Search Results - "Dobo, S."

P826: FACTOR D INHIBITION WITH ORAL BCX9930 LEADS TO SUSTAINED CONTROL OF HEMOLYSIS AND SYMPTOMS OVER 48 WEEKS IN SUBJECTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA INADEQUATELY CONTROLLED ON C5 INHIBITORS by Kulasekararaj, A., Füreder, W., McDonald, A., Malherbe, J. L. R., Gandhi, S., Collins, D., Cornpropst, M., Dobo, S., Farmer, M. K., Kargl, D., Sheridan, W., Griffin, M., Risitano, A.

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PHARMACOKINETICS AND PHARMACODYNAMICS OF BCX7353, AN ORAL PLASMA KALLIKREIN INHIBITOR, IN HEALTHY JAPANESE SUBJECTS by Cornpropst, M., Dobo, S., Collis, P., Collier, J., Sheridan, W.

“…BCX7353 is an oral kallikrein inhibitor being studied for prevention and treatment of hereditary angioedema (HAE) attacks in Western patients. HAE afflicts all…”
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Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema by Aygören-Pürsün, Emel, Bygum, Anette, Grivcheva-Panovska, Vesna, Magerl, Markus, Graff, Jochen, Steiner, Urs C, Fain, Olivier, Huissoon, Aarnoud, Kinaciyan, Tamar, Farkas, Henriette, Lleonart, Ramon, Longhurst, Hilary J, Rae, William, Triggiani, Massimo, Aberer, Werner, Cancian, Mauro, Zanichelli, Andrea, Smith, William B, Baeza, Maria L, Du-Thanh, Aurelie, Gompels, Mark, Gonzalez-Quevedo, Teresa, Greve, Jens, Guilarte, Mar, Katelaris, Constance, Dobo, Sylvia, Cornpropst, Melanie, Clemons, Desiree, Fang, Lei, Collis, Phil, Sheridan, William, Maurer, Marcus, Cicardi, Marco

“…The clinical consequences of defects in C1 inhibitor function can be serious. A series of advances have improved the outlook for patients with hereditary…”
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Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS‐2 study by Riedl, M. A., Aygören‐Pürsün, E., Baker, J., Farkas, H., Anderson, J., Bernstein, J. A., Bouillet, L., Busse, P., Manning, M., Magerl, M., Gompels, M., Huissoon, A. P., Longhurst, H., Lumry, W., Ritchie, B., Shapiro, R., Soteres, D., Banerji, A., Cancian, M., Johnston, D. T., Craig, T. J., Launay, D., Li, H. H., Liebhaber, M., Nickel, T., Offenberger, J., Rae, W., Schrijvers, R., Triggiani, M., Wedner, H. J., Dobo, S., Cornpropst, M., Clemons, D., Fang, L., Collis, P., Sheridan, W. P., Maurer, M.

“…Background Effective inhibition of plasma kallikrein may have significant benefits for patients with hereditary angioedema due to deficiency of C1 inhibitor…”
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P154 SAFETY AND TOLERABILITY OF ONCE-DAILY ORAL KALLIKREIN INHIBITOR BCX7353 IN PHASE 3 APEX-2 HAE STUDY by Riedl, M., Lumry, W., Banerji, A., Aygoren-Pursun, E., Bernstein, J., Maurer, M., Cicardi, M., Christiansen, S., Zuraw, B., Dobo, S., Cornpropst, M., Iocca, H., Nagy, E., Murray, S., Collis, P., Sheridan, W., Johnston, D.

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P150 ORAL PROPHYLAXIS WITH BCX7353 REDUCES HAE ATTACK RATES AND IS WELL-TOLERATED: APEX-2 STUDY RESULTS by Zuraw, B., Lumry, W., Banerji, A., Aygoren-Pursun, E., Bernstein, J., Johnston, D., Christiansen, S., Riedl, M., Cicardi, M., Maurer, M., Cornpropst, M., Dobo, S., Iocca, H., Nagy, E., Murray, S., Collis, P., Sheridan, W.

