Search Results - "Doan, Peter E"

Internal dynamics of a supramolecular nanofibre by Ortony, Julia H., Newcomb, Christina J., Matson, John B., Palmer, Liam C., Doan, Peter E., Hoffman, Brian M., Stupp, Samuel I.

“…Variations in the internal conformational dynamics of supramolecular nanostructures may be important for their function, yet such dynamics have been difficult…”
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Oxygen and the Copper Chaperone CCS Regulate Posttranslational Activation of Cu,Zn Superoxide Dismutase by Brown, Nina M., Torres, Andrew S., Doan, Peter E., O'Halloran, Thomas V., Lippard, Stephen J.

“…Oxidative stress leads to the up-regulation of many antioxidant enzymes including Cu,Zn superoxide dismutase (SOD1) via transcriptional mechanisms; however,…”
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Purified Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath) Is a Dimer with Both Mononuclear Copper and a Copper-Containing Cluster by Lieberman, Raquel L., Shrestha, Deepak B., Doan, Peter E., Hoffman, Brian M., Stemmler, Timothy L., Rosenzweig, Amy C.

“…Particulate methane monooxygenase (pMMO) is a membrane-bound enzyme that catalyzes the oxidation of methane to methanol in methanotropic bacteria…”
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Terminal Hydride Complex of High-Spin Mn by Drena, Alex, Fraker, Addison, Thompson, Niklas B., Doan, Peter E., Hoffman, Brian M., McSkimming, Alex

“…The iron–molybdenum cofactor of nitrogenase (FeMoco) catalyzes fixation of N2 via Fe hydride intermediates. Our understanding of these species has relied…”
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Correction to “Terminal Hydride Complex of High-Spin Mn” by Drena, Alex, Fraker, Addison, Thompson, Niklas B., Doan, Peter E., Hoffman, Brian M., McSkimming, Alex

“…Correction to “Terminal Hydride Complex of High-Spin Mn”…”
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Coordination of the Copper Centers in Particulate Methane Monooxygenase: Comparison between Methanotrophs and Characterization of the Cu C Site by EPR and ENDOR Spectroscopies by Jodts, Richard J, Ross, Matthew O, Koo, Christopher W, Doan, Peter E, Rosenzweig, Amy C, Hoffman, Brian M

“…In nature, methane is oxidized to methanol by two enzymes, the iron-dependent soluble methane monooxygenase (sMMO) and the copper-dependent particulate MMO…”
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The Challenges and Opportunities of High-Spin Mn(II) EPR and ENDOR by Doan, Peter E., Drena, Alex, Sharma, Ajay, Hoffman, Brian M.

“…We examine the electron paramagnetic resonance (EPR) and electron-nuclear double resonance (ENDOR) spectroscopy of three quite distinct high-spin Mn(II)…”
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The Soybean Lipoxygenase–Substrate Complex: Correlation between the Properties of Tunneling-Ready States and ENDOR-Detected Structures of Ground States by Offenbacher, Adam R, Sharma, Ajay, Doan, Peter E, Klinman, Judith P, Hoffman, Brian M

“…Hydrogen tunneling in enzymatic C–H activation requires a dynamical sampling among ground-state enzyme–substrate (E–S) conformations, which transiently…”
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Initial Steps in Methanobactin Biosynthesis: Substrate Binding by the Mixed-Valent Diiron Enzyme MbnBC by Jodts, Richard J., Ho, Madeline B., Reyes, Reyvin M., Park, Yun Ji, Doan, Peter E., Rosenzweig, Amy C., Hoffman, Brian M.

“…The MbnBC enzyme complex converts cysteine residues in a peptide substrate, MbnA, to oxazolone/thioamide groups during the biosynthesis of copper chelator…”
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13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N‑Linked Glycosylated Lipoxygenase by Sharma, Ajay, Whittington, Chris, Jabed, Mohammed, Hill, S. Gage, Kostenko, Anastasiia, Yu, Tao, Li, Pengfei, Doan, Peter E., Hoffman, Brian M., Offenbacher, Adam R.

