Search Results - "Dockray, Graham J."

The expanding family of -RFamide peptides and their effects on feeding behaviour by Dockray, Graham J.

“…Neuropeptides terminating in -Arg-Phe-NH 2 (-RFamide) were first discovered in molluscan nervous systems, but were soon recognized to occur widely throughout…”
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Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells by Varga, Akos Janos, Nemeth, Istvan Balazs, Kemeny, Lajos, Varga, Janos, Tiszlavicz, Laszlo, Kumar, Dinesh, Dodd, Steven, Simpson, Alec W M, Buknicz, Tunde, Beynon, Rob, Simpson, Deborah, Krenacs, Tibor, Dockray, Graham J, Varro, Andrea

“…Micro-environmental factors, including stromal and immune cells, cytokines, and circulating hormones are well recognized to determine cancer progression…”
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Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells by Kumar, J Dinesh, Holmberg, Chris, Kandola, Sandhir, Steele, Islay, Hegyi, Peter, Tiszlavicz, Laszlo, Jenkins, Rosalind, Beynon, Robert J, Peeney, David, Giger, Olivier T, Alqahtani, Ahlam, Wang, Timothy C, Charvat, Trevor T, Penfold, Mark, Dockray, Graham J, Varro, Andrea

“…Stromal cells such as myofibroblasts influence tumor progression. The mechanisms are unclear but may involve effects on both tumor cells and recruitment of…”
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Gastrointestinal hormones and the dialogue between gut and brain by Dockray, Graham J.

“…The landmark discovery by Bayliss and Starling in 1902 of the first hormone, secretin, emerged from earlier observations that a response (pancreatic secretion)…”
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Cocaine- and Amphetamine-Regulated Transcript: Stimulation of Expression in Rat Vagal Afferent Neurons by Cholecystokinin and Suppression by Ghrelin by de Lartigue, Guillaume, Dimaline, Rod, Varro, Andrea, Dockray, Graham J

“…The neuropeptide transmitter cocaine- and amphetamine-regulated transcript (CART) inhibits food intake and is expressed by both vagal afferent and hypothalamic…”
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EGR1 Is a Target for Cooperative Interactions between Cholecystokinin and Leptin, and Inhibition by Ghrelin, in Vagal Afferent Neurons by de Lartigue, Guillaume, Lur, Gyorgy, Dimaline, Rod, Varro, Andrea, Raybould, Helen, Dockray, Graham J

“…Food intake is regulated by signals from peripheral organs, but the way these are integrated remains uncertain. Cholecystokinin (CCK) from the intestine and…”
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Effects of Proton Pump Inhibitor Therapy, H. pylori Infection and Gastric Preneoplastic Pathology on Fasting Serum Gastrin Concentrations by Veysey-Smith, Reuben, Moore, Andrew R, Murugesan, Senthil V, Tiszlavicz, Laszlo, Dockray, Graham J, Varro, Andrea, Pritchard, D Mark

“…Hypergastrinaemia occasionally indicates the presence of a gastrinoma. However it is much more commonly associated with various benign causes including proton…”
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Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance by Burdyga, Galina, Varro, Andrea, Dimaline, Rod, Thompson, David G, Dockray, Graham J

“…Intact vagal afferent neurons are required for the satiety effects of the intestinal hormone cholecystokinin (CCK) and the orexigenic effects of the gastric…”
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Expression of Cannabinoid CB1 Receptors by Vagal Afferent Neurons Is Inhibited by Cholecystokinin by Burdyga, Galina, Lal, Simon, Varro, Andrea, Dimaline, Rod, Thompson, David G, Dockray, Graham J

“…Both inhibitory (satiety) and stimulatory (orexigenic) factors from the gastrointestinal tract regulate food intake. In the case of the satiety hormone…”
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Cholecystokinin Regulates Expression of Y2 Receptors in Vagal Afferent Neurons Serving the Stomach by Burdyga, Galina, de Lartigue, Guillaume, Raybould, Helen E, Morris, Richard, Dimaline, Rod, Varro, Andrea, Thompson, David G, Dockray, Graham J

