Search Results - "Dodacki, Agnès"
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Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD)
Published in Journal of Alzheimer's disease (01-01-2016)“…The involvement of transporters located at the blood-brain barrier (BBB) has been suggested in the control of cerebral Aβ levels, and thereby in Alzheimer's…”
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Altered cerebral vascular volumes and solute transport at the blood–brain barriers of two transgenic mouse models of Alzheimer's disease
Published in Neuropharmacology (01-06-2014)“…We evaluated the integrity and function of the blood–brain barrier in 3xTg-AD mice aged 3–18 months and in APP/PS1 mice aged 8-months to determine the impacts…”
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Modifications of physical and functional integrity of the blood-brain barrier in an inducible mouse model of neurodegeneration
Published in Neuropharmacology (15-06-2021)“…The inducible p25 overexpression mouse model recapitulate many hallmark features of Alzheimer's disase including progressive neuronal loss, elevated Aβ, tau…”
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Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide
Published in Scientific reports (17-10-2017)“…ABCG4 is an ATP-binding cassette transmembrane protein which has been shown, in vitro , to participate in the cellular efflux of desmosterol and amyloid-β…”
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High brain distribution of a new central nervous system drug candidate despite its P-glycoprotein-mediated efflux at the mouse blood-brain barrier
Published in European journal of pharmaceutical sciences (30-05-2018)“…Efficacy of drugs aimed at treating central nervous system (CNS) disorders rely partly on their ability to cross the cerebral endothelium, also called the…”
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Oatp1a4 and an L-thyroxine-sensitive transporter mediate the mouse blood-brain barrier transport of amyloid-β peptide
Published in Journal of Alzheimer's disease (01-01-2013)“…The influx of amyloid-β peptide (Aβ) across the blood-brain barrier is partly mediated by the receptor for advanced glycation end products (RAGE). But other…”
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MOSAIC: Multi-Omic Spatial Atlas in Cancer, effect on precision oncology
Published in Journal of clinical oncology (01-06-2023)“…e15076 Background: Precision oncology aims to first break diagnoses into biologically distinct subtypes, then pursue personalized therapies for each group of…”
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Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide
Published in Scientific reports (01-12-2017)“…ABCG4 is an ATP-binding cassette transmembrane protein which has been shown, in vitro, to participate in the cellular efflux of desmosterol and amyloid-β…”
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Effect of citrulline on muscle protein turnover in an in vitro model of muscle catabolism
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2020)“…Muscle net catabolism, as seen after severe trauma or sepsis or in postoperative situations, is mediated by hormones (e.g., cortisol) and proinflammatory…”
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