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PHARMACOKINETICS AND PHARMACODYNAMICS OF BCX7353, AN ORAL PLASMA KALLIKREIN INHIBITOR, IN HEALTHY JAPANESE SUBJECTS by Cornpropst, M., Dobo, S., Collis, P., Collier, J., Sheridan, W.

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P507 BCX7353: An effective and safe oral prophylaxis against attacks of hereditary angioedema. apex-1 final results by Aygören-Pürsün, E., Bygum, A., Panovska, V. Grivcheva, Steiner, U., Huissoon, A., Kinaciyan, T., Fain, O., Longhurst, H., Farkas, H., Fang, L., Cornpropst, M., Clemons, D., Dobo, S., Maurer, M., Cicardi, M.

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Protocole d’utilisation thérapeutique (PUT) et de recueil d’informations du Berotralstat dans le cadre de l’autorisation temporaire d’utilisation de cohorte (ATUc) de l’Agence Nationale de Sécurité du Médicament (ANSM) by Bouillet, L., Boccon-Gibod, I., Gobert, D., Fain, O., De Sauvebeuf, C., Eniko, N., Dobo, S., Collis, P., Sisic, Z., Crave, J.C., De Narbonne, L., Launay, D.

“…Une ATUc est une procédure spécifique permettant une utilisation exceptionnelle de spécialités pharmaceutiques sans autorisation de mise sur le marché. Une…”
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Compartment Syndrome in the Critically Injured following Massive Resuscitation: Case Reports by Block, Ernest F. J., Dobo, Sylvia, Kirton, Orlando C.

“…Compartment syndrome of the extremities is usually associated with locally mediated events such as ischemia or injury. Three cases are presented of patients…”
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The drug treatment of hypertension by WOLF, R L, MENDLOWITZ, M, WEIGL, A, COHEN, E S, KORNFELD, P, DOBO, S, GITLOW, S E, NAFTCHI, N E

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Has the 2005 measles mortality reduction goal been achieved? A natural history modelling study by Wolfson, Lara J, Dr, Strebel, Peter M, MBChB, Gacic-Dobo, Marta, BS, Hoekstra, Edward J, MD, McFarland, Jeffrey W, MD, Hersh, Bradley S, MD

“…Summary Background In 2002, the UN General Assembly Special Session on Children adopted a goal to reduce deaths owing to measles by half by the end of 2005,…”
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Bicycle ergometry test and the work incapacity of men 40 to 59 by Lisitsyn, V Iu, Dobo, S S, Glazunov, I S

“…The purpose of the investigation was to study the relationship between indicators of the bicycle ergometry test and temporary disability degree in males aged…”
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Correlation of major risk factors and physical tolerance in healthy controls and in patients with ischemic heart disease by Gromov, V L, Dobo, S S, Chazova, L V

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The effect of work processes and apportioned physical load on heart activity of healthy workers on the basis of radioelectrocardiographic data by Iazburskis, B I, Feskin, I P, Dobo, S S

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Study of cortical-subcortical dysfunction in arterial hypertension with associated disorders by means of induced hyperglycemia by MOGA, A, DOBO, S, HOROVITZ, V, ROTA, L, RUSU, M

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Development of methodical principles and approval of new forms of contact with school children (ages 12-13 years) in carrying out preventive measures (results of a pilot study) by Mukhamedzhanova, R F, Suslova, E A, Gusev, G V, Chazova, L V, Dobo, S S

“…The results of the screening and 1-year follow-up of pupils from two Moscow schools of general education (Moscow secondary schools) are presented. The program…”
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Bicycle ergometry test results in persons with ischemic heart disease detected in mass screening by Balavadze, M B, Chazova, L V, Dobo, S S, Gromov, V L

“…Bicycle ergometry in 40-59 year-old male patients with coronary heart disease, identified during mass prophylactic examination on the basis of epidemiological…”
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Interrelation of the risk factors and physical load tolerance based on bicycle ergometry data by Gromov, V L, Dobo, S S, Balavadze, M B, Shashnov, S A

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Use of the treadmill maximum exercise test in school children by Dobo, S S, Tubol, I B, Zinenko, G M, Likov, A F

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