Search Results - "Doche, E."

Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19 by Ha, Dat P, Shin, Woo-Jin, Liu, Ze, Doche, Michael E, Lau, Roy, Leli, Nektaria Maria, Conn, Crystal S, Russo, Mariangela, Lorenzato, Annalisa, Koumenis, Constantinos, Yu, Min, Mumenthaler, Shannon M, Lee, Amy S

“…Despite recent therapeutic advances, combating cancer resistance remains a formidable challenge. The 78-kilodalton glucose-regulated protein (GRP78), a key…”
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Angioedema associated with thrombolysis for ischemic stroke: analysis of a case‐control study by Vigneron, C., Lécluse, A., Ronzière, T., Bouillet, L., Boccon‐Gibod, I., Gayet, S., Doche, E., Smadja, D., Di Legge, S., Dumont, F., Gaudron, M., Ion, I., Marcel, S., Sévin, M., Vlaicu, M. B., Launay, D., Arnaud, I., Girard‐Madoux, P., Héroum, C., Lefèvre, S., Marc, G., Obadia, M., Sablot, D., Sibon, I., Suissa, L., Gobert, D., Detante, O., Alamowitch, S., Fain, O., Javaud, N.

“…Background Bradykinin‐mediated angioedema (AE) is a complication associated with thrombolysis for acute ischemic stroke. Risk factors are unknown and…”
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Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate by Ma, Zhaoxuan, Shiao, Stephen L, Yoshida, Emi J, Swartwood, Steven, Huang, Fangjin, Doche, Michael E, Chung, Alice P, Knudsen, Beatrice S, Gertych, Arkadiusz

“…Immune cell infiltrates (ICI) of tumors are scored by pathologists around tumor glands. To obtain a better understanding of the immune infiltrate, individual…”
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T.P.15 by Doche, E, Salort-Campana, E, Le Troter, A, Attarian, S, Pouget, J, Bendahan, D

“…Considering the clinical heterogeneity of patients with a late onset form of Pompe disease, we clearly need reliable quantitative surrogate markers allowing to…”
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A challenging case study resolved by using the Dynamic Laser Stimulation technique by Deyine, A., Doche, E., Battistella, F., Banc, C.

“…The case study device shows an abnormal electrical behavior after a few years of operation whereas new devices are normal. This abnormal behavior is proved to…”
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High performance electronics in long lifetime, continuous operation, industrial products: The art of balancing conflicting interests by Banc, C., Guinet, J., Doche, E.

“…As more and more electronics is being integrated in industrial systems that used to be purely electro-technical (breakers, industrial relays, etc.), the…”
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Human SH2B1 mutations are associated with maladaptive behaviors and obesity by Doche, Michael E, Bochukova, Elena G, Su, Hsiao-Wen, Pearce, Laura R, Keogh, Julia M, Henning, Elana, Cline, Joel M, Saeed, Sadia, Dale, Anne, Cheetham, Tim, Barroso, Inês, Argetsinger, Lawrence S, O'Rahilly, Stephen, Rui, Liangyou, Carter-Su, Christin, Farooqi, I Sadaf

“…Src homology 2 B adapter protein 1 (SH2B1) modulates signaling by a variety of ligands that bind to receptor tyrosine kinases or JAK-associated cytokine…”
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Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis by Ehrhardt, Nicole, Doche, Michael E, Chen, Shuang, Mao, Hui Z, Walsh, Meghan T, Bedoya, Candy, Guindi, Maha, Xiong, Weidong, Ignatius Irudayam, Joseph, Iqbal, Jahangir, Fuchs, Sebastien, French, Samuel W, Mahmood Hussain, M, Arditi, Moshe, Arumugaswami, Vaithilingaraja, Péterfy, Miklós

“…The human transmembrane 6 superfamily member 2 (TM6SF2) gene has been implicated in plasma lipoprotein metabolism, alcoholic and non-alcoholic fatty liver…”
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Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance by Garvey, Colleen M., Lau, Roy, Sanchez, Alyssa, Sun, Ren X., Fong, Emma J., Doche, Michael E., Chen, Oscar, Jusuf, Anthony, Lenz, Heinz-Josef, Larson, Brent, Mumenthaler, Shannon M.

