Search Results - "Dörner, Bernd"

Synthesis and Small-Animal Positron Emission Tomography Evaluation of [11C]-Elacridar As a Radiotracer to Assess the Distribution of P-Glycoprotein at the Blood−Brain Barrier by Dörner, Bernd, Kuntner, Claudia, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Stundner, Gloria, Mairinger, Severin, Löscher, Wolfgang, Müller, Markus, Langer, Oliver, Erker, Thomas

“…With the aim to develop a positron emission tomography (PET) tracer to assess the distribution of P-glycoprotein (P-gp) at the blood−brain barrier (BBB) in…”
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Synthesis of New Acridone Derivatives, Inhibitors of NS3 Helicase, Which Efficiently and Specifically Inhibit Subgenomic HCV Replication by Stankiewicz-Drogoń, Anna, Dörner, Bernd, Erker, Thomas, Boguszewska-Chachulska, Anna M

“…A new goup of acridone derivatives, obtained by reaction of acridone-4-carboxylic acid derivatives with aromatic amines, was tested to determine the inhibitory…”
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Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor by Bauer, Florian, Kuntner, Claudia, Bankstahl, Jens P., Wanek, Thomas, Bankstahl, Marion, Stanek, Johann, Mairinger, Severin, Dörner, Bernd, Löscher, Wolfgang, Müller, Markus, Erker, Thomas, Langer, Oliver

“…The aim of this study was to develop a positron emission tomography (PET) tracer based on the dual P-glycoprotein (P-gp) breast cancer resistance protein…”
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Radiosynthesis and in vivo evaluation of 1-[ 18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein by Dörner, Bernd, Kuntner, Claudia, Bankstahl, Jens P., Wanek, Thomas, Bankstahl, Marion, Stanek, Johann, Müllauer, Julia, Bauer, Florian, Mairinger, Severin, Löscher, Wolfgang, Miller, Donald W., Chiba, Peter, Müller, Markus, Erker, Thomas, Langer, Oliver

“…Aim of this study was to label the potent dual P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor elacridar ( 1) with 18F to provide a…”
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Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11 C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)amino-carbonyl)-2-(quinoline-2-carbonylamino)benzoate by Mairinger, Severin, Langer, Oliver, Kuntner, Claudia, Wanek, Thomas, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Dörner, Bernd, Bauer, Florian, Baumgartner, Christoph, Löscher, Wolfgang, Erker, Thomas, Müller, Markus

“…Abstract Introduction The multidrug efflux transporter breast cancer resistance protein (BCRP) is highly expressed in the blood-brain barrier (BBB), where it…”
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Assessing cerebral P-glycoprotein expression and function with PET by combined [11C]inhibitor [11C]substrate scans by Kuntner, Claudia, Bankstahl, Jens P., Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Dörner, Bernd, Bauer, Florian, Mairinger, Severin, Erker, Thomas, Müller, Markus, Löscher, Wolfgang, Langer, Oliver

“…Purpose: Changes in expression and function of the multidrug efflux transporter P-glycoprotein (P-gp) at the blood-brain barrier are thought to be implicated…”
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Evaluation of [11C]elacridar and [11C]tariquidar in transporter knockout mice using small-animal PET by Kuntner, Claudia, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Dörner, Bernd, Bauer, Florian, Mairinger, Severin, Erker, Thomas, Müller, Markus, Löscher, Wolfgang, Langer, Oliver

“…Purpose: The radiolabelled non-competitive P-gp inhibitors [11C]elacridar and [11C]tariquidar are two new positron emission tomography (PET) tracers for…”
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Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11C]methyl 4-4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenylamino-carbonyl-2-(quinoline-2-carbonylamino)benzoate by MAIRINGER, Severin, LANGER, Oliver, LÖSCHER, Wolfgang, ERKER, Thomas, MÜLLER, Markus, KUNTNER, Claudia, WANEK, Thomas, BANKSTAHL, Jens P, BANKSTAHL, Marion, STANEK, Johann, DÖRNER, Bernd, BAUER, Florian, BAUMGARTNER, Christoph

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