Search Results - "Dixon, Michael J."

Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial by Kunkler, Ian H, Prof, Williams, Linda J, PhD, Jack, Wilma J L, MBChB, Cameron, David A, Prof, Dixon, J Michael, Prof

“…Summary Background For most older women with early breast cancer, standard treatment after breast-conserving surgery is adjuvant whole-breast radiotherapy and…”
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Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets by Cassetta, Luca, Fragkogianni, Stamatina, Sims, Andrew H., Swierczak, Agnieszka, Forrester, Lesley M., Zhang, Hui, Soong, Daniel Y.H., Cotechini, Tiziana, Anur, Pavana, Lin, Elaine Y., Fidanza, Antonella, Lopez-Yrigoyen, Martha, Millar, Michael R., Urman, Alexandra, Ai, Zhichao, Spellman, Paul T., Hwang, E. Shelley, Dixon, J. Michael, Wiechmann, Lisa, Coussens, Lisa M., Smith, Harriet O., Pollard, Jeffrey W.

“…The roles of tumor-associated macrophages (TAMs) and circulating monocytes in human cancer are poorly understood. Here, we show that monocyte subpopulation…”
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Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers by Selli, Cigdem, Dixon, J Michael, Sims, Andrew H

“…Approximately 70% of patients have breast cancers that are oestrogen receptor alpha positive (ER+) and are therefore candidates for endocrine treatment. Many…”
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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes by Nestor, Colm E, Ottaviano, Raffaele, Reddington, James, Sproul, Duncan, Reinhardt, Diana, Dunican, Donncha, Katz, Elad, Dixon, J Michael, Harrison, David J, Meehan, Richard R

“…The discovery of substantial amounts of 5-hydroxymethylcytosine (5hmC), formed by the oxidation of 5-methylcytosine (5mC), in various mouse tissues and human…”
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Accurate Prediction and Validation of Response to Endocrine Therapy in Breast Cancer by Turnbull, Arran K, Arthur, Laura M, Renshaw, Lorna, Larionov, Alexey A, Kay, Charlene, Dunbier, Anita K, Thomas, Jeremy S, Dowsett, Mitch, Sims, Andrew H, Dixon, J Michael

“…Aromatase inhibitors (AIs) have an established role in the treatment of breast cancer. Response rates are only 50% to 70% in the neoadjuvant setting and lower…”
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Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group by Provenzano, Elena, Bossuyt, Veerle, Viale, Giuseppe, Cameron, David, Badve, Sunil, Denkert, Carsten, MacGrogan, Gaëtan, Penault-Llorca, Frédérique, Boughey, Judy, Curigliano, Giuseppe, Dixon, J Michael, Esserman, Laura, Fastner, Gerd, Kuehn, Thorsten, Peintinger, Florentia, von Minckwitz, Gunter, White, Julia, Yang, Wei, Symmans, W Fraser

“…Neoadjuvant systemic therapy is being used increasingly in the treatment of early-stage breast cancer. Response, in the form of pathological complete response,…”
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Accuracy and Surgical Impact of Magnetic Resonance Imaging in Breast Cancer Staging: Systematic Review and Meta-Analysis in Detection of Multifocal and Multicentric Cancer by HOUSSAMI, Nehmat, CIATTO, Stefano, MACASKILL, Petra, LORD, Sarah J, WARREN, Ruth M, DIXON, J. Michael, IRWIG, Les

“…PURPOSE We review the evidence on magnetic resonance imaging (MRI) in staging the affected breast to determine its accuracy and impact on treatment. METHODS…”
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A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis by Ferretti, Elisabetta, Li, Bingsi, Zewdu, Rediet, Wells, Victoria, Hebert, Jean M., Karner, Courtney, Anderson, Matthew J., Williams, Trevor, Dixon, Jill, Dixon, Michael J., Depew, Michael J., Selleri, Licia

“…Morphogenesis of mammalian facial processes requires coordination of cellular proliferation, migration, and apoptosis to develop intricate features. Cleft lip…”
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Breast implants and anaplastic large cell lymphoma by Dixon, J Michael, Clemens, Mark

“…An emerging safety concern for textured implants…”
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Outcomes of patients with inflammatory breast cancer treated by breast-conserving surgery by Brzezinska, Monika, Williams, Linda J., Thomas, Jeremy, Michael Dixon, J.

