Search Results - "Djafarzadeh, Siamak"

Mitochondrial function of immune cells in septic shock: A prospective observational cohort study by Merz, Tobias M, Pereira, Adriano J, Schürch, Roger, Schefold, Joerg C, Jakob, Stephan M, Takala, Jukka, Djafarzadeh, Siamak

“…Reduced cellular ATP synthesis due to impaired mitochondrial function of immune cells may be a factor influencing the immune response in septic shock. We…”
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Mitochondrial function in sepsis by Jeger, Victor, Djafarzadeh, Siamak, Jakob, Stephan M., Takala, Jukka

“…Background The relevance of mitochondrial dysfunction as to pathogenesis of multiple organ dysfunction and failure in sepsis is controversial. This focused…”
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Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis by Corrêa, Thiago Domingos, Pereira, Adriano José, Brandt, Sebastian, Vuda, Madhusudanarao, Djafarzadeh, Siamak, Takala, Jukka, Jakob, Stephan Mathias

“…A decrease in blood lactate levels (Lac) >10% during the first hours of resuscitation in sepsis is associated with better outcomes, but the mechanisms are…”
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Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes by Djafarzadeh, Siamak, Vuda, Madhusudanarao, Takala, Jukka, Jakob, Stephan M

“…During sepsis, liver dysfunction is common, and failure of mitochondria to effectively couple oxygen consumption with energy production has been described. In…”
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Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro by Takala, Jukka, Jakob, Stephan M., Porta, Francesca, Brandt, Sebastian, Jeger, Victor, Djafarzadeh, Siamak

“…Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes…”
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Correction: Effect of Remifentanil on Mitochondrial Oxygen Consumption of Cultured Human Hepatocytes by Djafarzadeh, Siamak, Vuda, Madhusudanarao, Takala, Jukka, Jakob, Stephan M.

“…The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Citation: Djafarzadeh S, Vuda M,…”
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Crystal Structure of Yeast Ypr118w, a Methylthioribose-1-phosphate Isomerase Related to Regulatory eIF2B Subunits by Bumann, Mario, Djafarzadeh, Siamak, Oberholzer, Anselm Erich, Bigler, Peter, Altmann, Michael, Trachsel, Hans, Baumann, Ulrich

“…Ypr118w is a non-essential, low copy number gene product from Saccharomyces cerevisiae . It belongs to the PFAM family PF01008, which contains the α-, β-,…”
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Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements by Djafarzadeh, Siamak, Jakob, Stephan Mathias

“…Mitochondria are involved in cellular energy metabolism and use oxygen to produce energy in the form of adenosine triphosphate (ATP). Differential…”
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Signaling Pathways Involved in Dephosphorylation and Localization of the Actin-Binding Protein Cofilin in Stimulated Human Neutrophils by Djafarzadeh, Siamak, Niggli, Verena

“…We have studied activation-induced dephosphorylation of proteins in human neutrophils loaded with [32P]orthophosphate using two-dimensional gel electrophoresis…”
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High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells by Djafarzadeh, Siamak, Jakob, Stephan M

“…A high-resolution oxygraph is a device for measuring cellular oxygen consumption in a closed-chamber system with very high resolution and sensitivity in…”
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Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements by Djafarzadeh, Siamak, Jakob, Stephan Mathias

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High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells by Djafarzadeh, Siamak, Jakob, Stephan M.

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Angiotensin II in Septic Shock: Effects on Tissue Perfusion, Organ Function, and Mitochondrial Respiration in a Porcine Model of Fecal Peritonitis by Corrêa, Thiago D, Jeger, Victor, Pereira, Adriano José, Takala, Jukka, Djafarzadeh, Siamak, Jakob, Stephan M

“…OBJECTIVES:To compare effects of norepinephrine and angiotensin II in experimental sepsis on hemodynamics, organ function, and mitochondrial respiration…”
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Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions by Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G, von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M, Rieben, Robert, Lepper, Philipp M

“…Dendritic cells (DC) are professional antigen presenting cells that represent an important link between innate and adaptive immunity. Danger signals such as…”
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The Effects of Fentanyl on Hepatic Mitochondrial Function by Djafarzadeh, Siamak, Vuda, Madhusudanarao, Jeger, Victor, Takala, Jukka, Jakob, Stephan M.

“…BACKGROUND:Remifentanil interferes with hepatic mitochondrial function. The aim of the present study was to evaluate whether hepatic mitochondrial function is…”
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The Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow by Moller, Per W, Hana, Anisa, Heinisch, Paul Philipp, Liu, Shengchen, Djafarzadeh, Siamak, Haenggi, Matthias, Bloch, Andreas, Takala, Jukka, Jakob, Stephan M, Berger, David

“…BACKGROUND:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is gaining widespread use in the treatment of severe cardiorespiratory failure. Blood…”
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Mitochondrial integrity during early reperfusion in an isolated rat heart model of donation after circulatory death—consequences of ischemic duration by Wyss, Rahel K., Méndez-Carmona, Natalia, Sanz, Maria-Nieves, Arnold, Maria, Segiser, Adrian, Fiedler, Georg M., Carrel, Thierry P., Djafarzadeh, Siamak, Tevaearai Stahel, Hendrik T., Longnus, Sarah L.

“…Cardioprotection and graft evaluation after ischemia-reperfusion (IR) are essential in facilitating heart transplantation with donation after circulatory…”
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Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function by Corrêa, Thiago Domingos, Vuda, Madhusudanarao, Takala, Jukka, Djafarzadeh, Siamak, Silva, Eliézer, Jakob, Stephan Mathias

“…The objective of this study was to evaluate the effects of two different mean arterial blood pressure (MAP) targets on needs for resuscitation, organ…”
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Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions by Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G., von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M., Rieben, Robert, Lepper, Philipp M.

“…Dendritic cells (DC) are professional antigen presenting cells that represent an important link between innate and adaptive immunity. Danger signals such as…”
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Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis by Corrêa, Thiago D, Vuda, Madhusudanarao, Blaser, Annika Reintam, Takala, Jukka, Djafarzadeh, Siamak, Dünser, Martin W, Silva, Eliézer, Lensch, Michael, Wilkens, Ludwig, Jakob, Stephan M

“…OBJECTIVE:Early treatment in sepsis may improve outcome. The aim of this study was to evaluate how the delay in starting resuscitation influences the severity…”
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