“…Targeted agents have improved the efficacy of chemotherapy for cancer patients, however, there remains a lack of understanding of how these therapies affect…”
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The nucleolar δ isoform of adapter protein SH2B1 enhances morphological complexity and function of cultured neurons by Cote, Jessica L, Vander, Paul B, Ellis, Michael, Cline, Joel M, Svezhova, Nadezhda, Doche, Michael E, Maures, Travis J, Choudhury, Tahrim A, Kong, Seongbae, Klaft, Olivia G J, Joe, Ray M, Argetsinger, Lawrence S, Carter-Su, Christin

“…The adapter protein SH2B1 is recruited to neurotrophin receptors, including TrkB (also known as NTRK2), the receptor for brain-derived neurotrophic factor…”
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Phosphorylation of the Unique C-Terminal Tail of the Alpha Isoform of the Scaffold Protein SH2B1 Controls the Ability of SH2B1α To Enhance Nerve Growth Factor Function by Joe, Ray M., Flores, Anabel, Doche, Michael E., Cline, Joel M., Clutter, Erik S., Vander, Paul B., Riedel, Heimo, Argetsinger, Lawrence S., Carter-Su, Christin

“…The scaffold protein SH2B1, a major regulator of body weight, is recruited to the receptors of multiple cytokines and growth factors, including nerve growth…”
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Functional Characterization of Obesity-Associated Variants Involving the α and β Isoforms of Human SH2B1 by Pearce, Laura R, Joe, Ray, Doche, Michael E, Su, Hsiao-Wen, Keogh, Julia M, Henning, Elana, Argetsinger, Lawrence S, Bochukova, Elena G, Cline, Joel M, Garg, Sumedha, Saeed, Sadia, Shoelson, Steven, O'Rahilly, Stephen, Barroso, Inês, Rui, Liangyou, Farooqi, I. Sadaf, Carter-Su, Christin

“…We have previously reported rare variants in sarcoma (Src) homology 2 (SH2) B adaptor protein 1 (SH2B1) in individuals with obesity, insulin resistance, and…”
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Study of the ESD defects impact on ICs reliability by ESSELY, F, BESTORY, C, GUITARD, N, BAFLEUR, M, WISLEZ, A, DOCHE, E, PERDU, P, TOUBOUL, A, LEWIS, D

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Une migraine prolongée by FAIVRE, A, LA FOLIE, T, DAGAIN, A, DOCHE, E, CURET, C, WYBRECHT, D, BOUNOLLEAU, P, ALLA, P

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T.P.15: Enzymotherapy in late onset Pompe disease patients: a 4-year longitudinal study using quantitative MRI by Doche, E., Salort-Campana, E., Le Troter, A., Attarian, S., Pouget, J., Bendahan, D.

“…Considering the clinical heterogeneity of patients with a late onset form of Pompe disease, we clearly need reliable quantitative surrogate markers allowing to…”
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Le régime cétogène modifie le métabolisme glucidique cérébral régional : une étude clinique semi-quantitative en TEP au [18F]FDG by Horowitz, T., Doche, E., Philip, M., Cammilleri, S., Suissa, L., Guedj, E.

“…Le régime cétogène (RC) est utilisé en routine pour éviter une fixation physiologique intense myocardique du [18F]FDG en imagerie TEP. De plus en plus d’études…”
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Récupération clinico-radiologique d’un syndrome d’embolie graisseuse cérébrale chez un patient drépanocytaire by Richaud, L., Bertolino, J., Gutierrez, B., Meunier, B., Ecosse, Q., Doddoli, S., Jean, E., Doche, E., Brunel, H., Schleinitz, N., Bernit, E.

“…La drépanocytose est une hémoglobinopathie génétique, responsable d’une anémie hémolytique chronique et de phénomènes vaso-occlusifs pouvant atteindre tous les…”
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L’hypoperfusion du thalamus est corrélé au handicap dans la SEP de forme rémittente by Doche, E., Maarouf, A., Rico, A., Zaaraoui, W., Ranjeva, J.-P., Audoin, B., Pelletier, J.

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An extended migraine by Faivre, A, La Folie, T, Dagain, A, Doche, E, Curet, C, Wybrecht, D, Bounolleau, P, Alla, P

“…Migrainous infarction is a rare ischemic stroke developing during an attack of migraine, which is more prevalent in young woman and preferentially affects the…”
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Abstract 2694: Receptor-interacting protein kinase 2 promotes prostate cancer progression by activating the MAX:MYC pathway by Yan, Yiwu, Zhou, Bo, Yuan, Xiaopu, Doche, Michael E., Ma, Zhaoxuan, Morrissey, Colm, Gertych, Arkadiusz, You, Sungyong, Knudsen, Beatrice, Freeman, Michael R., Yang, Wei

“…Abstract Background: Prostate Cancer (PCa) is the most common non-skin cancer among American man. Currently, major challenges in the clinical management of PCa…”
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