Search Results - "Dockerill, Millicent"
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A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules
Published in Nature chemistry (01-02-2022)“…DNA-encoded library technologies enable the screening of synthetic molecules but have thus far not tapped into the power of Darwinian selection with iterative…”
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Translation of Deoxyribonucleic Acid into Synthetic Alpha Helical Peptides for Darwinian Evolution
Published in JACS Au (28-10-2024)“…DNA-encoded libraries connect the phenotypes of synthetic molecules to a DNA barcode; however, most libraries do not tap into the potential of Darwinian…”
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DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution
Published in Angewandte Chemie International Edition (20-02-2023)“…DNA‐encoded library (DEL) technologies are transforming the drug discovery process, enabling the identification of ligands at unprecedented speed and scale…”
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DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution
Published in Angewandte Chemie (20-02-2023)“…DNA‐encoded library (DEL) technologies are transforming the drug discovery process, enabling the identification of ligands at unprecedented speed and scale…”
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Journal Article -
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Development of supramolecular anticoagulants with on-demand reversibility
Published in Nature biotechnology (30-04-2024)“…Drugs are administered at a dosing schedule set by their therapeutic index, and termination of action is achieved by clearance and metabolism of the drug. In…”
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Journal Article