Search Results - "Doan, Ryan A"

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  1. 1

    Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice by Geisler, Stefanie, Doan, Ryan A, Strickland, Amy, Huang, Xin, Milbrandt, Jeffrey, DiAntonio, Aaron

    Published in Brain (London, England : 1878) (01-12-2016)
    “…Peripheral polyneuropathy is a common and dose-limiting side effect of many important chemotherapeutic agents. Most such neuropathies are characterized by…”
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  2. 2

    Gene therapy targeting SARM1 blocks pathological axon degeneration in mice by Geisler, Stefanie, Huang, Shay X, Strickland, Amy, Doan, Ryan A, Summers, Daniel W, Mao, Xianrong, Park, Jiwoong, DiAntonio, Aaron, Milbrandt, Jeffrey

    Published in The Journal of experimental medicine (04-02-2019)
    “…Axonal degeneration (AxD) following nerve injury, chemotherapy, and in several neurological disorders is an active process driven by SARM1, an injury-activated…”
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  3. 3

    Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program by Geisler, Stefanie, Doan, Ryan A, Cheng, Galen C, Cetinkaya-Fisgin, Aysel, Huang, Shay X, Höke, Ahmet, Milbrandt, Jeffrey, DiAntonio, Aaron

    Published in JCI insight (05-09-2019)
    “…Chemotherapy-induced peripheral neuropathy is one of the most prevalent dose-limiting toxicities of anticancer therapy. Development of effective therapies to…”
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  4. 4

    TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance by Bhattacharya, Martha R C, Geisler, Stefanie, Pittman, Sara K, Doan, Ryan A, Weihl, Conrad C, Milbrandt, Jeffrey, DiAntonio, Aaron

    Published in The Journal of neuroscience (27-04-2016)
    “…Complex nervous systems achieve proper connectivity during development and must maintain these connections throughout life. The processes of axon and synaptic…”
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  5. 5

    Glia in the skin activate pain responses by Doan, Ryan A, Monk, Kelly R

    “…A newly discovered cell type forms a network that senses painful stimuli The ability to rapidly perceive and react to damaging stimuli is essential for…”
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