Search Results - "Dobashi, Yasuo"

Highly Enantioselective Synthesis of Atropisomeric Anilide Derivatives through Catalytic Asymmetric N-Arylation:  Conformational Analysis and Application to Asymmetric Enolate Chemistry by Kitagawa, Osamu, Yoshikawa, Masatoshi, Tanabe, Hajime, Morita, Tomofumi, Takahashi, Masashi, Dobashi, Yasuo, Taguchi, Takeo

“…In the presence of (R)-DTBM-SEGPHOS−Pd(OAc)2 catalyst, N-arylation (aromatic amination) of various o-tert-butylanilides with p-iodonitrobenzene proceeds with…”
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The synthesis of optically active N-C axially chiral tetrahydroquinoline and its response to an acid-accelerated molecular rotor by Suzuki, Yuya, Kageyama, Masato, Morisawa, Ryuichi, Dobashi, Yasuo, Hasegawa, Hiroshi, Yokojima, Satoshi, Kitagawa, Osamu

“…Optically active atropisomeric N-(2,5-di-tert-butylphenyl)-1,2,3,4-tetrahydroquinoline with an N-C chiral axis was prepared via a catalytic enantioselective…”
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Relationship between rotational barriers and structures in N–C axially chiral 3,4-dihydroquinolin-2-one and 3,4-dihydrobenzoquinolin-2-one by Suzuki, Yuya, Takahashi, Isao, Dobashi, Yasuo, Hasegawa, Hiroshi, Roussel, Christian, Kitagawa, Osamu

“…[Display omitted] The rotational barrier around the N–C chiral axis in N-(2-tert-butylphenyl)-3,4-dihydrobenzoquinolin-2-one was found to be 6kcal/mol lower…”
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Intramolecular Diels–Alder reaction of N-allyl 2-furoyl amides: effect of steric strain and amide rotational isomerism by Nakamura, Masashi, Takahashi, Isao, Yamada, Shunsuke, Dobashi, Yasuo, Kitagawa, Osamu

“…Intramolecular Diels–Alder reactions of various N-allyl 2-furoyl amides with different substituents on the nitrogen atom were investigated. The reaction of…”
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Studies on rotational barriers of N–C axially chiral compounds: increase in the rotational barrier by aromatization by Suzumura, Naomi, Kageyama, Masato, Kamimura, Daichi, Inagaki, Takahiro, Dobashi, Yasuo, Hasegawa, Hiroshi, Fukaya, Haruhiko, Kitagawa, Osamu

“…The rotational barriers in axially chiral quinolin-2-one and quinazolin-2-one possessing N-(ortho-tert-butyl)phenyl group were found to significantly increase…”
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2-(Pyridinium-1-yl)-1,1-bis(triflyl)ethanides: structural behaviour and availability as bis(triflyl)ethylating reagents by Yanai, Hikaru, Takahashi, Yoichi, Fukaya, Haruhiko, Dobashi, Yasuo, Matsumoto, Takashi

“…Stable and easy-to-handle zwitterions containing carbanion and pyridinium moieties were synthesized, and their structural studies by both X-ray crystallography…”
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Chemical Bonding in Polarised Push–Pull Ethylenes by Yanai, Hikaru, Suzuki, Takumi, Kleemiss, Florian, Fukaya, Haruhiko, Dobashi, Yasuo, Malaspina, Lorraine A., Grabowsky, Simon, Matsumoto, Takashi

“…1,1‐Diamino‐2,2‐bis(triflyl)ethylenes with both twisted and planar structures around the partial “C=C” bond were synthesised. Bonding properties in these…”
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Development of new mixing method of Busulfex injection for the purpose of improvement of medical safety method: the prefilled syringe method by Senoo, Makoto, Tajika, Kenji, Shimizu, Hisanori, Hamada, Masaki, Dobashi, Yasuo, Dobashi, Akira, Dan, Kazuo, Katayama, Shiro

“…Busulfex is a new type of busulfan which can be administered intravenously. Usually it is administered over 2 hours every 6 hours. Its injection should be…”
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A New Twisted Dual Hydrogen Bond Acceptor Featuring Amidine Functionality for Chiral Recognition: A High Level of Enantioselection of Diol Derivatives by Dobashi, Yasuo, Kobayashi, Kiyotaka, Dobashi, Akira

“…The C 2 amidine derivative ( S,S)- 1, as a twisted chiral dual acceptor for hydrogen bonding, was designed and synthesized. Enantioselective binding between (…”
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Chiral recognition of 1,1′-bi-2-naphthol enantiomers by twisted amidine derivatives: Rational design of a highly enantioselective receptor by Dobashi, Yasuo, Kobayashi, Kiyotaka, Sato, Norihisa, Dobashi, Akira