“…Purpose Inflammatory breast cancer (IBC) is rare and associated with a poor prognosis. Following neoadjuvant chemotherapy or endocrine therapy, the…”
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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features by Creighton, Chad J, Li, Xiaoxian, Landis, Melissa, Dixon, J. Michael, Neumeister, Veronique M, Sjolund, Ashley, Rimm, David L, Wong, Helen, Rodriguez, Angel, Herschkowitz, Jason I, Fan, Cheng, Zhang, Xiaomei, He, Xiaping, Pavlick, Anne, Gutierrez, M. Carolina, Renshaw, Lorna, Larionov, Alexey A, Faratian, Dana, Hilsenbeck, Susan G, Perou, Charles M, Lewis, Michael T, Rosen, Jeffrey M, Chang, Jenny C

“…Some breast cancers have been shown to contain a small fraction of cells characterized by CD44⁺/CD24⁻/low cell-surface antigen profile that have high…”
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Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor–Positive Breast Cancer by BASELGA, José, SEMIGLAZOV, Vladimir, STEINSEIFER, Jutta, MOLLOY, Betty, TOKAJI, Erika, GARDNER, Humphrey, PHILLIPS, Penny, STUMM, Michael, LANE, Heidi A, DIXON, J. Michael, JONAT, Walter, RUGO, Hope S, VAN DAM, Peter, MANIKHAS, Alexey, BELLET, Meritxell, MAYORDOMO, José, CAMPONE, Mario, KUBISTA, Ernst, GREIL, Richard, BIANCHI, Giulia

“…Cross-talk between the estrogen receptor (ER) and the phosphoinositide-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathways is a mechanism of…”
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Factors affecting the number of sentinel lymph nodes removed in patients having surgery for breast cancer by Dixon, J. Michael, Grewar, Julia, Twelves, Dominique, Graham, Ashley, Martinez-Perez, Carlos, Turnbull, Arran

“…Purpose The goal of sentinel lymph node biopsy is to establish the presence or absence of cancer cells in regional axillary nodes. The number of sentinel nodes…”
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Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only by Ludwig, Kerstin U, Böhmer, Anne C, Bowes, John, Nikolic, Miloš, Ishorst, Nina, Wyatt, Niki, Hammond, Nigel L, Gölz, Lina, Thieme, Frederic, Barth, Sandra, Schuenke, Hannah, Klamt, Johanna, Spielmann, Malte, Aldhorae, Khalid, Rojas-Martinez, Augusto, Nöthen, Markus M, Rada-Iglesias, Alvaro, Dixon, Michael J, Knapp, Michael, Mangold, Elisabeth

“…Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common human birth defects with multifactorial etiology. Here, we present…”
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Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development by Falcon, Karla T, Watt, Kristin E N, Dash, Soma, Zhao, Ruonan, Sakai, Daisuke, Moore, Emma L, Fitriasari, Sharien, Childers, Melissa, Sardiu, Mihaela E, Swanson, Selene, Tsuchiya, Dai, Unruh, Jay, Bugarinovic, George, Li, Lin, Shiang, Rita, Achilleos, Annita, Dixon, Jill, Dixon, Michael J, Trainor, Paul A

“…Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is a critical rate-limiting step in ribosome biogenesis, which is essential for cell survival…”
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Suppression of Plasma Estrogen Levels by Letrozole and Anastrozole Is Related to Body Mass Index in Patients With Breast Cancer by Folkerd, Elizabeth J, Dixon, J Michael, Renshaw, Lorna, A'Hern, Roger P, Dowsett, Mitch

“…To investigate whether suppression of plasma estradiol and estrone sulfate levels by the aromatase inhibitors (AIs) anastrozole and letrozole is related to…”
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Magnetic Resonance Imaging Screening of the Contralateral Breast in Women With Newly Diagnosed Breast Cancer: Systematic Review and Meta-Analysis of Incremental Cancer Detection and Impact on Surgical Management by BRENNAN, Meagan Elizabeth, HOUSSAMI, Nehmat, LORD, Sarah, MACASKILL, Petra, IRWIG, Les, DIXON, J. Michael, WARREN, Ruth M. L, CIATTO, Stefano

“…Preoperative magnetic resonance imaging (MRI) is increasingly used for staging women with breast cancer, including screening for occult contralateral cancer…”
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Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer by Inda, Márcia A, Blok, Erik J, Kuppen, Peter J K, Charehbili, Ayoub, den Biezen-Timmermans, Eveline C, van Brussel, Anne, Fruytier, Sevgi E, Meershoek-Klein Kranenbarg, Elma, Kloet, Susan, van der Burg, Bart, Martens, John W M, Sims, Andrew H, Turnbull, Arran K, Dixon, J Michael, Verhaegh, Wim, Kroep, Judith R, van de Velde, Cornelis J H, van de Stolpe, Anja

“…Endocrine therapy is important for management of patients with estrogen receptor (ER)-positive breast cancer; however, positive ER staining does not reliably…”
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Mondor's disease of the breast: A cutaneous thromboembolic manifestation of Covid-19? by Renshaw, Lorna, Dixon, J Michael, Anderson, Julia, Turnbull, Arran K.

“…Mondor's disease is a rare disorder characterised by thrombosis of superficial veins within the subcutaneous tissue of the breast and other organs. While…”
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Prognostic Value of Ki67 Expression After Short-Term Presurgical Endocrine Therapy for Primary Breast Cancer by Dowsett, Mitch, Smith, Ian E., Ebbs, Stephen R., Dixon, J. Michael, Skene, Anthony, A'Hern, Roger, Salter, Janine, Detre, Simone, Hills, Margaret, Walsh, Geraldine

“…Tumor expression of the proliferation antigen Ki67 is widely used to assess the prognosis of cancer patients. A change in the expression of Ki67 after…”
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