Search Results - "Dobie, R."

Resolving the fibrotic niche of human liver cirrhosis at single-cell level by Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., Taylor, R. S., Efremova, M., Vento-Tormo, R., Carragher, N. O., Kendall, T. J., Fallowfield, J. A., Harrison, E. M., Mole, D. J., Wigmore, S. J., Newsome, P. N., Weston, C. J., Iredale, J. P., Tacke, F., Pollard, J. W., Ponting, C. P., Marioni, J. C., Teichmann, S. A., Henderson, N. C.

“…Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies…”
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αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis by Murray, I. R., Gonzalez, Z. N., Baily, J., Dobie, R., Wallace, R. J., Mackinnon, A. C., Smith, J. R., Greenhalgh, S. N., Thompson, A. I., Conroy, K. P., Griggs, D. W., Ruminski, P. G., Gray, G. A., Singh, M., Campbell, M. A., Kendall, T. J., Dai, J., Li, Y., Iredale, J. P., Simpson, H., Huard, J., Péault, B., Henderson, N. C.

“…Mesenchymal cells expressing platelet-derived growth factor receptor beta (PDGFRβ) are known to be important in fibrosis of organs such as the liver and…”
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Growth and the Growth Hormone-Insulin Like Growth Factor 1 Axis in Children With Chronic Inflammation: Current Evidence, Gaps in Knowledge, and Future Directions by Wong, S. C, Dobie, R, Altowati, M. A, Werther, G. A, Farquharson, C, Ahmed, S. F

“…Growth failure is frequently encountered in children with chronic inflammatory conditions like juvenile idiopathic arthritis, inflammatory bowel disease, and…”
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A Review of Randomized Clinical Trials in Tinnitus by Dobie, Robert A.

“…Objectives: Review reports of randomized clinical trials (RCTs) in tinnitus to identify well‐established treatments, promising developments, and opportunities…”
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Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2−/− mice by Dobie, R, MacRae, V E, Huesa, C, van't Hof, R, Ahmed, S F, Farquharson, C

“…The suppressor of cytokine signalling (Socs2−/−)-knockout mouse is characterised by an overgrowth phenotype due to enhanced GH signalling. The objective of…”
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Handbook of Oil Industry Terms & Phrases by Langenkamp, R.D

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OR01-2 Increased GH signalling independent of IGF-1 is associated with increased bone strength in the SOCS2 knockout mouse by Dobie, R, Huesa, C, Hof, R.J. van't, MacRae, V.E, Ahmed, S.F, Farquharson, C

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Estimating noise-induced permanent threshold shift from audiometric shape: The ISO-1999 model by Dobie, R

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445 (PB433): Identifying Disease Relevant Macrophage Subtypes in vitro using RNASequencing Transcriptome Profiling by Gurney, M., Turner, D., Dobie, R., McPherson, R., Gooding, H., Rzepecka, J.

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A comparison of t test, F test, and coherence methods of detecting steady-state auditory-evoked potentials, distortion-product otoacoustic emissions, or other sinusoids by Dobie, R A, Wilson, M J

“…Sinusoids in background noise can conveniently be detected using unsegmented power spectra, comparing power at the signal frequency to average power at several…”
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What Happens to the Iraqi Oil?: Thoughts on Some Significant, Unexamined International Legal Questions Regarding Occupation of Oil Fields by Langenkamp, R Dobie, Zedalis, Rex J

“…Possible US and allied occupation of Iraqi oil fields following any military action against Saddam Hussein would raise a variety of interesting legal issues…”
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Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis by Dobie, Ross, Wilson-Kanamori, John R., Henderson, Beth E.P., Smith, James R., Matchett, Kylie P., Portman, Jordan R., Wallenborg, Karolina, Picelli, Simone, Zagorska, Anna, Pendem, Swetha V., Hudson, Thomas E., Wu, Minnie M., Budas, Grant R., Breckenridge, David G., Harrison, Ewen M., Mole, Damian J., Wigmore, Stephen J., Ramachandran, Prakash, Ponting, Chris P., Teichmann, Sarah A., Marioni, John C., Henderson, Neil C.

“…Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells…”
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Single Cell Sequencing Reveals Heterogeneity Of Adventitial Mesenchymal Cells In Healthy Mice by van Kuijk, K., Dobie, R., Ramachandran, P., Taylor, R., Baker, A., Henderson, N., Sluimer, J.

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Partial myeloid inhibition of key glycolytic enzyme PFKFB3 increases hepatic steatosis and inflammation, but does not affect atherosclerosis by Tillie, R., De Bruijn, J., Dobie, R., Perales-Patón, J., Van Kuijk, K., Gijbels, M., Temmerman, L., Ghosheh, Y., Goossens, G., Carmeliet, P., Ley, K., Henderson, N., Saez-Rodriguez, J., Wouters, K., Sluimer, J.

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Amplitude-modulation following response (AMFR): effects of modulation rate, carrier frequency, age, and state by Levi, E C, Folsom, R C, Dobie, R A

“…Scalp responses to continuous amplitude-modulated (AM) tones were recorded from adults and 1-month-old infants. The amplitude-modulation following (or…”
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Analysis of Auditory Evoked Potentials by Magnitude-Squared Coherence by Dobie, Robert A, Wilson, Michael J

“…Evoked potentials are usually analyzed in the time domain (voltage versus time). The most familiar frequency-domain measure, the power spectral density…”
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Occupational Noise-Induced Hearing Loss by Kirchner, D. Bruce, Evenson, Eric, Dobie, Robert A., Rabinowitz, Peter, Crawford, James, Kopke, Richard, Hudson, Warner

“…Noise-induced hearing loss (NIHL) continues to be one of the most prevalent occupational conditions and occurs across a wide spectrum of industries…”
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Impact of a laryngectomy on quality of life: perspective of the patient versus that of the health care provider by Otto, R A, Dobie, R A, Lawrence, V, Sakai, C

“…This study retrospectively assesses the impact of laryngectomy on the quality of life of 46 patients as compared to the perception of the impact of…”
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Human and murine single-cell RNA-sequencing reveal fibroblast heterogeneity in healthy and diseased vasculature and differential regulation by ageing and serum cholesterol by Van Kuijk, K., Mccracken, I., Tillie, R., Asselberghs, S., Kheder, D., Muitjens, S., Jin, H., Taylor, R., Schreur, R. Wichers, Kuppe, C., Dobie, R., Ramachandran, P., Gijbels, M., Temmerman, L., Kirkwood, P., Luyten, J., Li, Y., Noels, H., Goossens, P., Wilson-Kanamori, J., Schurgers, L., Shen, Y., Mees, B., Biessen, E., Henderson, N., Kramann, R., Baker, A., Sluimer, J.

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Low-level steady-state auditory evoked potentials: effects of rate and sedation on detectability by Dobie, R A, Wilson, M J

“…Steady-state auditory evoked potentials (SSAEPs) in alert adults are most detectable at stimulus or modulation rates of about 40 Hz. Sedation reduces the…”
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