“…Clarification of the molecular structures of diastereomeric complexes relevant to the enantioselective dual N···HO binding between the chiral C 2 amidine…”
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Highly Selective Stereodivergent Synthesis of Separable Amide Rotamers, by Using Pd Chemistry, and Their Thermodynamic Behavior by Ototake, Nobutaka, Nakamura, Masashi, Dobashi, Yasuo, Fukaya, Haruhiko, Kitagawa, Osamu

“…Going separate ways: By using π‐allyl–palladium chemistry (path A) and PdII‐catalyzed Claisen chemistry (path B), a highly selective stereodivergent synthesis…”
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医療安全を指向したプレフィルドシリンジ化によるブスルフェクス®注の混合調製方法の開発 by 瀬尾, 誠, 田近, 賢二, 清水, 久範, 浜田, 真向, 土橋, 保夫, 土橋, 朗, 檀, 和夫, 片山, 志郎

“…「緒言」高用量ブスルファンは同種造血幹細胞移植や自家造血幹細胞移植の前治療に用いられている. 従来経口投与が行われてきたが, 1,2)消化管からの吸収に個人差があり, 至適血中濃度域から逸脱した場合の生着不全や再発, 臓器障害発症が懸念されていた. 3,4)2006年10月, ブスルファンを主成分とする注射液,…”
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Chemical Bonding in Polarised Push–Pull Ethylenes by Yanai, Hikaru, Suzuki, Takumi, Kleemiss, Florian, Fukaya, Haruhiko, Dobashi, Yasuo, Malaspina, Lorraine A., Grabowsky, Simon, Matsumoto, Takashi

“…1,1‐Diamino‐2,2‐bis(triflyl)ethylenes with both twisted and planar structures around the partial “C=C” bond were synthesised. Bonding properties in these…”
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New, rational molecular design for chiral recognition involving application of dual hydrogen bond association by Dobashi, Yasuo, Dobashi, Akira, Ochiai, Hisao, Hara, Shoji

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Catalytic Asymmetric Synthesis of Vicinal Diamine Derivatives through Enantioselective N-Allylation Using Chiral π-Allyl Pd-Catalyst by Kitagawa, Osamu, Yotsumoto, Kanako, Kohriyama, Mitsuteru, Dobashi, Yasuo, Taguchi, Takeo

“…N-Monoallylation of meso-vicinal diamine bistrisylamides using a chiral π-allyl-Pd catalyst proceeded in an enantioselective manner (up to 90% ee) to give…”
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Development of New Mixing Method of Busulfex® Injecton for the Purpose of Improvement of Medical Safety Method; The Prefilled Syringe Method by SENOO, Makoto, TAJIKA, Kenji, SHIMIZU, Hisanori, HAMADA, Masaki, DOBASHI, Yasuo, DOBASHI, Akira, DAN, Kazuo, KATAYAMA, Shiro

“…Busulfex®is a new type of busulfan which can be administered intravenously. Usually it is administered over 2 hours every 6 hours. Its injection should be…”
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Enantiomeric Separation with Sodium Dodecanoyl-L-amino Acidate Micelles and Poly(sodium (10-undecenoyl)-L-valinate) by Electrokinetic Chromatography by Dobashi, Akira, Hamada, Masaki, Dobashi, Yasuo, Yamaguchi, Junko

“…A micelle-like polymer is prepared by photopolymerization of a vinyl group-terminated sodium (10-undecenoyl)-L-valinate. Evidence shows that it exhibits…”
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An automated analyzer for methylated arginines in rat plasma by high-performance liquid chromatography with post-column fluorescence reaction by Dobashi, Yasuo, Santa, Tomofumi, Nakagomi, Kazuya, Imai, Kazuhiro

“…A fully automated analyzer for methylated L-arginine metabolites [N,N-dimethyl-L-arginine (ADMA), N-methylarginine (NMMA) and N,N'-dimethyl-L-arginine (SDMA)]…”
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Hydrozirconation of alkenyloxirane derivatives: Preparation of cycloalkylmethanols by Harada, Susumu, Kowase, Noboru, Tabuchi, Nobuhito, Taguchi, Takeo, Dobashi, Yasuo, Dobashi, Akira, Hanzawa, Yuji

“…Cyclopentyl and cyclopropylmethanol derivatives were efficiently prepared through a chemoselective hydrozirconation reaction of (1-butenyl)oxirane and…”
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A Programmed Flow Preparation System incorporating Droplet Current Distribution Technique by HARA, SHOJI, OKA, KITARO, DOBASHI, YASUO, OHKUMA, TOSHIKAZU

“…A system for programmed flow preparation was developed by carrying the usual batch process into flow manipulations. All processes in preparative chemistry,…”
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