Search Results - "Dobra, Rebecca"

Going the Extra Mile: Why Clinical Research in Cystic Fibrosis Must Include Children by Dobra, Rebecca, Bentley, Siân, Edmondson, Claire, Ovens, Maxine, Saunders, Clare, Short, Christopher, Wilson, Gemma, Davies, Jane C, Bush, Andrew

“…This is an exciting time for research and novel drug development in cystic fibrosis. However, rarely has the adage, “Children are not just little adults” been…”
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Levelling the playing field through the London Network of the UK clinical trials accelerator platform by Matthews, Jessie, Dobra, Rebecca, Wilson, Gemma, Allen, Lucy, Bossley, Cara, Brendell, Rebecca, Brugha, Rossa, Brown, Danielle, Brown, Sarah, Cadiente, Shenna, Cameron, Loren, Davies, Gwyneth, Dawson, Charlotte, Elborn, Stuart, Hughes, Dominic, Longmate, Jess, Macedo, Patricia, Pappas, Leonidas, Pao, Caroline, Round, Chris, Ruiz, Gary, Saunders, Clare, Shafi, Nadia, Simmonds, Nicholas, Waller, Michael, Watson, Danie, Davies, Jane C.

“…Cystic fibrosis (CF) is a multisystem, genetic disease with a significantly reduced life expectancy. Despite substantial progress in therapies in the last…”
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Discrete choice experiment (DCE) to quantify the influence of trial features on the decision to participate in cystic fibrosis (CF) clinical trials by Dobra, Rebecca Anne, Boeri, Marco, Elborn, Stuart, Kee, Frank, Madge, Susan, Davies, Jane C

“…IntroductionEngaging people with cystic fibrosis (CF) in clinical trials is critical to improving outcomes for this fatal disease. Following extensive…”
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How to use peak expiratory flow rate by Dobra, Rebecca, Equi, Amanda

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A discrete choice experiment to quantify the influence of trial features on the decision to participate in cystic fibrosis trials by Dobra, Rebecca, Davies, Jane, Elborn, Stuart, Kee, Frank, Madge, Susan, Boeri, Marco

“…•It is vital to incorporate patient views into trial design.•We used complex experimental design to find out what pwCF value most when deciding whether to take…”
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Chronicity Counts: The Impact of Pseudomonas aeruginosa , Staphylococcus aureus , and Coinfection in Cystic Fibrosis by Mossop, Micaela, Ish-Horowicz, Jonathan, Hughes, Dominic, Dobra, Rebecca, Cunanan, Alessandra G, Rosenthal, Mark, Carr, Siobhán B, Ramadan, Newara, Nolan, Laura M, Davies, Jane C

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Entering the era of highly effective modulator therapies by Dave, Kavita, Dobra, Rebecca, Scott, Sandra, Saunders, Clare, Matthews, Jess, Simmonds, Nicholas J., Davies, Jane C.

“…Since the discovery of the gene responsible for cystic fibrosis (CF) in 1989, hopes have been pinned on a future with novel therapies tackling the basis of the…”
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How representative are clinical trial cohorts of the general CF population? Implications for trial planning by Dobra, Rebecca, Pinnell, Sophie, Jones, Andy, Madge, Susan, Simmonds, Nicholas J, Davies, Jane C

“…•Restrictive eligibility criteria lead to non-representative cohorts of patients participating in research and reduce the numbers of patients available to take…”
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Disease-modifying drug therapy in cystic fibrosis by Harman, Katharine, Dobra, Rebecca, Davies, Jane C

“…Summary Whilst substantial progress has been made in the treatment of cystic fibrosis, the disease still carries a significant burden in terms of symptoms,…”
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Who and why; sharing our experiences of developing a standard operating procedure (SOP) to allocate screening slots for highly competitive cystic fibrosis trials by Dobra, Rebecca, Scott, Sandra, Davies, Jane C, Simmonds, Nicholas J

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Exploring the complexity of cystic fibrosis (CF) and psychosocial wellbeing in the 2020s: Current and future challenges by Dobra, Rebecca, Carroll, Sarah, Davies, Jane C., Dowdall, Fiona, Duff, Alistair, Elderton, Anna, Georgiopoulos, Anna M., Massey-Chase, Rachel, McNally, Paul, Puckey, Michèle, Madge, Susan

“…The reader will come to appreciate:•Despite transformative change in the management of CF in the last decade, the past few years have also brought important…”
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“Fortunate are those who take the first steps”? The psychosocial impact of novel drug development by Dobra, Rebecca, Madge, Susan, Martin, Isaac, Weldon, Paul, Simmonds, Nicholas, Davies, Jane C.

“…Novel drug development offers people with cystic fibrosis exciting opportunities but is not without challenges. Currently, there is an understandable emphasis…”
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A systematic review to identify and collate factors influencing patient journeys through clinical trials by Dobra, Rebecca, Wilson, Gemma, Matthews, Jessie, Boeri, Marco, Elborn, Stuart, Kee, Frank, Davies, Jane C, Madge, Susan

“…Summary Patient-centred trial design and delivery; improves recruitment and retention; increases participant satisfaction; encourages participation by a more…”
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