Search Results - "Djurendić Evgenija A."

New A-homo lactam D-homo lactone androstane derivative: Synthesis and evaluation of cytotoxic and anti-inflammatory activities in vitro by Savić, Marina P., Škorić, Dušan Đ., Kuzminac, Ivana Z., Jakimov, Dimitar S., Kojić, Vesna V., Rárová, Lucie, Strnad, Miroslav, Djurendić, Evgenija A.

“…[Display omitted] •New A-homo lactam D-homo lactone androstane derivative was synthesized.•Strong cytotoxic and anti-inflammatory activities were…”
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Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: Identification of a selective inhibitor of hormone-independent breast cancer cells by Nikolić, Andrea R., Petri, Edward T., Klisurić, Olivera R., Ćelić, Andjelka S., Jakimov, Dimitar S., Djurendić, Evgenija A., Penov Gaši, Katarina M., Sakač, Marija N.

“…[Display omitted] We report the synthesis of steroidal 16,17-seco-16,17a-dinitriles and investigate their antitumor cell properties. Compounds were evaluated…”
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Synthesis, structural analysis and antitumor activity of novel 17α-picolyl and 17(E)-picolinylidene A-modified androstane derivatives by Ajduković, Jovana J., Penov Gaši, Katarina M., Jakimov, Dimitar S., Klisurić, Olivera R., Jovanović-Šanta, Suzana S., Sakač, Marija N., Aleksić, Lidija D., Djurendić, Evgenija A.

“…[Display omitted] The heterocyclic ring at C-17 position of the androstane compounds plays an important role in biological activity. The aim of the present…”
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New oxygen-containing androstane derivatives: Synthesis and biological potential by Savić, Marina P, Kuzminac, Ivana Z, Škorić, Dušan Đ, Jakimov, Dimitar S, Rárová, Lucie, Sakač, Marija N, Djurendić, Evgenija A

“…New steroidal D-homo androstane derivatives with 5β,6β-epoxy-3,16-dicarbonyl, 6α- and 6β-hydroxy-3,16-dicarbonyl and 3β,5α-dihydroxy-6,16-dicarbonyl moieties…”
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Evaluation of A-ring fused pyridine d-modified androstane derivatives for antiproliferative and aldo-keto reductase 1C3 inhibitory activity by Savić, Marina P, Ajduković, Jovana J, Plavša, Jovana J, Bekić, Sofija S, Ćelić, Andjelka S, Klisurić, Olivera R, Jakimov, Dimitar S, Petri, Edward T, Djurendić, Evgenija A

“…New A-ring pyridine fused androstanes in 17a-homo-17-oxa (d-homo lactone), 17α-picolyl or 17( )-picolinylidene series were synthesized and validated by X-ray…”
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Comprehensive QSRR modeling as a starting point in characterization and further development of anticancer drugs based on 17α-picolyl and 17(E)-picolinylidene androstane structures by Kovačević, Strahinja Z., Podunavac-Kuzmanović, Sanja O., Jevrić, Lidija R., Jovanov, Pavle T., Djurendić, Evgenija A., Ajduković, Jovana J.

“…The selection of the most promising anticancer compounds from the pool of the huge number of synthesized molecules is a quite complex task. There are many…”
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Preselection of A- and B- modified d-homo lactone and d-seco androstane derivatives as potent compounds with antiproliferative activity against breast and prostate cancer cells – QSAR approach and molecular docking analysis by Kovačević, Strahinja Z., Podunavac-Kuzmanović, Sanja O., Jevrić, Lidija R., Vukić, Vladimir R., Savić, Marina P., Djurendić, Evgenija A.

“…The problem with trial-and-error approach in organic synthesis of targeted anticancer compounds can be successfully avoided by computational modeling of…”
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Non-linear assessment of anticancer activity of 17-picolyl and 17-picolinylidene androstane derivatives – Chemometric guidelines for further syntheses by Kovačević, Strahinja Z., Podunavac-Kuzmanović, Sanja O., Jevrić, Lidija R., Djurendić, Evgenija A., Ajduković, Jovana J.

“…[Display omitted] The present paper deals with prediction of cytotoxic activity of 17-picolyl and 17-picolinylidene androstane derivatives toward androgen…”
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Androstane derivatives induce apoptotic death in MDA-MB-231 breast cancer cells by Jakimov, Dimitar S., Kojić, Vesna V., Aleksić, Lidija D., Bogdanović, Gordana M., Ajduković, Jovana J., Djurendić, Evgenija A., Penov Gaši, Katarina M., Sakač, Marija N., Jovanović-Šanta, Suzana S.

“…[Display omitted] Biological investigation was conducted to study in vitro antiproliferative and pro-apoptotic potential of selected 17α-picolyl and…”
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17(E)-Picolinylidene androstane derivatives as potential inhibitors of prostate cancer cell growth: Antiproliferative activity and molecular docking studies by Ajduković, Jovana J., Djurendić, Evgenija A., Petri, Edward T., Klisurić, Olivera R., Ćelić, Andjelka S., Sakač, Marija N., Jakimov, Dimitar S., Gaši, Katarina M. Penov

“…We report a rapid and efficient synthesis of A-ring modified 17α-picolyl and 17(E)-picolinylidene androstane derivatives from dehydroepiandrosterone. Compounds…”
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Synthesis and cytotoxic activity of some 17-picolyl and 17-picolinylidene androstane derivatives by DJURENDIC, Evgenija A, AJDUKOVIC, Jovana J, SAKAC, Marija N, CSANADI, János J, KOJIC, Vesna V, BOGDANOVIC, Gordana M, PENOV GASI, Katarina M

