Search Results - "Dmitry Bosykh"

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation by Komarova, Elena A, Gudkov, Andrei V, Strom, Evguenia, Sathe, Swati, Komarov, Pavel G, Chernova, Olga B, Pavlovska, Ivanda, Shyshynova, Inna, Bosykh, Dmitry A, Burdelya, Lyudmila G, Macklis, Roger M, Skaliter, Rami

“…p53-dependent apoptosis contributes to the side effects of cancer treatment, and genetic or pharmacological inhibition of p53 function can increase normal…”
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Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT by Gasparian, Alexander V, Burkhart, Catherine A, Purmal, Andrei A, Brodsky, Leonid, Pal, Mahadeb, Saranadasa, Madhi, Bosykh, Dmitry A, Commane, Mairead, Guryanova, Olga A, Pal, Srabani, Safina, Alfiya, Sviridov, Sergey, Koman, Igor E, Veith, Jean, Komar, Anton A, Gudkov, Andrei V, Gurova, Katerina V

“…Effective eradication of cancer requires treatment directed against multiple targets. The p53 and nuclear factor κB (NF-κB) pathways are dysregulated in nearly…”
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Small Molecules That Reactivate p53 in Renal Cell Carcinoma Reveal a NF-κB-Dependent Mechanism of p53 Suppression in Tumors by Katerina V. Gurova, Hill, Jason E., Canhui Guo, Anatoly Prokvolit, Burdelya, Lyudmila G., Eugenia Samoylova, Anna V. Khodyakova, Ram Ganapathi, Mahrukh Ganapathi, Natalia D. Tararova, Dmitry Bosykh, Dmitriy Lvovskiy, Thomas R. Webb, Stark, George R., Gudkov, Andrei V.

“…Renal cell carcinomas (RCC) commonly retain wild-type but functionally inactive p53, which is repressed by an unknown dominant mechanism. To help reveal this…”
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Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors by Gurova, Katerina V, Hill, Jason E, Guo, Canhui, Prokvolit, Anatoly, Burdelya, Lyudmila G, Samoylova, Eugenia, Khodyakova, Anna V, Ganapathi, Ram, Ganapathi, Mahrukh, Tararova, Natalia D, Bosykh, Dmitry, Lvovskiy, Dmitriy, Webb, Thomas R, Stark, George R, Gudkov, Andrei V

“…Renal cell carcinomas (RCC) commonly retain wild-type but functionally inactive p53, which is repressed by an unknown dominant mechanism. To help reveal this…”
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