Search Results - "Dobbelstein, Christiane"
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Reduced-intensity, risk factor–stratified immunosuppression for acquired hemophilia A: single-center observational study
Published in Annals of hematology (01-09-2020)“…Immunosuppressive therapy (IST) is administered to patients with acquired hemophilia A (AHA) to eradicate autoantibodies against coagulation factor VIII…”
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Immunosuppressive Therapy for Patients With Myelodysplastic Syndrome: A Prospective Randomized Multicenter Phase III Trial Comparing Antithymocyte Globulin Plus Cyclosporine With Best Supportive Care—SAKK 33/99
Published in Journal of clinical oncology (20-01-2011)“…Immunosuppressive treatment is reported to improve cytopenia in some patients with myelodysplastic syndrome (MDS). Combined antithymocyte globulin (ATG) and…”
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Long-Term Outcomes after Vaccine-Induced Thrombotic Thrombocytopenia
Published in Viruses (01-08-2022)“…Vaccine-induced thrombotic thrombocytopenia (VITT), or thrombosis with thrombocytopenia syndrome (TTS), is a rare but serious complication of adenovirus-based…”
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Anti–factor VIII IgA as a potential marker of poor prognosis in acquired hemophilia A: results from the GTH-AH 01/2010 study
Published in Blood (12-05-2016)“…Neutralizing autoantibodies against factor VIII (FVIII), also called FVIII inhibitors, are the cause of acquired hemophilia A (AHA). They are quantified in the…”
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Immunosuppressive therapy for myelodysplastic syndromes
Published in Current pharmaceutical design (01-07-2012)“…Myelodysplastic syndromes (MDS) comprise a heterogeneous group of diseases characterized by bone marrow failure, marrow dysplasia, and a tendency to evolve to…”
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Comorbidity and adverse events in acquired hemophilia A: data from the GTH-AHA-EMI study
Published in Research and practice in thrombosis and haemostasis (01-10-2024)“…Persons with acquired hemophilia A are often older and suffer from comorbidity or frailty. Little is known about the impact on clinically relevant outcomes of…”
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Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study
Published in The Lancet. Haematology (01-11-2023)“…Acquired haemophilia A is caused by neutralising autoantibodies against coagulation factor VIII, leading to severe bleeding. Standard treatment involves…”
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Factor VIII Activity and Risk of Bleeding in Acquired Hemophilia a: Results from the Gth-AH 01/2010 Study
Published in Blood (08-12-2017)“…Background: Acquired hemophilia A (AHA) is a serious bleeding disorder characterized by the formation of autoantibodies against coagulation factor VIII…”
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Prognostic Impact Of a Newly Defined Structurally Complex Karyotype In Patients With AML and MDS After Allogeneic Stem Cell Transplantation
Published in Blood (15-11-2013)“…Allogeneic stem cell transplantation (SCT) is a potentially curative treatment for patients with high-risk acute myeloid leukemia (AML) and myelodysplastic…”
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Proteomic Pattern-Based Risk Stratification of Outcome Shows Significant Higher Accuracy Compared to HCT-CI in Patients with AML and MDS
Published in Blood (18-11-2011)“…Abstract 4128 Allogeneic stem cell transplantation (SCT) is an established treatment for many severe disorders of hematopoiesis. Although SCT has considerable…”
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Prospective Validation of a Chronic GvHD-Specific Proteome Pattern (cGvHD-MS14) Post Allogeneic Hematopoietic Stem Cell Transplantation
Published in Blood (18-11-2011)“…Abstract 1970 Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment for many hematologic malignancies and non-malignant…”
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Lower Relapse Incidence and Relapse Mortality in Patients Transplanted from a Younger Sibling in HLA-Identical Stem Cell Transplantation: Does Microchimerism Matter?
Published in Blood (16-11-2008)“…Background: There is some evidence that microchimerism plays a role in outcome of HLA-identical stem cell transplantation (SCT). Evaluation of primacy of birth…”
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Immunosuppressive treatment strategies in low-risk MDS
Published in Cancer treatment reviews (2007)“…Summary Ineffective haematopoiesis with peripheral cytopenias despite normo- or hypercellular bone marrow is the hallmark of the myelodysplastic syndromes…”
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Immunosuppression for Patients with Low and Intermediate Risk Myelodysplastic Syndrome: A Prospective Randomized Multicenter Trial Comparing Antithymocyte Globulin + Cyclosporine with Best Supportive Care: SAKK 33/99
Published in Blood (16-11-2007)“…Immunosuppressive treatment has been reported to improve cytopenia in some patients with myelodysplastic syndrome (MDS). The combined use of anti-thymocyte…”
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Atypical Presentations of EBV Reactivation and EBV-Associated PTLD Post-HSCT: Implication for Routine EBV Surveillance after Allogeneic HSCT?
Published in Blood (16-11-2005)“…Allogeneic hematopoietic stem cell transplantation (HSCT), an effective treatment for leukemia and other disorders, produces profound immune deficiency in the…”
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Continued Low-Dose Decitabine (DAC) Is an Active First-Line Treatment of Older AML Patients: First Results of a Multicenter Phase II Study
Published in Blood (16-11-2005)“…Background: Few therapeutic options exist for older AML patients (pts) in whom induction chemotherapy is not feasible. Encouraged by the marked activity and…”
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Birth Order and Transplantation Outcome in HLA-Identical Sibling Stem Cell Transplantation: An Analysis on Behalf of the Center for International Blood and Marrow Transplantation
Published in Biology of blood and marrow transplantation (01-05-2013)“…Abstract Allogeneic stem cell transplantation (SCT) is the most effective treatment option for many hematologic malignancies, but graft-versus-host disease…”
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