Search Results - "Dobbins, David E"
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Mutation of macrophage colony stimulating factor ( Csf1) causes osteopetrosis in the tl rat
Published in Biochemical and biophysical research communications (28-06-2002)“…Osteopetrosis results from a heterogeneous group of congenital bone diseases that display inadequate osteoclastic bone resorption. We recently mapped tl…”
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Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs : A model for pseudoallergic cardiopulmonary reactions to liposomes : Role of complement and inhibition by soluble CR1 and anti-C5a antibody
Published in Circulation (New York, N.Y.) (04-05-1999)“…Intravenous administration of some liposomal drugs can trigger immediate hypersensitivity reactions that include symptoms of cardiopulmonary distress. The…”
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Receptor mechanisms of prenodal lymphatic constriction by dopamine
Published in Regulatory peptides (15-06-2003)“…It has been proposed that alterations in lymphatic smooth muscle activity significantly impact lymphatic function. Numerous endogenous vasoactive agents are…”
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Localization of the Mutation Responsible for Osteopetrosis in the op Rat to a 1.5‐cM Genetic Interval on Rat Chromosome 10: Identification of Positional Candidate Genes by Radiation Hybrid Mapping
Published in Journal of bone and mineral research (01-10-2002)“…Osteopetrosis is caused by a heterogenous group of bone diseases that result in an increase in skeletal mass because of inadequate osteoclastic bone…”
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Failed bone homeostasis in the op rat is not due to a mutation in the coding region of the Prss34 gene
Published in The FASEB journal (01-04-2011)“…The spontaneously occurring mutation in op rats produces an animal with severe osteopetrosis due to inadequate osteoclastic bone resorption. This mutation has…”
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Evidence that the mutation responsible for osteopetrosis in the op rat is not contained within the coding region of the Tbl3 gene
Published in The FASEB journal (01-04-2010)“…The spontaneously occurring mutation in op rats produces an animal with severe osteopetrosis. The op mutation has been localized to a 0.51 cM portion of rat…”
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Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb
Published in The American journal of physiology (01-02-1998)“…Numerous endogenous vasoactive agents have been shown to cause lymphatic smooth muscle contraction. In this study, we assessed the ability of serotonin (5-HT)…”
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The osteopetrosis seen in the op rat is not the result of a mutation within the coding region of the Mcpt7 gene
Published in The FASEB journal (01-04-2009)“…Abstract only The spontaneously occurring mutation in op rats produces an animal with severe osteopetrosis. Production of affected F 2 animals with recombinant…”
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Application of interval haplotype analysis facilitates efficient mapping of the mutation causing osteopetrosis in tl rats
Published in Mammalian genome (01-06-2002)Get full text
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Failure of osteoclastic bone resorption in the op rat is not due to a mutation within the coding region of the Abca3 gene
Published in The FASEB journal (01-03-2008)“…Abstract only The spontaneous mutation in op rats produces an animal with severe osteopetrosis. This mutation has been localized to a 0.51 cM portion of RNO10…”
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The mutation causing osteopetrosis in the op rat does not reside within the coding sequence of the Traf7 gene
Published in The FASEB journal (2007)“…The spontaneously occurring mutation in op rats produces an animal with severe osteopetrosis. Production of affected F2 animals with recombinant events has…”
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12
Neuropeptide modulation of lymphatic smooth muscle tone in the canine forelimb
Published in Mediators of Inflammation (1992)“…NEUROKININ A and B are putative inflammatory mediators. We assessed their ability to alter prenodal lymphatic resistance. Intralymphatic neurokinin A (3.0x…”
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Evidence that the mutation responsible for osteopetrosis in the op rat is not contained within the coding region of the Slc9a3r2 gene
Published in The FASEB journal (2007)“…The spontaneously occurring mutation in op rats produces an animal with severe osteopetrosis. Production of affected F2 animals with recombinant events has…”
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Modulation of multiple experimental arthritis models by collagen‐induced arthritis quantitative trait loci isolated in congenic rat lines: Different effects of non–major histocompatibility complex quantitative trait loci in males and females
Published in Arthritis and rheumatism (01-08-2002)“…Objective Collagen‐induced arthritis (CIA) is a model of inflammatory arthritis with many similarities to rheumatoid arthritis (RA). We previously mapped in F2…”
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Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant‐induced arthritis in monocongenic and polycongenic rats: Identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci
Published in Arthritis and rheumatism (01-04-2002)“…Objective To evaluate the regulatory potential of genetic loci controlling Mycobacterium butyricum adjuvant‐induced arthritis (Mbt‐AIA) using mono‐ and…”
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Genetic dissection of collagen-induced arthritis in Chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences
Published in Immunogenetics (New York) (01-09-2000)“…Rat Chromosome 10 (RNO10) harbors Cia5, a non-MHC quantitative trait locus (QTL) that regulates the severity of type II collagen-induced arthritis (CIA) in…”
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Polymorphisms of the tumor necrosis factor receptor type 1 locus among autoimmune susceptible and resistant inbred rat strains
Published in Immunogenetics (New York) (01-07-2001)“…Among inbred rat strains, susceptibility to and severity of autoimmune diseases varies dramatically. For example, DA/Bkl (DA), LEW/NHsd (LEW), and BB/(DR)/Wor…”
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Receptor mechanisms of bradykinin-mediated activation of prenodal lymphatic smooth muscle
Published in Regulatory peptides (24-04-1998)“…We have previously shown that several endogenous vasoactive agents constrict prenodal lymph vessels in the canine forelimb. In this study, we assessed the…”
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Endothelin-mediated constriction of prenodal lymphatic vessels in the canine forelimb
Published in Regulatory peptides (23-07-1991)“…Endothelin is a 21 amino acid peptide which is produced by the vascular endothelium and is believed to be the mediator of endothelium-dependent…”
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Effects of amino acid isomers on canine renal hemodynamics
Published in The American journal of physiology (01-04-1990)“…The major objective of this study was to ascertain whether the renal hemodynamic response to amino acid infusion in dogs is stereospecific. To test this…”
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