Search Results - "Docquier, Mylène"
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Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
Published in Nature communications (27-06-2023)“…Bacteriophage therapy has been suggested as an alternative or complementary strategy for the treatment of multidrug resistant (MDR) bacterial infections. Here,…”
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Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report
Published in The Lancet infectious diseases (01-09-2015)“…Summary Background A detailed description of viral kinetics, duration of virus shedding, and intraviral evolution in different body sites is warranted to…”
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Blood virosphere in febrile Tanzanian children
Published in Emerging microbes & infections (01-01-2021)“…Viral infections are the leading cause of childhood acute febrile illnesses motivating consultation in sub-Saharan Africa. The majority of causal viruses are…”
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Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment
Published in Molecular oncology (01-11-2020)“…Therapeutically guided multidrug optimization (TGMO) technology, composed of experimental testing and in silico modelling, allowed identification of…”
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Detection of dicistroviruses RNA in blood of febrile Tanzanian children
Published in Emerging microbes & infections (01-01-2019)“…Fever is the leading cause of paediatric outpatient consultations in Sub-Saharan Africa. Although most are suspected to be of viral origin, a putative…”
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Astrovirus MLB2, a New Gastroenteric Virus Associated with Meningitis and Disseminated Infection
Published in Emerging infectious diseases (01-05-2016)“…Next-generation sequencing has identified novel astroviruses for which a pathogenic role is not clearly defined. We identified astrovirus MLB2 infection in an…”
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Early markers for myocardial ischemia and sudden cardiac death
Published in International journal of legal medicine (01-09-2016)“…The post-mortem diagnosis of acute myocardial ischemia remains a challenge for both clinical and forensic pathologists. We performed an experimental study…”
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An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice
Published in Molecular endocrinology (Baltimore, Md.) (01-05-2013)“…Testis size and sperm production are directly correlated to the total number of adult Sertoli cells (SCs). Although the establishment of an adequate number of…”
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Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice
Published in PLoS genetics (01-01-2013)“…Mouse sex determination provides an attractive model to study how regulatory genetic networks and signaling pathways control cell specification and cell fate…”
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RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization
Published in BMC genomics (21-03-2011)“…RT-qPCR is a sensitive and increasingly used method for gene expression quantification. To normalize RT-qPCR measurements between samples, most laboratories…”
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Astrovirus MLB2, a New Gastroenteric Virus Associated with Meningitis and Disseminated Infection
Published in Emerging infectious diseases (01-05-2016)“…Next-generation sequencing has identified novel astroviruses for which a pathogenic role is not clearly defined. We identified astrovirus MLB2 infection in an…”
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Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells
Published in International journal of molecular sciences (16-06-2021)“…Resistance in clear cell renal cell carcinoma (ccRCC) against sunitinib is a multifaceted process encompassing numerous molecular aberrations. This induces…”
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Hairy cell leukemia: a specific 17-gene expression signature points to new targets for therapy
Published in Journal of cancer research and clinical oncology (01-08-2022)“…Background Hairy cell leukemia (HCL) is a rare chronic B cell malignancy, characterized by infiltration of bone marrow, blood and spleen by typical “hairy…”
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Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis
Published in The ocular surface (01-01-2021)“…Vernal keratoconjunctivitis (VKC) is a chronic, potentially blinding ocular allergic disease affecting children with uncertain pathogenic mechanisms. To…”
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Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma
Published in Journal of experimental & clinical cancer research (03-04-2023)“…We propose a new approach for designing personalized treatment for colorectal cancer (CRC) patients, by combining ex vivo organoid efficacy testing with…”
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Comparison of Two Experimental Mouse Dry Eye Models through Inflammatory Gene Set Enrichment Analysis Based on a Multiplexed Transcriptomic Approach
Published in International journal of molecular sciences (05-10-2021)“…The goal of this study was to explore the specific signaling pathways related to inflammation in two experimental mouse dry eye (EDE) models. Female C57BL/6…”
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Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1
Published in Frontiers in immunology (15-10-2018)“…In several multicenter clinical trials, HLA-DR was found to be a potential biomarker of dry eye disease (DED)'s severity and prognosis. Given the fact that…”
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Comprehensive human virus screening using high-throughput sequencing with a user-friendly representation of bioinformatics analysis: a pilot study
Published in Journal of clinical microbiology (01-09-2014)“…High-throughput sequencing (HTS) provides the means to analyze clinical specimens in unprecedented molecular detail. While this technology has been…”
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The Maternal Effect Mutation sésame Affects the Formation of the Male Pronucleus in Drosophila melanogaster
Published in Developmental biology (15-06-2000)“…After entering the oocyte and before the formation of the diploid zygote, the sperm nucleus is transformed into a male pronucleus, a process that involves a…”
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