Search Results - "Docter, S H"

Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase by Penning, T D, Chandrakumar, N S, Chen, B B, Chen, H Y, Desai, B N, Djuric, S W, Docter, S H, Gasiecki, A F, Haack, R A, Miyashiro, J M, Russell, M A, Yu, S S, Corley, D G, Durley, R C, Kilpatrick, B F, Parnas, B L, Askonas, L J, Gierse, J K, Harding, E I, Highkin, M K, Kachur, J F, Kim, S H, Krivi, G G, Villani-Price, D, Pyla, E Y, Smith, W G

“…Leukotriene B(4) (LTB(4)) is a pro-inflammatory mediator that has been implicated in the pathogenesis of a number of diseases including inflammatory bowel…”
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The design and synthesis of second generation leukotriene B4 (LTB4) receptor antagonists related to SC-41930 by Penning, T D, Djuric, S W, Docter, S H, Yu, S S, Spangler, D, Anglin, C P, Fretland, D J, Kachur, J F, Keith, R H, Tsai, B S

“…SC-41930, 7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4- dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid, is a selective, orally active, LTB4…”
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Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: impact upon leukotriene B4- and 12(R)-HETE-mediated events by Fretland, D J, Anglin, C P, Bremer, M, Isakson, P, Widomski, D L, Paulson, S K, Docter, S H, Djuric, S W, Penning, T D, Yu, S

“…Leukotriene B4 (LTB4) and 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE] are proinflammatory products of arachidonic acid metabolism that have been implicated…”
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Synthesis of cinnamic acids and related isosteres as potent and selective alpha v beta 3 receptor antagonists by Penning, Thomas D, Russell, Mark A, Chen, Barbara B, Chen, Helen Y, Desai, Bipin N, Docter, Stephen H, Edwards, David J, Gesicki, Glen J, Liang, Chi-Dean, Malecha, James W, Yu, Stella S, Engleman, V Wayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Westlin, Marisa M, Nickols, G Allen

“…We describe a series of conformationally-restricted cinnamic acid peptidomimetics as well as several cinnamic acid isosteres, including 3-phenylpropionic…”
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Antiinflammatory effects of second-generation leukotriene B sub(4) receptor antagonist, SC-53228: Impact upon leukotriene B sub(4)- and 12(R)-HETE-mediated events by Fretland, D J, Anglin, C P, Bremer, M, Isakson, P, Widomski, D L, Paulson, S K, Docter, SH, Djuric, S W, Penning, T D, Yu, S, McKearn, J P

“…Leukotriene B sub(4) (LTB sub(4)) and 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE] are proinflammatory products of arachidonic acid metabolism that have…”
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