lung by Eckenhoff, R G, Dodia, C, Tan, Z, Fisher, A B

“…To further define the relationship between oxygen dependence of lung injury during ischemia and ischemia-reperfusion, we used the isolated, perfused, and…”
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Surfactant protein A regulates uptake of pulmonary surfactant by lung type II cells on microporous membranes by Bates, S R, Dodia, C, Fisher, A B

“…We have investigated the internalization of surfactant by type II cells in primary culture. Previously, we demonstrated that type II cells cultured on…”
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Endothelial cells internalize monoclonal antibody to angiotensin-converting enzyme by Muzykantov, V R, Atochina, E N, Kuo, A, Barnathan, E S, Notarfrancesco, K, Shuman, H, Dodia, C, Fisher, A B

“…We investigated the fate of MAb 9B9, a monoclonal antibody to angiotensin-converting enzyme (ACE), which binds to endothelium both in vitro and in vivo. Using…”
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Role of acidic Ca2+-independent phospholipase A2 in synthesis of lung dipalmitoyl phosphatidylcholine by Fisher, A B, Dodia, C

“…Dipalmitoyl phosphatidylcholine (deltaPC) synthesis by lung epithelium occurs in part by a deacylation/reacylation pathway utilizing phospholipase A2 (PLA2)…”
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Purification and characterization of a calcium-independent acidic phospholipase A2 from rat lung by Wang, R, Dodia, C R, Jain, M K, Fisher, A B

“…Several phospholipase A2 (PLA2) activities have been identified in rat lung homogenate and shown to be important in metabolism of lung phospholipids. One PLA2…”
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Alveolar uptake of lipid and protein components of surfactant by Fisher, A B, Dodia, C, Chander, A

“…We investigated the clearance of radiolabeled natural surfactant from the alveolar space of the isolated perfused rat lung. 3H, 35S-natural surfactant was…”
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A non toxic inhibitor of NADPH oxidase (NOX2) activation attenuates inflammatory lung injury by Fisher⁎, A.B., Lee, I., Dodia, C., Feinstein, S.I., Chatterjee, S.

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Transport of choline by plasma membrane vesicles from lung-derived epithelial cells by Fisher, A B, Dodia, C, Chander, A, Kleinzeller, A

“…A549 cells, a lung epithelium-derived cell line, were used as a model system to study choline transport by granular pneumocytes. Intact cells accumulated free…”
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Na(+)-dependent and Na(+)-independent systems of choline transport by plasma membrane vesicles of A549 cell line by Kleinzeller, A, Dodia, C, Chander, A, Fisher, A B

“…Membrane vesicles of A549 lung cells accumulate choline by two pathways: the Na(+)-independent uphill uptake of choline [Michaelis-Menten constant (Km)…”
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Identification of a cDNA for Ca++-independent phospholipase A2 of lung lamellar bodies/lysosomes by Fisher, A B, Feinstein, S I, Kim, T S, Dodia, C, Skach, W

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Increased surfactant internalization by rat type II cells cultured on microporous membranes by Chinoy, M R, Dodia, C, Fisher, A B

“…We evaluated the influence of various substrata in maintaining internalization of biosynthesized natural surfactant by type II pneumocytes in primary culture…”
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Oxygen-dependent lipid peroxidation during lung ischemia by FISHER, A. B, DODIA, C, ZHONGTUO TAN, AYENE, T, ECKENHOFF, R. G

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ATP and adenosine 3',5'-cyclic monophosphate stimulate the synthesis of surfactant protein A in rat lung by Wali, A, Beers, M F, Dodia, C, Feinstein, S I, Fisher, A B

“…Synthesis and secretion of surfactant protein A (SP-A) were studied in the isolated perfused rat lung using Trans35S-label (approximately 85% methionine, 15%…”
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Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A by Fisher, Aron B, Dodia, Chandra, Feinstein, Sheldon I, Ho, Ye-Shih

“…Lung surfactant dipalmitoylphosphatidylcholine (DPPC) is endocytosed by alveolar epithelial cells and degraded by lysosomal-type phospholipase A₂ (aiPLA₂)…”
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1-Cys Peroxiredoxin, a Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities by Chen, J W, Dodia, C, Feinstein, S I, Jain, M K, Fisher, A B

“…This report provides definitive evidence that the protein 1-Cys peroxiredoxin is a bifunctional (“moonlighting”) enzyme with two distinct active sites. We…”
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cAMP increases synthesis of surfactant-associated protein A by perfused rat lung by Fisher, A B, Arad, I, Dodia, C, Chander, A, Feinstein, S I

“…Synthesis and secretion of surfactant-associated protein were studied in isolated rat lungs perfused with [3H]phenylalanine or [35S]methionine in synthetic…”
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