Search Results - "Djukanovic, R"

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma by KIAN FAN CHUNG, WENZEL, Sally E, BOULET, Louis-Philippe, BRIGHTLING, Christopher, CHANEZ, Pascal, DAHLEN, Sven-Erik, DJUKANOVIC, Ratko, FREY, Urs, GAGA, Mina, GIBSON, Peter, HAMID, Qutayba, JAJOUR, Nizar N, BROZEK, Jan L, MAUAD, Thais, SORKNESS, Ronald L, TEAGUE, W. Gerald, BUSH, Andrew, CASTRO, Mario, STERK, Peter J, ADCOCK, Ian M, BATEMAN, Eric D, BEL, Elisabeth H, BLEECKER, Eugene R

“…Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American…”
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Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation by Östling, Jörgen, Ax, Elisabeth, Calvén, Jenny, Thörn, Kristofer, Israelsson, Elisabeth, Öberg, Lisa, Wilson, Susan J., Ward, Jonathan A., Chauhan, Anoop, Sousa, Ana R., De Meulder, Bertrand, Baribaud, Frédéric, Sterk, Peter J., Guo, Yike, Dahlen, Barbro, Chanez, Pascal, Shaw, Dominick E., Krug, Norbert, Hohlfeld, Jens M., Sandström, Thomas, James, Anna, Hinks, Timothy S.C., Howarth, Peter H., Vaarala, Outi, van Geest, Marleen, Olsson, Henric, Ahmed, H., Auffray, C., Bakke, P., Bansal, A.T., Bates, S., Bel, E.H., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brandsma, J., Bucchioni, E., Bush, A., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F.K., Corfield, J., D'Amico, A., De Meulder, B., Djukanovic, R., Fichtner, K., Fleming, L.J., Formaggio, E., Frey, U., Goss, V., Guo, Y., Hashimoto, S., Haughney, J., Hekking, P.W., Higenbottam, T., Hohlfeld, J.M., Holweg, C., Horváth, I., James, A.J., Knowles, R., Loza, M.J., Manta, A., Matthews, J.G., Mazein, A., Meiser, A., Middelveld, R.J.M., Miralpeix, M., Montuschi, P., Murray, C.S., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Postle, A., Powel, P., Praticò, G., Riley, J., Roberts, G., Rowe, A., Sandström, T., Schofield, J.P.R., Selby, A., Shaw, D.E., Sigmund, R., Singer, F., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Aalderen, W.M., van Geest, M., Vestbo, J., Vissing, N.H., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

“…Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) to asthma severity and decreased lung function, the role of IL-6…”
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Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma by Tariq, K., Schofield, J.P.R., Nicholas, B.L., Burg, D., Brandsma, J., Bansal, A.T., Wilson, S.J., Lutter, R., Fowler, S.J., Bakke, Caruso, M., Dahlen, B., Horváth, I., Krug, N., Montuschi, P., Sanak, M., Sandström, T., Geiser, T., Pandis, I., Sousa, A.R., Adcock, I.M., Shaw, D.E., Auffray, C., Howarth, P.H., Sterk, P.J., Chung, K.F., Skipp, P.J., Dimitrov, B., Djukanović, R.

“…Gastro-oesophageal reflux disease (GORD) has long been associated with poor asthma control without an established cause-effect relationship. 610 asthmatics…”
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Inflammatory cells in the airways in COPD by O’Donnell, R, Breen, D, Wilson, S, Djukanovic, R

“…Airway inflammation is central to the pathogenesis of both airway remodelling and parenchymal destruction in chronic obstructive pulmonary disease (COPD)…”
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Pathway discovery using transcriptomic profiles in adult-onset severe asthma by Hekking, Pieter-Paul, Loza, Matt J., Pavlidis, Stelios, de Meulder, Bertrand, Lefaudeux, Diane, Baribaud, Fred, Auffray, Charles, Brinkman, Paul, Lutter, Rene, Bansal, Aruna T., Sousa, Ana R., Bates, Steve A., Pandis, Yannis, Fleming, Louise J., Shaw, Dominique E., Fowler, Stephen J., Meiser, Andrea, Sun, Kai, Corfield, Julie, Howarth, Peter H., Bel, Elisabeth H., Adcock, Ian M., Chung, Kian Fan, Djukanovic, Ratko, Adcock, I.M., Auffray, C., Bakke, P., Bansal, A.T., Baribaud, F., Bates, S., Bel, E.H., Bigler, J., Bisgaard, H., Boedigheimer, M.J., Bønnelykke, K., Brandsma, J., Bucchioni, E., Burg, D., Caruso, M., Chanez, P., Chung, F.K., Compton, C.H., Corfield, J., D'Amico, A., Dahlen, S.E., De Meulder, B., Erpenbeck, V.J., Erzen, D., Fichtner, K., Fitch, N., Formaggio, E., Frey, U., Gahlemann, M., Geiser, T., Hashimoto, S., Haughney, J., Hedlin, G., Hohlfeld, J.M., Holweg, C., Horváth, I., Howarth, P., Knowles, R., Krug, N., Lefaudeux, D., Loza, M.J., Lutter, R., Manta, A., Matthews, J.G., Mazein, A., Middelveld, R.J.M., Mores, N., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Powel, P., Praticò, G., Valls, M Puig, Rao, N., Riley, J., Roberts, G., Rowe, A., Sandström, T., Seibold, W., Selby, A., Sigmund, R., Singer, F., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Geest, M., Vestbo, J., Vissing, N.H., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

