Search Results - "Dobi, Krisztina"

  • Showing 1 - 10 results of 10
Refine Results
  1. 1

    Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo by Stern, Noa, Gacs, Alexandra, Tátrai, Enikő, Flachner, Beáta, Hajdú, István, Dobi, Krisztina, Bágyi, István, Dormán, György, Lőrincz, Zsolt, Cseh, Sándor, Kígyós, Attila, Tóvári, József, Goldblum, Amiram

    “…Alzheimer’s disease (AD) is a complex and widespread condition, still not fully understood and with no cure yet. Amyloid beta (Aβ) peptide is suspected to be a…”
    Get full text
    Journal Article
  2. 2
  3. 3

    Robust Recombinant Expression of Human Placental Ribonuclease Inhibitor in Insect Cells by Flachner, Beáta, Dobi, Krisztina, Benedek, Anett, Cseh, Sándor, Lőrincz, Zsolt, Hajdú, István

    Published in Biomolecules (Basel, Switzerland) (08-02-2022)
    “…Ribonuclease inhibitors (RIs) are an indispensable biotechnological tool for the detection and manipulation of RNA. Nowadays, due to the outbreak of COVID-19,…”
    Get full text
    Journal Article
  4. 4

    Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening by Szaszkó, Mária, Hajdú, István, Flachner, Beáta, Dobi, Krisztina, Magyar, Csaba, Simon, István, Lőrincz, Zsolt, Kapui, Zoltán, Pázmány, Tamás, Cseh, Sándor, Dormán, György

    Published in Molecular diversity (01-02-2017)
    “…A glutaminyl cyclase (QC) fragment library was in silico selected by disconnection of the structure of known QC inhibitors and by lead-like 2D virtual…”
    Get full text
    Journal Article
  5. 5
  6. 6

    Monoclonal antibody proteomics: Use of antibody mimotope displaying phages and the relevant synthetic peptides for mAb scouting by Hajdú, István, Flachner, Beáta, Bognár, Melinda, Végh, Barbara M, Dobi, Krisztina, Lőrincz, Zsolt, Lázár, József, Cseh, Sándor, Takács, László, Kurucz, István

    Published in Immunology letters (01-08-2014)
    “…Highlights • A workflow for selecting monoclonal antibodies for biomarker assays was devised. • Large mAB libraries where cognate antigens are not known were…”
    Get full text
    Journal Article
  7. 7
  8. 8
  9. 9

    Rapid in silico selection of an MCHR1 antagonists’ focused library from multi-million compounds’ repositories: biological evaluation by Flachner, Beáta, Tömöri, Tünde, Hajdú, István, Dobi, Krisztina, Lőrincz, Zsolt, Cseh, Sándor, Dormán, György

    Published in Medicinal chemistry research (01-03-2014)
    “…Target-focused libraries can be rapidly selected by 2D virtual screening methods from multimillion compounds’ databases if structures of active compounds are…”
    Get full text
    Journal Article
  10. 10

    Selection of a melanine concentrating hormone receptor-1 (MCHR1) antagonists' focused library and its biological screening with AequoScreen by Flachner, Beáta, Hajdú, István, Dobi, Krisztina, Lorincz, Zsolt, Cseh, Sándor, Dormán, György

    Published in Acta pharmaceutica Hungarica (2013)
    “…Target focused libraries can be rapidly selected by 2D virtual screening methods from multimillion compounds' repositories if structures of active compounds…”
    Get more information
    Journal Article