“…New 17-picolyl and 17-picolinylidene androstane derivatives, 3–10, 15, 18, 19, 22 and 23, were synthesized starting from 17α-picolyl-androst-5-en-3β,17β-diol…”
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Microwave assisted synthesis and biomedical potency of salicyloyloxy and 2-methoxybenzoyloxy androstane and stigmastane derivatives by Penov Gaši, Katarina M., Djurendić, Evgenija A., Szécsi, Mihály, Gardi, János, Csanádi, János J., Klisurić, Olivera R., Dojčinović-Vujašković, Sanja V., Nikolić, Andrea R., Savić, Marina P., Ajduković, Jovana J., Oklješa, Aleksandar M., Kojić, Vesna V., Sakač, Marija N., Jovanović-Šanta, Suzana S.

“…[Display omitted] •New steroidal salicyloyl esters were synthesized by MW and conventional methods.•Antioxidant and cytotoxic activity of new compounds was…”
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Synthesis and antitumor activity of new d-seco and d-homo androstane derivatives by DJURENDIC, Evgenija A, ZAVIS, Marina P, SAKAC, Marija N, CANADI, Janos J, KOJIC, Vesna V, BOGDANOVIC, Gordana M, PENOV GASI, Katarina M

“…Starting from 3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile ( 1), the new 16,17-secoandrostane derivatives 4– 9 were synthesized. On the other hand,…”
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Synthesis and biological evaluation of some new A,B-ring modified steroidal d-lactones by DJURENDIC, Evgenija A, SAKAC, Marija N, ZAVIS, Marina P, GAKOVIC, Andrea R, CANADI, Janos J, ANDRIC, Siluana A, KLISURIC, Oliuera R, KOJIC, Vesna V, BOGDANOVIC, Gordana M, PENOV GASI, Katarina M

“…Starting from the d-homo lactones of androst-4-en-3-one 3 and 4, prepared from 1 and 2, the new 17a homolactones 5– 12, 14 and 15, were synthesized. The…”
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Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives by Gaši, Katarina M. Penov, Brenesel, Maja Dj. Djurendić, Djurendić, Evgenija A., Sakač, Marija N., Čanadi, Janoš J., Daljev, Jovana J., Armbruster, Thomas, Andrić, Silvana, Sladić, Dušan M., Božić, Tatjana T., Novaković, Irena T., Juranić, Zorica D.

“…Starting from dehydroepiandrosterone ( 1) 17-picolyl ( 2), 17-picolinylidene ( 7), 17-picolinylidene-16-one ( 10 and 11), and 17-picolyl-16-one ( 15)…”
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Synthesis, X-ray crystal structures and biological activity of 16-amino-17-substituted-D-homo steroid derivatives by Penov Gaši, Katarina M., Miljković, Dušan A., Medić Mijačević, Ljubica D., Djurendić, Evgenija A., Stojanović, Srdjan Z., Sakač, Marija N., Djurendić, Maja Dj, Stanković, Slobodanka M., Lazar, Dušan, Andrić, Silvana, Kovačević, Radmila

“…D-Homo derivatives in the androstane and estrane series, 12– 19, were synthesized by a fragmentation-cyclization reaction of…”
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How to rank and discriminate artificial neural networks? Case study: prediction of anticancer activity of 17-picolyl and 17-picolinylidene androstane derivatives by Kovačević, Strahinja Z., Podunavac-Kuzmanović, Sanja O., Jevrić, Lidija R., Djurendić, Evgenija A., Ajduković, Jovana J., Gadžurić, Slobodan B., Vraneš, Milan B.

“…Model discrimination is still not a resolved task. The classical statistical approaches lead to different results (for the same models) and at the same time a…”
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Synthesis and Biological Evaluation of Some A,D-Ring Modified 16,17-Secoandrostane Derivatives by Djurendic, Evgenija A, Zavis, Marina P, Sakac, Marija N, Kojic, Vesna V, Bogdanovic, Gordana M, Gasi, Katarina M Penov

“…Starting from 3β-hydroxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile ( 1 ), the new 16,17-secoandrostane derivatives 2 - 11 were synthesized. Protection of the…”
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Synthesis, Structural Analysis and Cytotoxic Activity of Novel A- and B-Modified d-Homo Lactone Androstane Derivative by Savić, Marina P., Klisurić, Olivera R., Penov Gaši, Katarina M., Jakimov, Dimitar S., Sakač, Marija N., Djurendić, Evgenija A.

“…The d -homo androstane lactone 3β-hydroxy-17-oxa- d -homoandrost-5-en-16-one ( I) was transformed through intermediate compounds 17-oxa- d…”
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Determination of 17α-hydroxylase-C17,20-lyase (P45017α) enzyme activities and their inhibition by selected steroidal picolyl and picolinylidene compounds by Szabó, Nikoletta, Ajduković, Jovana J, Djurendić, Evgenija A, Sakač, Marija N, Ignáth, Imre, Gardi, János, Mahmoud, Gábor, Klisurić, Olivera R, Jovanović-Šanta, Suzana, Penov Gaši, Katarina M, Szécsi, Mihály

“…17α-hydroxylase-C17,20-lyase (P45017α) is a key regulator enzyme of the steroid hormone biosynthesis in both the adrenals and the testes. Inhibition of this…”
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