Search Results - "Docena, Guillermo H"
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A novel approach to ameliorate experimental milk allergy based on the oral administration of a short soy cross-reactive peptide
Published in Food chemistry (01-06-2021)“…•A soy peptide presents cross-reactive immunodominant T epitopes with bovine caseins.•A soy peptide presents cross-reactive immunodominant B epitopes with…”
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Characterization of protein cargo of Echinococcus granulosus extracellular vesicles in drug response and its influence on immune response
Published in Parasites & vectors (29-07-2023)“…The Echinococcus granulosus sensu lato species complex causes cystic echinococcosis, a zoonotic disease of medical importance. Parasite-derived small…”
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Probiotic Lactobacilli Isolated from Kefir Promote Down-Regulation of Inflammatory Lamina Propria T Cells from Patients with Active IBD
Published in Frontiers in pharmacology (15-04-2021)“…Ulcerative colitis and Crohn's disease, the two main forms of inflammatory bowel disease (IBD), are immunologically mediated disorders. Several therapies are…”
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The Role of Cytokines in the Fibrotic Responses in Crohn's Disease
Published in Frontiers in medicine (07-08-2017)“…Crohn's disease is an idiopathic disorder of the gut thought to be caused by a combination of environmental and genetic factors in susceptible individuals. It…”
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Mucosal Immunoregulatory Properties of Tsukamurella inchonensis to Reverse Experimental Food Allergy
Published in Frontiers in immunology (30-04-2021)“…The intestinal mucosa is lined by epithelial cells, which are key cells to sustain gut homeostasis. Food allergy is an immune-mediated adverse reaction to…”
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A galectin-specific signature in the gut delineates Crohn's disease and ulcerative colitis from other human inflammatory intestinal disorders
Published in BioFactors (Oxford) (01-01-2016)“…Inflammatory bowel diseases (IBD) are chronic and relapsing inflammatory conditions of the gastrointestinal tract including Crohn's disease (CD) and ulcerative…”
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Use of a Collagen Membrane to Enhance the Survival of Primary Intestinal Epithelial Cells
Published in Journal of cellular physiology (01-09-2017)“…Intestinal epithelial cell culture is important for biological, functional, and immunological studies. Since enterocytes have a short in vivo life span due to…”
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Targeting a cross-reactive Gly m 5 soy peptide as responsible for hypersensitivity reactions in a milk allergy mouse model
Published in PloS one (09-01-2014)“…Cross-reactivity between soybean allergens and bovine caseins has been previously reported. In this study we aimed to map epitopes of the major soybean…”
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Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies
Published in Journal of inflammation research (01-01-2020)“…Proteases play an essential role in the pathophysiology of inflammatory bowel disease (IBD), contributing to the intestinal mucosal lesions through the…”
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Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins
Published in PloS one (05-07-2013)“…The discovery of novel mucosal adjuvants will help to develop new formulations to control infectious and allergic diseases. In this work we demonstrate that…”
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The role of transforming growth factor (TGF)-β in modulating the immune response and fibrogenesis in the gut
Published in Cytokine & growth factor reviews (01-02-2014)“…Abstract Transforming growth factor (TGF)-β, a pleiotropic cytokine released by both immune and non-immune cells in the gut, exerts an important tolerogenic…”
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Peptides of amaranth were targeted as containing sequences with potential anti-inflammatory properties
Published in Journal of functional foods (01-03-2016)“…•Hydrolysis of amaranth proteins releases peptides endowed with anti-inflammatory activity.•SSDEIKE peptide shows inhibitory properties on activated Caco-2…”
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Volcanic ash-driven worsening of mucosal inflammation in an experimental colitis model
Published in Environmental pollution (1987) (01-01-2022)“…Particulate matter exposure and related chemical changes in drinking water have been associated with health problems and inflammatory disorders. This study…”
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Carbonylation induced by antibiotic and pesticide residues on casein increases its IgE binding and allergenicity
Published in Free radical research (02-01-2022)“…This work aimed to evaluate the effect of carbonylation induced by tetracyclines, β-lactams, fluoroquinolones, and pyrethroids in caseins of bovine origin on…”
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Spatiotemporal regulation of galectin-1-induced T-cell death in lamina propria from Crohn’s disease and ulcerative colitis patients
Published in Apoptosis (London) (01-06-2021)“…Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is characterized by chronic, relapsing intestinal inflammation…”
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Inflammation Controls Sensitivity of Human and Mouse Intestinal Epithelial Cells to Galectin-1
Published in Journal of cellular physiology (01-07-2016)“…Galectins play key roles in the inflammatory cascade. In this study, we aimed to analyze the effect of galectin‐1 (Gal‐1) in the function of intestinal…”
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The anti-inflammatory SSEDIKE peptide from Amaranth seeds modulates IgE-mediated food allergy
Published in Journal of functional foods (01-08-2016)“…•A peptide derived from Amaranthus hypochondriacus alleviated experimental food allergy.•The oral administration of the peptide suppressed IgE secretion and…”
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Down-regulation of NF-κB signaling by Gordonia bronchialis prevents the activation of gut epithelial cells
Published in Innate immunity (London, England) (01-08-2014)“…The immunomodulatory power of heat-killed Gordonia bronchialis was studied on gut epithelial cells activated with pro-inflammatory stimuli (flagellin, TNF-α or…”
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Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits
Published in Science advances (01-06-2021)“…Glycosylation-dependent programs control intestinal inflammation. Diverse immunoregulatory circuits operate to preserve intestinal homeostasis and prevent…”
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Mo1713 The Role of the Galectin-1 in the Pathogenesis of IBD
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2014)Get full text
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