Search Results - "Dobson, Adam"

Toward Stimuli‐Responsive Dynamic Thermosets through Continuous Development and Improvements in Covalent Adaptable Networks (CANs) by Podgórski, Maciej, Fairbanks, Benjamin D., Kirkpatrick, Bruce E., McBride, Matthew, Martinez, Alina, Dobson, Adam, Bongiardina, Nicholas J., Bowman, Christopher N.

“…Covalent adaptable networks (CANs), unlike typical thermosets or other covalently crosslinked networks, possess a unique, often dormant ability to activate one…”
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Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut by Dutta, Devanjali, Dobson, Adam J., Houtz, Philip L., Gläßer, Christine, Revah, Jonathan, Korzelius, Jerome, Patel, Parthive H., Edgar, Bruce A., Buchon, Nicolas

“…Deciphering contributions of specific cell types to organ function is experimentally challenging. The Drosophila midgut is a dynamic organ with five…”
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A Comprehensive, Multidimensional First‐Principles Model for Free‐Radical Photopolymerizations in Bulk and Thin Films by Dobson, Adam L., Bowman, Christopher N.

“…Decades of advances in understanding and simulating the polymerization kinetics and structural evolution that arises in free‐radical photopolymerizations of…”
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Acetobacter pomorum in the Drosophila gut microbiota buffers against host metabolic impacts of dietary preservative formula and batch variation in dietary yeast by Sannino, David R, Dobson, Adam J

“…Gut microbiota are fundamentally important for healthy function in animal hosts. is a powerful system for understanding host-microbiota interactions, with…”
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Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction by Regan, Jennifer C, Khericha, Mobina, Dobson, Adam J, Bolukbasi, Ekin, Rattanavirotkul, Nattaphong, Partridge, Linda

“…Women live on average longer than men but have greater levels of late-life morbidity. We have uncovered a substantial sex difference in the pathology of the…”
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Host Genetic Control of the Microbiota Mediates the Drosophila Nutritional Phenotype by Chaston, John M, Dobson, Adam J, Newell, Peter D, Douglas, Angela E

“…A wealth of studies has demonstrated that resident microorganisms (microbiota) influence the pattern of nutrient allocation to animal protein and energy…”
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Comparing selection on S. aureus between antimicrobial peptides and common antibiotics by Dobson, Adam J, Purves, Joanne, Kamysz, Wojciech, Rolff, Jens

“…With a diminishing number of effective antibiotics, there has been interest in developing antimicrobial peptides (AMPs) as drugs. However, any new drug faces…”
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Gut microbiota dictates the metabolic response of Drosophila to diet by Wong, Adam C-N, Dobson, Adam J, Douglas, Angela E

“…Animal nutrition is profoundly influenced by the gut microbiota, but knowledge of the scope and core mechanisms of the underlying animal-microbiota…”
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Mitonuclear interactions shape both direct and parental effects of diet on fitness and involve a SNP in mitoribosomal 16s rRNA by Dobson, Adam J, Voigt, Susanne, Kumpitsch, Luisa, Langer, Lucas, Voigt, Emmely, Ibrahim, Rita, Dowling, Damian K, Reinhardt, Klaus

“…Nutrition is a primary determinant of health, but responses to nutrition vary with genotype. Epistasis between mitochondrial and nuclear genomes may cause some…”
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The Drosophila melanogaster Gut Microbiota Provisions Thiamine to Its Host by Sannino, David R, Dobson, Adam J, Edwards, Katie, Angert, Esther R, Buchon, Nicolas

“…The microbiota of has a substantial impact on host physiology and nutrition. Some effects may involve vitamin provisioning, but the relationships between…”
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Rapamycin's lifespan effect is modulated by mito-nuclear epistasis in Drosophila by Ibrahim, Rita, Bahilo Martinez, Maria, Dobson, Adam J

“…The macrolide drug rapamycin is a benchmark anti-ageing drug, which robustly extends lifespan of diverse organisms. For any health intervention, it is…”
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Controlled Degradation of Cast and 3‑D Printed Photocurable Thioester Networks via Thiol–Thioester Exchange by Hernandez, Juan J, Dobson, Adam L, Carberry, Benjamin J, Kuenstler, Alexa S, Shah, Parag K, Anseth, Kristi S, White, Timothy J, Bowman, Christopher N

“…This work examined and quantitatively predicted the degradation of thioester-containing networks facilitated by base-catalyzed thiol–thioester exchange. A…”
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Longevity is determined by ETS transcription factors in multiple tissues and diverse species by Dobson, Adam J, Boulton-McDonald, Richard, Houchou, Lara, Svermova, Tatiana, Ren, Ziyu, Subrini, Jeremie, Vazquez-Prada, Mireya, Hoti, Mimoza, Rodriguez-Lopez, Maria, Ibrahim, Rita, Gregoriou, Afroditi, Gkantiragas, Alexis, Bähler, Jürg, Ezcurra, Marina, Alic, Nazif

“…Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific…”
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The importance of reaction norms in dietary restriction and ageing research by Simons, Mirre J.P., Dobson, Adam J.

“…Ageing research has progressed rapidly through our ability to modulate the ageing process. Pharmacological and dietary treatments can increase lifespan and…”
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RNA polymerase III limits longevity downstream of TORC1 by Filer, Danny, Thompson, Maximillian A., Takhaveev, Vakil, Dobson, Adam J., Kotronaki, Ilektra, Green, James W. M., Heinemann, Matthias, Tullet, Jennifer M. A., Alic, Nazif

“…RNA polymerase III is a key evolutionarily conserved regulator of longevity that may have potential as a therapeutic target for age-related conditions. Pol III…”
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Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size by Bonfini, Alessandro, Dobson, Adam J, Duneau, David, Revah, Jonathan, Liu, Xi, Houtz, Philip, Buchon, Nicolas

“…The gut is the primary interface between an animal and food, but how it adapts to qualitative dietary variation is poorly defined. We find that the midgut…”
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The Drosophila transcriptional network is structured by microbiota by Dobson, Adam J, Chaston, John M, Douglas, Angela E

“…Resident microorganisms (microbiota) have far-reaching effects on the biology of their animal hosts, with major consequences for the host's health and fitness…”
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Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster by Dobson, Adam J., Chaston, John M., Newell, Peter D., Donahue, Leanne, Hermann, Sara L., Sannino, David R., Westmiller, Stephanie, Wong, Adam C.-N., Clark, Andrew G., Lazzaro, Brian P., Douglas, Angela E.

“…Animals bear communities of gut microorganisms with substantial effects on animal nutrition, but the host genetic basis of these effects is unknown. Here we…”
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Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets by Dobson, Adam J., Ezcurra, Marina, Flanagan, Charlotte E., Summerfield, Adam C., Piper, Matthew D.W., Gems, David, Alic, Nazif

“…Consumption of unhealthy diets is exacerbating the burden of age-related ill health in aging populations. Such diets can program mammalian physiology to cause…”
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Combined Dynamic Network and Filler Interface Approach for Improved Adhesion and Toughness in Pressure-Sensitive Adhesives by Dobson, Adam L, Bongiardina, Nicholas J, Bowman, Christopher N

“…Of importance for adhesive materials, particularly pressure-sensitive adhesive (PSA) systems, is the ability to increase bulk toughness without reduction of…”
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