Search Results - "Dixon, Darlene"

Genistein: Dual Role in Women’s Health by Yu, Linda, Rios, Eddy, Castro, Lysandra, Liu, Jingli, Yan, Yitang, Dixon, Darlene

“…Advanced research in recent years has revealed the important role of nutrients in the protection of women’s health and in the prevention of women’s diseases…”
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ERα36, a variant of estrogen receptor α, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells by Yan, Yitang, Yu, Linda, Castro, Lysandra, Dixon, Darlene

“…ERα36 is a naturally occurring, membrane-associated, isoform of estrogen receptor α. The expression of ERα36 is due to alternative splicing and different…”
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Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System by Dixon, Darlene, Alison, Roger, Bach, Ute, Colman, Karyn, Foley, George L., Harleman, Johannes H., Haworth, Richard, Herbert, Ronald, Heuser, Anke, Long, Gerald, Mirsky, Michael, Regan, Karen, esch, Eric Van, Westwood, F. Russell, Vidal, Justin, Yoshida, Midori

“…The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint…”
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Recommendations from the INHAND Apoptosis/Necrosis Working Group by Elmore, Susan A., Dixon, Darlene, Hailey, James R., Harada, Takanori, Herbert, Ronald A., Maronpot, Robert R., Nolte, Thomas, Rehg, Jerold E., Rittinghausen, Susanne, Rosol, Thomas J., Satoh, Hiroshi, Vidal, Justin D., Willard-Mack, Cynthia L., Creasy, Dianne M.

“…Historically, there has been confusion relating to the diagnostic nomenclature for individual cell death. Toxicologic pathologists have generally used the…”
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Tobacco Smoke Condensate Induces Morphologic Changes in Human Papillomavirus-Positive Cervical Epithelial Cells Consistent with Epithelial to Mesenchymal Transition (EMT) with Activation of Receptor Tyrosine Kinases and Regulation of TGFB by Mark, Zaniya A, Yu, Linda, Castro, Lysandra, Gao, Xiaohua, Rodriguez, Noelle R, Sutton, Deloris, Scappini, Erica, Tucker, Charles J, Wine, Rob, Yan, Yitang, Motley, Evangeline, Dixon, Darlene

“…High-risk human papillomavirus (HR-HPV; HPV-16) and cigarette smoking are associated with cervical cancer (CC); however, the underlying mechanism(s) remain…”
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Lung tumors in mice induced by “whole-life” inorganic arsenic exposure at human-relevant doses by Waalkes, Michael P., Qu, Wei, Tokar, Erik J., Kissling, Grace E., Dixon, Darlene

“…In mice, inorganic arsenic in the drinking water in the parts per million range via the dam during in utero life or with whole-life exposure is a multi-site…”
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Arsenic and Diabetes Mellitus: A Putative Role for the Immune System by Liu, Jingli, Hermon, Tonia, Gao, Xiaohua, Dixon, Darlene, Xiao, Hang

“…Diabetes mellitus (DM) is an enormous public health issue worldwide. Recent data suggest that chronic arsenic exposure is linked to the risk of developing type…”
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Editorial: Environmental impacts on women’s health disparities and reproductive health: advancing environmental health equity in clinical and public health practice by Smarr, Melissa M., Rappazzo, Kristen M., Dixon, Darlene

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Racism as a public health issue in environmental health disparities and environmental justice: working toward solutions by Beard, Sharon, Freeman, Kenda, Velasco, Maria L, Boyd, Windy, Chamberlain, Toccara, Latoni, Alfonso, Lasko, Denise, Lunn, Ruth M, O'Fallon, Liam, Packenham, Joan, Smarr, Melissa M, Arnette, Robin, Cavalier-Keck, Crystal, Keck, Jason, Muhammad, Naeema, Wilson, Omega, Wilson, Brenda, Wilson, Ayo, Dixon, Darlene

“…Environmental health research in the US has shown that racial and ethnic minorities and members of low-socioeconomic groups, are disproportionately burdened by…”
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Prolonged Cadmium Exposure Alters Migration Dynamics and Increases Heterogeneity of Human Uterine Fibroid Cells-Insights from Time Lapse Analysis by Yan, Yitang, Shi, Min, Fannin, Rick, Yu, Linda, Liu, Jingli, Castro, Lysandra, Dixon, Darlene