“…Adult-onset severe asthma is characterized by highly symptomatic disease despite high-intensity asthma treatments. Understanding of the underlying pathways of…”
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Treatable traits in the European U‐BIOPRED adult asthma cohorts by Simpson, Andrew J., Hekking, Pieter‐Paul, Shaw, Dominick E., Fleming, Louise J., Roberts, Graham, Riley, John H., Bates, Stewart, Sousa, Ana R., Bansal, Aruna T., Pandis, Ioannis, Sun, Kai, Bakke, Per S., Caruso, Massimo, Dahlén, Barbro, Dahlén, Sven‐Erik, Horvath, Ildiko, Krug, Norbert, Montuschi, Paolo, Sandstrom, Thomas, Singer, Florian, Adcock, Ian M., Wagers, Scott S., Djukanovic, Ratko, Chung, Kian Fan, Sterk, Peter J., Fowler, Stephen J., Ahmed, H, Auffray, C, Baribaud, F, Bel, E. H, Bisgaard, H, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Chaiboonchoe, A, Chanez, P, Compton, C. H, Corfield, J, D'Amico, A, De Meulder, B, Erpenbeck, V. J, Erzen, D, Fichtner, K, Fleming, L. J, Formaggio, E, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P. W, Higenbottam, T, Hohlfeld, J. M, Holweg, C, Horváth, I, Howarth, P, James, A. J, Knowles, R, Knox, A. J, Lefaudeux, D, Lutter, R, Manta, A, Masefield, S, Matthews, J. G, Mazein, A, Meiser, A, Middelveld, R. J. M, Miralpeix, M, Mores, N, Murray, C. S, Myles, D, Pahus, L, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J. P. R, Selby, A, Sigmund, R, Skipp, P. J, Thornton, B, Aalderen, W. M, Geest, M, Vestbo, J, Vissing, N. H, Wagener, A. H, Weiszhart, Z, Wheelock, C. E, Wilson, S. J

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Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort by Alahmadi, Fahad H., Simpson, Andrew J., Gomez, Cristina, Ericsson, Magnus, Thörngren, John-Olof, Wheelock, Craig E., Shaw, Dominic E., Fleming, Louise J., Riley, John, Bates, Stewart, Sousa, Ana R., Bansal, Aruna T., Pandis, Ioannis, Sun, Kai, Caruso, Massimo, Chanez, Pascal, Dahlén, Barbro, Horvath, Ildiko, Krug, Norbert, Singer, Florian, Wagers, Scott, Adcock, Ian M., Djukanovic, Ratko, Dahlen, Sven-Erik, Fowler, Stephen J., Adcock, I.M., Ahmed, H., Auffray, C., Bakke, P., Bansal, A.T., Bates, S., Bel, E.H., Bisgaard, H., Boedigheimer, M.J., Bønnelykke, K., Brinkman, P., Bucchioni, E., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F.K., D'Amico, A., Dahlèn, B., Dahlén, S.E., Erpenbeck, V.J., Fichtner, K., Fitch, N., Fleming, L.J., Formaggio, E., Fowler, S.J., Gahlemann, M., Geiser, T., Goss, V., Guo, Y., Hedlin, G., Hekking, P.W., Higenbottam, T., Holweg, C., Horváth, I., Howarth, P., James, A.J., Knowles, R.G., Knox, A.J., Krug, N., Lefaudeux, D., Lutter, R., Manta, A., Matthews, J.G., Meiser, A., Middelveld, R.J.M., Mores, N., Murray, C.S., Musial, J., Myles, D., Pahus, L., Pavlidis, S., Postle, A., Powel, P., Praticò, G., Valls, M. Puig, Rao, N., Riley, J., Roberts, A., Rowe, A., Schofield, J.P.R., Seibold, W., Selby, A., Sigmund, R., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Aalderen, W.M., Vestbo, J., Vissing, N.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

“…Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor…”
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Methods of sputum processing for cell counts, immunocytochemistry and in situ hybridisation by Efthimiadis, A, Spanevello, A, Hamid, Q, Kelly, M M, Linden, M, Louis, R, Pizzichini, M M M, Pizzichini, E, Ronchi, C, Van Overvel, F, Djukanović, R