“…Lipoxygenase (LOX) enzymes produce important cell-signaling mediators, yet attempts to capture and characterize LOX–substrate complexes by X-ray…”
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13 C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme-Substrate Complex of an Active, N -Linked Glycosylated Lipoxygenase by Sharma, Ajay, Whittington, Chris, Jabed, Mohammed, Hill, S Gage, Kostenko, Anastasiia, Yu, Tao, Li, Pengfei, Doan, Peter E, Hoffman, Brian M, Offenbacher, Adam R

“…Lipoxygenase (LOX) enzymes produce important cell-signaling mediators, yet attempts to capture and characterize LOX-substrate complexes by X-ray…”
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Combining steady-state and dynamic methods for determining absolute signs of hyperfine interactions: Pulsed ENDOR Saturation and Recovery (PESTRE) by Doan, Peter E.

“…The underlying causes of asymmetric intensities in Davies pulsed ENDOR spectra that are associated with the signs of the hyperfine interaction are…”
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Coordination of the Copper Centers in Particulate Methane Monooxygenase: Comparison between Methanotrophs and Characterization of the CuC Site by EPR and ENDOR Spectroscopies by Jodts, Richard J, Ross, Matthew O, Koo, Christopher W, Doan, Peter E, Rosenzweig, Amy C, Hoffman, Brian M

“…In nature, methane is oxidized to methanol by two enzymes, the iron-dependent soluble methane monooxygenase (sMMO) and the copper-dependent particulate MMO…”
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Composition and Structure of the Inorganic Core of Relaxed Intermediate X(Y122F) of Escherichia coli Ribonucleotide Reductase by Doan, Peter E, Shanmugam, Muralidharan, Stubbe, JoAnne, Hoffman, Brian M

“…Activation of the diferrous center of the β2 (R2) subunit of the class 1a Escherichia coli ribonucleotide reductases by reaction with O2 followed by…”
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A New Reaction for Improved Calibration of EPR Rapid-Freeze Quench Times: Kinetics of Ethylene Diamine Tetraacetate (EDTA) Transfer from Calcium(II) to Copper(II) by Schroeter, Abigail L., Yang, Hao, James, Christopher D., Hoffman, Brian M., Doan, Peter E.

“…The kinetics of the transfer of the chelate, ethylenediamine tetraacetate (EDTA), from Calcium(II ) to Copper(II) in imidazole (Im) buffers near neutral pH,…”
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Identification of Protonated Oxygenic Ligands of Ribonucleotide Reductase Intermediate X by Shanmugam, Muralidharan, Doan, Peter E., Lees, Nicholas S., Stubbe, JoAnne, Hoffman, Brian M.

“…We previously used a combination of continuous-wave (CW) and pulsed electron−nuclear double resonance (ENDOR) protocols to identify the types of protonated…”
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EPR and (57)Fe ENDOR investigation of 2Fe ferredoxins from Aquifex aeolicus by Cutsail, 3rd, George E, Doan, Peter E, Hoffman, Brian M, Meyer, Jacques, Telser, Joshua

“…We have employed EPR and a set of recently developed electron nuclear double resonance (ENDOR) spectroscopies to characterize a suite of [2Fe-2S] ferredoxin…”
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An Organometallic Intermediate during Alkyne Reduction by Nitrogenase by Lee, Hong-In, Igarashi, Robert Y, Laryukhin, Mikhail, Doan, Peter E, Dos Santos, Patricia C, Dean, Dennis R, Seefeldt, Lance C, Hoffman, Brian M

“…Nitrogenase is the metalloenzyme that catalyzes the nucleotide-dependent reduction of N2, as well as reduction of a variety of other triply bonded substrates,…”
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An Implicit TRIPLE Effect in Mims Pulsed ENDOR:  A Sensitive New Technique for Determining Signs of Hyperfine Couplings by Doan, Peter E, Nelson, Mark J, Jin, Haiyong, Hoffman, Brian M

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Simulating Suppression Effects in Pulsed ENDOR, and the ‘Hole in the Middle’ of Mims and Davies ENDOR Spectra by Doan, Peter E., Lees, Nicholas S., Shanmugam, Muralidharan, Hoffman, Brian M.

“…All pulsed electron-nuclear double resonance (ENDOR) techniques, and in particular the Mims and Davies sequences, suffer from detectability biases…”
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