“…Cadmium (Cd) is one of the most prevalent environmental heavy metal contaminants and is considered an endocrine disruptor and carcinogen. In women with uterine…”
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Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium by Daniely, Yaron, Liao, Grace, Dixon, Darlene, Linnoila, R Ilona, Lori, Adriana, Randell, Scott H, Oren, Moshe, Jetten, Anton M

“…The trachea and esophagus originate from the foregut endoderm during early embryonic development. Their epithelia undergo a series of changes involving the…”
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Immunoexpression of Steroid Hormone Receptors and Proliferation Markers in Uterine Leiomyoma and Normal Myometrial Tissues from the Miniature Pig, Sus scrofa by Mozzachio, Kristie, Moore, Alicia B., Kissling, Grace E., Dixon, Darlene

“…Uterine leiomyomas in miniature pet pigs occur similarly to those in women with regard to frequency, age, parity, and cycling. Clinical signs, gross, and…”
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Effects of Liver X Receptor Agonist Treatment on Pulmonary Inflammation and Host Defense by Smoak, Kathleen, Madenspacher, Jennifer, Jeyaseelan, Samithamby, Williams, Belinda, Dixon, Darlene, Poch, Katie R, Nick, Jerry A, Worthen, G. Scott, Fessler, Michael B

“…Liver X receptor (LXR) alpha and beta are members of the nuclear receptor superfamily of ligand-activated transcription factors. Best known for triggering…”
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ATP-binding Cassette Transporter G1 Deficiency Dysregulates Host Defense in the Lung by DRAPER, David W, MADENSPACHER, Jennifer H, DIXON, Darlene, KING, Debra H, REMALEY, Alan T, FESSLER, Michael B

“…Mice with genetic deletion of the cholesterol efflux transporter, ATP-binding cassette (ABC) G1, have pulmonary lipidosis and chronic pulmonary inflammation…”
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A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells by Di, Xudong, Andrews, Danica MK, Tucker, Charles J, Yu, Linda, Moore, Alicia B, Zheng, Xiaolin, Castro, Lysandra, Hermon, Tonia, Xiao, Hang, Dixon, Darlene

“…Previously, we found that high doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. In this study, using microarray…”
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The Life Cycle of the Uterine Fibroid Myocyte by Flake, Gordon P., Moore, Alicia B., Sutton, Deloris, Flagler, Norris, Clayton, Natasha, Kissling, Grace E., Hall, Benita Wicker, Horton, John, Walmer, David, Robboy, Stanley J., Dixon, Darlene

“…Purpose of Review Uterine fibroids are common benign tumors of women in the USA and worldwide, yet the biological nature and pathogenesis of these tumors…”
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Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture by Moore, Alicia B, Yu, Linda, Swartz, Carol D, Zheng, Xaiolin, Wang, Lu, Castro, Lysandra, Kissling, Grace E, Walmer, David K, Robboy, Stanley J, Dixon, Darlene

“…Uterine leiomyomas (fibroids) are benign smooth muscle tumors that often contain an excessive extracellular matrix (ECM). In the present study, we investigated…”
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Estrogen receptor alpha (ERα) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium by Hermon, Tonia L., Moore, Alicia B., Yu, Linda, Kissling, Grace E., Castora, Frank J., Dixon, Darlene

“…It is thought that the growth of uterine leiomyomas may be mediated by the interaction of estrogen receptor alpha (ERα) and growth factor pathways and that…”
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Immortalization of Human Uterine Leiomyoma and Myometrial Cell Lines After Induction of Telomerase Activity: Molecular and Phenotypic Characteristics by Carney, Sara A, Tahara, Hidetoshi, Swartz, Carol D, Risinger, John I, He, Hong, Moore, Alicia B, Haseman, Joseph K, Barrett, J Carl, Dixon, Darlene

“…In vitro model systems for studying uterine leiomyomas are limited in that human-derived leiomyoma cells grow poorly in culture compared with normal myometrial…”
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The second National Institutes of Health International Congress on advances in uterine leiomyoma research: conference summary and future recommendations by Dixon, Darlene, Parrott, Estella C, Segars, James H, Olden, Kenneth, Pinn, Vivian W

“…To summarize the proceedings of the Advances in Uterine Leiomyoma Research: 2nd NIH International Congress, which was convened on February 24-25, 2005 by the…”
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