Search Results - "Dobrotova Miroslava"
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Comparison of clinical phenotype with genetic and laboratory results in 31 patients with congenital dysfibrinogenemia in northern Slovakia
Published in International journal of hematology (01-06-2020)“…Congenital dysfibrinogenemia (CD) is a rare disorder of hemostasis. The majority of cases are caused by heterozygous missense mutations in one of the three…”
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Apixaban - Metabolism, Pharmacologic Properties and Drug Interactions
Published in Current drug metabolism (01-01-2017)“…Apixaban is an oral, potent, highly selective, reversible and direct inhibitor of activated coagulation factor X, that is the end point of the intrinsic and…”
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How can Secondary Thromboprophylaxis in High-Risk Pregnant Patients be Improved?
Published in Clinical and applied thrombosis/hemostasis (01-02-2022)“…Low-molecular-weight heparin (LMWH) is suggested for thromboprophylaxis in pregnant women with previous venous thromboembolism (VTE). Anyway, there is only…”
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Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management
Published in Diagnostics (Basel) (19-11-2021)“…Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative…”
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A Novel Nonsense Mutation in FGB (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype
Published in Biomedicines (13-12-2020)“…Congenital hypofibrinogenemia is a rare bleeding disorder characterized by a proportional decrease of functional and antigenic fibrinogen levels…”
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At-risk Pregnant Woman with Sticky Platelet Syndrome, Previous Recurrent Preeclampsia, and Current Proteinuria - A Rare Experience
Published in Revista de investigacion clinica (01-01-2023)Get full text
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Association of Genetic Variability in Selected Genes with Platelet Hyperaggregability and Arterial Thrombosis
Published in Acta Medica Martiniana (01-04-2022)“…Introduction: Inherited platelet hyperaggregability, so called “Sticky platelet syndrome” (SPS), is a prothrombotic platelet disorder. The syndrome contributes…”
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Monitoring of dabigatran therapy using Hemoclot® Thrombin Inhibitor assay in patients with atrial fibrillation
Published in Journal of thrombosis and thrombolysis (01-01-2015)“…Dabigatran, a new direct thrombin inhibitor, achieves strong anticoagulation that is more predictable than warfarin. Nevertheless, a patient on dabigatran…”
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Multimer Analysis of Von Willebrand Factor in Von Willebrand Disease with a Hydrasys Semi-Automatic Analyzer-Single-Center Experience
Published in Diagnostics (Basel) (20-11-2021)“…von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder. This disorder develops as a result of defects and/or deficiency of the…”
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DNA Polymorphisms in Pregnant Women with Sticky Platelet Syndrome
Published in Journal of clinical medicine (03-11-2022)“…Sticky platelet syndrome (SPS) is a thrombophilia caused by the increased aggregability of platelets in response to the addition of low concentrations of…”
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How Can Rotational Thromboelastometry as a Point-of-Care Method Be Useful for the Management of Secondary Thromboprophylaxis in High-Risk Pregnant Patients?
Published in Diagnostics (Basel) (03-05-2021)“…Thromboprophylaxis with low-molecular-weight heparin (LMWH) for patients with a history of venous thromboembolism (VTE) is suggested. Rotational…”
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Long-term secondary prophylaxis with recombinant activated factor VII (rFVIIa) in haemophilia A with inhibitors: a case report
Published in Thrombosis and haemostasis (01-04-2010)Get more information
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in vitro testing of chemoresistance in leukaemic patients
Published in Biológia (01-02-2009)“…The fact that leukaemic cells are primarily or secondarily resistant to cytostatics is a serious phenomenon, which leads to the failure of chemotherapy of…”
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Variability of GP6 gene in patients with sticky platelet syndrome and deep venous thrombosis and/or pulmonary embolism
Published in Blood coagulation & fibrinolysis (01-09-2012)“…The GP6 gene encodes the GPVI, a crucial platelet membrane glycoprotein, for adequate platelet activation, adhesion and aggregation. The objectives of the…”
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Yes or no for secondary prophylaxis in afibrinogenemia?
Published in Blood coagulation & fibrinolysis (01-12-2015)Get full text
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Heterogeneity of Genotype-Phenotype in Congenital Hypofibrinogenemia-A Review of Case Reports Associated with Bleeding and Thrombosis
Published in Journal of clinical medicine (18-02-2022)“…Congenital fibrinogen disorders are diseases associated with a bleeding tendency; however, there are also reports of thrombotic events. Fibrinogen plays a role…”
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Congenital afibrinogenemia: from etiopathogenesis to challenging clinical management
Published in Expert review of hematology (02-07-2016)“…Congenital afibrinogenemia belongs to the group of autosomal recessive bleeding disorders and represents the absolute deficiency of fibrinogen detected by an…”
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