“…The intestinal hormones CCK and PYY3-36 inhibit gastric emptying and food intake via vagal afferent neurons. Here we report that CCK regulates the expression…”
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Cocaine- and Amphetamine-Regulated Transcript Mediates the Actions of Cholecystokinin on Rat Vagal Afferent Neurons by De Lartigue, Guillaume, Dimaline, Rod, Varro, Andrea, Raybould, Helen, De La Serre, Claire Barbier, Dockray, Graham J

“…Background & Aims Cholecystokinin (CCK) acts on vagal afferent neurons to inhibit food intake and gastric emptying; it also increases expression of the…”
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Mesenchymal Stem Cells Exhibit Regulated Exocytosis in Response to Chemerin and IGF by Kumar, J Dinesh, Holmberg, Chris, Balabanova, Silvia, Borysova, Lyudmyla, Burdyga, Ted, Beynon, Robert, Dockray, Graham J, Varro, Andrea

“…Mesenchymal stem cells (MSCs) play important roles in tissue repair and cancer progression. Our recent work suggests that some mesenchymal cells, notably…”
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Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency by Jackson, Robert S, Creemers, John W M, Farooqi, I Sadaf, Raffin-Sanson, Marie-Laure, Varro, Andrea, Dockray, Graham J, Holst, Jens J, Brubaker, Patricia L, Corvol, Pierre, Polonsky, Kenneth S, Ostrega, Diane, Becker, Kenneth L, Bertagna, Xavier, Hutton, John C, White, Anne, Dattani, Mehul T, Hussain, Khalid, Middleton, Stephen J, Nicole, Thomasina M, Milla, Peter J, Lindley, Keith J, O'Rahilly, Stephen

“…We have previously described the only reported case of human proprotein convertase 1 (PC1) deficiency, in a female (Subject A) with obesity, hypogonadism,…”
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Defining the Role of Cholecystokinin in the Lipid-Induced Human Brain Activation Matrix by Lassman, Daniel J, McKie, Shane, Gregory, Lloyd J, Lal, Simon, D'Amato, Massimo, Steele, Islay, Varro, Andrea, Dockray, Graham J, Williams, Steven C.R, Thompson, David George

“…Background & Aims In human beings, as in most vertebrates, the release of the intestinal peptide cholecystokinin (CCK) by ingested food plays a major role both…”
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Cholecystokinin by Dockray, Graham J.

“…Cholecystokinin (CCK) controls nutrient delivery to the small intestine by inhibiting food intake and gastric emptying. This review deals with recent work…”
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Enteroendocrine cell signalling via the vagus nerve by Dockray, Graham J

“…Highlights • Vagal afferents to the gut are activated by CCK, leptin, 5HT, GLP-1 and PYY3–36. • The actions of CCK on vagal afferents are potentiated by…”
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Recharacterization data for a geriatric gastrin polycolonal antibody by Dodd, Steven, Varro, Andrea, Pritchard, D. Mark, Dockray, Graham J.

“…Radioimmunoassay data on the recharacterization of a gastrin polycolonal antibody first generated in 1973 is presented. The data include specificity, effect of…”
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Cholecystokinin and gut–brain signalling by Dockray, Graham J.

“…Enteroendocrine cells of the gastrointestinal tract act as a luminal surveillance system responding to either the presence or absence of food in the gut lumen…”
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Insulin-like growth factor binding protein-5 is a target of matrix metalloproteinase-7 : Implications for epithelial-mesenchymal signaling by HEMERS, Elaine, DUVAL, Cedric, MCCAIG, Catherine, HANDLEY, Mark, DOCKRAY, Graham J, VARRO, Andrea

“…Matrix metalloproteinase-7 (MMP-7) is localized to epithelial cells and is up-regulated in many cancers and in inflammation. We now report that MMP-7 targets a…”
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The versatility of the vagus by Dockray, Graham J

“…Abstract The gut is one of several organs contributing to the peripheral signalling network that controls food intake. Afferent neurons of the vagus nerve…”
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