Search Results - "Dodd, P. R."

Glutamate-mediated transmission, alcohol, and alcoholism by Dodd, Peter R, Beckmann, Alison M, Davidson, Marks S, Wilce, Peter A

“…Glutamate-mediated neurotransmission may be involved in the range of adaptive changes in brain which occur after ethanol administration in laboratory animals,…”
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Association Studies of Neurotransmitter Gene Polymorphisms in Alcoholic Caucasians by FOLEY, P F, LOH, E W, INNES, D J, WILLIAMS, S M, TANNENBERG, A E G, HARPER, C G, DODD, P R

“…: Ethanol enhances mesolimbic/cortical dopamine activity in reward and reinforcement circuits. We investigated the hypothesis that risk for alcoholism may be…”
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Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists by Ali, S F, Onaivi, E S, Dodd, P R, Cadet, J L, Schenk, S, Kuhar, M J, Koob, G F

“…IDARS is an acronym for the International Drug Abuse Research Society. Apart from our scientific and educational purposes, we communicate information to the…”
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Increased TUNEL positive cells in human alcoholic brains by Ikegami, Y., Goodenough, S., Inoue, Y., Dodd, P.R., Wilce, P.A., Matsumoto, I.

“…Alcohol-sensitive neuronal cell loss, which has been reported in the superior frontal cortex and hippocampus, may underlie the pathogenesis of subsequent…”
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Identifying Changes in the Synaptic Proteome of Cirrhotic Alcoholic Superior Frontal Gyrus by Etheridge, N, Mayfield, R D, Harris, R A, Dodd, P R

“…Hepatic complications are a common side-effect of alcoholism. Without the detoxification capabilities of the liver, alcohol misuse induces changes in gene and…”
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Synaptic vesicle transport and synaptic membrane transporter sites in excitatory amino acid nerve terminals in Alzheimer disease by WESTPHALEN, R. I, SCOTT, H. L, DODD, P. R

“…The apparent l-[3H]glutamate uptake rate (v') was measured in synaptic vesicles isolated from cerebral cortex synaptosomes prepared from autopsied Alzheimer…”
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NMDA receptor subunit‐dependent modulation by conantokin‐G and Ala(7)‐conantokin‐G by Ragnarsson, L., Yasuda, T., Lewis, R. J., Dodd, P. R., Adams, D. J.

“…The modulation of recombinant NMDA receptors by conantokin‐G (con‐G) and Ala(7)‐conantokin‐G (Ala(7)‐Con‐G) was investigated in Xenopus oocytes injected with…”
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Ecophysiology of neuronal metabolism in transiently oxygen-depleted environments: Evidence that GABA is accumulated pre-synaptically in the cerebellum by Renshaw, G.M.C., Wise, G., Dodd, P.R.

“…Interactions between coral reef topography, tide cycles, and photoperiod provided selection pressure for adaptive physiological changes in sheltered hypoxic…”
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The effects of alanine-substituted conantokin-G and ifenprodil on the human spermine-activated N-methyl- d-aspartate receptor by Tsai, V.W.-W., Dodd, P.R., Lewis, R.J.

“…We evaluated the effects of Ala-7-conantokin-G (Con-G A7) and ifenprodil on the modulation by spermine of [ 3H]MK801 binding to human cortical membranes. Human…”
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A brain bank for Sri Lanka by De Silva, K R D, Shankar, S K, Mahadevan, A, Dodd, P R

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Variant forms of neuronal glutamate transporter sites in Alzheimer's disease cerebral cortex by Scott, H L, Tannenberg, A E, Dodd, P R

“…The displacement of Na(+)-dependent D-[3H]-aspartate binding by unlabeled D-aspartate or the inhibitors DL-threo-beta-hydroxyaspartate, L-cysteate,…”
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Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex by Lewohl, Joanne M., Wang, Long, Miles, Michael F., Zhang, Li, Dodd, Peter R., Harris, R. Adron

“…Background: Changes in brain gene expression are thought to be responsible for the tolerance, dependence, and neurotoxicity produced by chronic alcohol abuse,…”
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Structure−Activity Studies of Conantokins as Human N-Methyl-d-aspartate Receptor Modulators by Nielsen, Katherine J, Skjærbæk, Niels, Dooley, Michael, Adams, Denise A, Mortensen, Martin, Dodd, Peter R, Craik, David J, Alewood, Paul F, Lewis, Richard J

“…The activities of conantokin-G (con-G), conantokin-T (con-T), and several novel analogues have been studied using polyamine enhancement of [3H]MK-801 binding…”
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Excitotoxic mechanisms in the pathogenesis of dementia by Dodd, P R, Scott, H L, Westphalen, R I

“…Alzheimer disease and related dementias, in common with most major neurological diseases, are characterized by localized brain damage. An abundance of senile…”
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Brain gamma-aminobutyric acid receptor binding is normal in rats with thioacetamide-induced hepatic encephalopathy despite elevated plasma gamma-aminobutyric acid-like activity by Maddison, J E, Dodd, P R, Johnston, G A, Farrell, G C

“…Brain gamma-aminobutyric acid (GABA) receptor density, affinity, and function, and plasma GABA-like activity were determined in rats with acute hepatic…”
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[ 3H]MK-801 binding asymmetry in the IMHV region of dark-reared chicks is reversed by imprinting by Johnston, A.N., Rogers, L.J., Dodd, P.R.

“…Glutamate NMDA-type receptor binding in the intermediate medial hyperstriatum ventrale (IMHV) of dark-hatched chicks is lateralized. This lateralization was…”
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Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves by Dodd, P R, Williams, S H, Gundlach, A L, Harper, P A, Healy, P J, Dennis, J A, Johnston, G A

“…Cerebral cortex tissue was obtained at autopsy from neonatal Poll Hereford calves with clinically confirmed maple syrup urine disease (MSUD), neonatal…”
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Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy by Dodd, Peter R., Kril, Jillian J., Thomas, Gregory J., Watson, Wendy E.J., Johnston, Graham A.R., Harper, Clive G.

“…Superior frontal cortex (SFC) and primary motor cortex tissue was obtained at autopsy from thirteen severe chronic alcoholics with neuropathologically…”
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A rapid method for preparing synaptosomes: comparison, with alternative procedures by Dodd, P R, Hardy, J A, Oakley, A E, Edwardson, J A, Perry, E K, Delaunoy, J P

“…A method for the rapid (1-1.5 h) preparation of nerve ending particles (synaptosomes) from rat cerebral cortex is described. The synaptosome fraction has been…”
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Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease by Hynd, M R, Scott, H L, Dodd, P R

“…We analyzed the expression profile of two NMDAR1 mRNA isoform subsets, NR1(0XX) and NR1(1XX), in discrete regions of human cerebral cortex. The subsets are…”
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