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Prosurvival activity for airway neutrophils in severe asthma by Uddin, Mohib, Nong, Guangmin, Ward, Jonathan, Seumois, Grégory, Prince, Lynne R, Wilson, Susan J, Cornelius, Victoria, Dent, Gordon, Djukanovic, Ratko

“…Airway neutrophilia is a recognised feature of chronic severe asthma, but the mechanisms that underlie this phenomenon are unknown. Evidence for factors…”
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Asthma Sub-Phenotyping in Plasma from U-BIOPRED and BIOAIR Using Array-Based Proteomics by Mikus, Maria, Kolmert, J., Andersson, L. I., James, A., Gomez, C., Dahlen, B. U., De Meulder, B., Djukanovic, R., Sterk, P. J., Adcock, I. M., Nilsson, Peter, Dahlen, S. K.

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The relationship between airways inflammation and asthma severity by LOUIS, R, LAU, L. C. K, BRON, A. O, ROLDAAN, A. C, RADERMECKER, M, DJUKANOVIC, R

“…In order to investigate the relationship between airways inflammation and disease severity, and improve the understanding of persistent asthma, 74 asthmatics,…”
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The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma by Abraham, B, Antó, JM, Barreiro, E, Bel, EHD, Bonsignore, G, Bousquet, J, Castellsague, J, Chanez, P, Cibella, F, Cuttitta, G

“…Since severe asthma is a poorly understood, major health problem, 12 clinical specialist centres in nine European countries formed a European Network For…”
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Is the neutrophil a worthy target in severe asthma and chronic obstructive pulmonary disease? by Louis, R., Djukanovic, R.

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EUFOREA summit in Brussels 2023: inspiring the future of allergy & respiratory care by Hellings, P W, Lau, S, Scadding, G K, Bjermer, L, Backer, V, Chaker, A M, Conti, D M, De Corso, E, Diamant, Z, Djukanovic, R, Fokkens, W, Gevaert, P, Gray, C L, Han, J K, Heaney, L G, Hoffmann, H J, Jesenak, M, Johansen, P, Kumaran, M S, McDonald, M, Melén, E, Mullol, J, Reitsma, S, Ryan, D, Scadding, G, Schmid-Grendelmeier, P, Teeling, T, Odemyr, M, Wahn, U

“…In March 2023, the European Forum for Research and Education in Allergy and Airways diseases (EUFOREA) organized its bi-annual Summit in Brussels with expert…”
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Building the investment case for asthma R&D: the European Asthma Research and Innovation Partnership argument by Walker, S. M., Akdis, C., Dahlen, S. E., Djukanovic, R., Edwards, J., Garcia-Marcos, L., Johnston, S., Kupczyk, M., Martin, T., Myles, D., Palkonen, S., Papadopoulos, N., Powell, P., Riley, J.

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The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma by Hamilton, L. M., Torres-Lozano, C., Puddicombe, S. M., Richter, A., Kimber, I., Dearman, R. J., Vrugt, B., Aalbers, R., Holgate, S. T., Djukanović, R., Wilson, S. J., Davies, D. E.

“…Summary Background The extent of epithelial injury in asthma is reflected by expression of the epidermal growth factor receptor (EGFR), which is increased in…”
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Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD by O’Donnell, R A, Peebles, C, Ward, J A, Daraker, A, Angco, G, Broberg, P, Pierrou, S, Lund, J, Holgate, S T, Davies, D E, Delany, D J, Wilson, S J, Djukanovic, R

“…Background: Considerable research has been conducted into the nature of airway inflammation in chronic obstructive pulmonary disease (COPD) but the…”
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Safety of long-acting beta-agonists: urgent need to clear the air remains by Beasley, R, Martinez, F D, Hackshaw, A, Rabe, K F, Sterk, P J, Djukanovic, R

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Microbial products in allergy prevention and therapy by Matricardi, P. M., Bjorksten, B., Bonini, S., Bousquet, J., Djukanovic, R., Dreborg, S., Gereda, J., Malling, H.‐J., Popov, T., Raz, E., Renz, H.

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Longitudinal Replication Of Severe Asthma Exhaled Breath Phenotypes By The U-Biopred Electronic Nose Platform by Brinkman, P., Wagener, A. H., Hekking, P. -P, Bansal, A. T., Wang, Y., Weda, H., Knobel, H. H., Vink, T. J., Rattray, N. J., D'Amico, A., Pennazza, G., Santonico, M., Bakke, P. S., Caruso, M., Chung, K. F., Corfield, J., Dahlen, S. -E, Djukanovic, R., Geiser, T., Horvath, I., Krug, N., Musial, J., Shaw, D. E., Pandis, I., Sandström, T., Sousa, A. R., Montuschi, P., Fowler, S. J., Sterk, P. J.

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