Search Results - "Djuric, Niek"
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Adipokines as Immune Cell Modulators in Multiple Sclerosis
Published in International journal of molecular sciences (01-10-2021)“…Multiple sclerosis (MS), a chronic inflammatory and demyelinating disease of the central nervous system (CNS), is a major clinical and societal problem, which…”
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Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets
Published in Scientific reports (24-09-2021)“…Degeneration of the intervertebral disc is associated with a decrease in extra-cellular matrix (ECM) content due to an imbalance in anabolic and catabolic…”
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3
Influence of endplate avulsion and Modic changes on the inflammation profile of herniated discs: a proteomic and bioinformatic approach
Published in European spine journal (01-02-2022)“…Purpose The aim of this observational radiographic and proteomic study is to explore the influence of both Modic change (MC) and endplate avulsion (EPA) on the…”
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4
Study protocol: effect of infection, Modic and inflammation on clinical outcomes in surgery for radiculopathy (EIMICOR)
Published in BMC neurology (29-09-2021)“…Background Evidence indicates that inflammatory processes are involved in radicular pain as well as in resorption of herniated disc tissue. Furthermore there…”
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Correction to: Disc inflammation and Modic changes show an interaction effect on recovery after surgery for lumbar disc herniation
Published in European spine journal (01-03-2020)“…In Tables 3 and 4: In the first column and row, the text reads “Mixed model test (patients with Modic changes)”. This should have been just “Mixed model”. The…”
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Modic Changes in the Lumbar Spine: Exploring Their Association with Abdominal Aortic Calcification as a Potential Indicator of Systemic Atherosclerosis
Published in World neurosurgery (01-04-2024)“…This was a cross-sectional study on the correlation between abdominal aortic calcification (AAC) and Modic changes (MC). Little is known regarding the etiology…”
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Modic changes are associated with activation of intense inflammatory and host defense response pathways – molecular insights from proteomic analysis of human intervertebral discs
Published in The spine journal (01-01-2022)“…Patients with modic changes (MC) form a distinct clinical subset with reports of higher intensity of pain, poor clinical and surgical outcomes and higher…”
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Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets
Published in Scientific reports (24-09-2020)“…Intervertebral disc degeneration is accompanied by a loss of Extra-cellular matrix (ECM) due to an imbalance in anabolic and catabolic pathways. Identifying…”
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9
A systematic review evaluating the association of atherosclerosis and lumbar degenerative disc disease
Published in Brain & spine (01-01-2024)“…Lumbar disc herniation (LDH) and disc degeneration (DD) are associated with low back pain (LBP) and sciatica, which are common health problems. Emerging…”
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10
Modic changes are associated with activation of intense inflammatory and host defense response pathways -- molecular insights from proteomic analysis of human intervertebral discs
Published in The spine journal (01-09-2021)“…Patients with Modic changes form a distinct clinical subset with reports of higher intensity of pain, poor clinical and surgical outcomes and higher incidence…”
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Journal Article -
11
Disc inflammation and Modic changes show an interaction effect on recovery after surgery for lumbar disc herniation
Published in European spine journal (01-11-2019)“…Purpose To study the interaction between Modic changes (MC) and inflammation by macrophages in the disc, in relation to clinical symptoms before and after…”
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Gadolinium Enhancement Is Not Associated With Disc Inflammation in Patients With Sciatica
Published in Spine (Philadelphia, Pa. 1976) (15-06-2019)“…STUDY DESIGN.Retrospective observational histological study. OBJECTIVE.To evaluate the reliability of gadolinium enhancement as a marker for inflammation by…”
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