Search Results - "Dixit, VM"

Abstract BS1-1: Transcription factor stability and stem cell maintenance by Dixit, VM

“…Abstract Proto-oncogenes ETV1, ETV4, and ETV5 belong to the PEA3 family of ETS transcription factors and have been identified recently in prostate cancer…”
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Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4 by Kayagaki, Nobuhiko, Wong, Michael T., Stowe, Irma B., Ramani, Sree Ranjani, Gonzalez, Lino C., Akashi-Takamura, Sachiko, Miyake, Kensuke, Zhang, Juan, Lee, Wyne P., Muszyński, Artur, Forsberg, Lennart S., Carlson, Russell W., Dixit, Vishva M.

“…Gram-negative bacteria including Escherichia coli, Citrobacter rodentium, Salmonella typhimurium, and Shigella flexneri are sensed in an ill-defined manner by…”
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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 by Galluzzi, L, Bravo-San Pedro, J M, Vitale, I, Aaronson, S A, Abrams, J M, Adam, D, Alnemri, E S, Andrews, D, Baehrecke, E H, Bazan, N G, Bertrand, M J, Blagosklonny, M V, Blomgren, K, Borner, C, Bredesen, D E, Brenner, C, Campanella, M, Candi, E, Cecconi, F, Chan, F K, Chandel, N S, Cheng, E H, Chipuk, J E, Cidlowski, J A, Ciechanover, A, Dawson, V L, De Laurenzi, V, De Maria, R, Debatin, K-M, Di Daniele, N, Dixit, V M, Dynlacht, B D, El-Deiry, W S, Fimia, G M, Flavell, R A, Garrido, C, Green, D R, Gronemeyer, H, Hajnoczky, G, Hardwick, J M, Hengartner, M O, Ichijo, H, Joseph, B, Jost, P J, Kaufmann, T, Kepp, O, Klionsky, D J, Knight, R A, Kumar, S, Lemasters, J J, Levine, B, Linkermann, A, Lipton, S A, Lockshin, R A, López-Otín, C, Lugli, E, Madeo, F, Malorni, W, Marine, J-C, Martin, S J, Martinou, J-C, Medema, J P, Meier, P, Melino, S, Mizushima, N, Moll, U, Muñoz-Pinedo, C, Nuñez, G, Oberst, A, Panaretakis, T, Penninger, J M, Peter, M E, Piacentini, M, Pinton, P, Prehn, J H, Puthalakath, H, Rabinovich, G A, Ravichandran, K S, Rizzuto, R, Rodrigues, C M, Rubinsztein, D C, Rudel, T, Stockwell, B R, Szabadkai, G, Tait, S W, Tang, H L, Tavernarakis, N, Tsujimoto, Y, Vanden Berghe, T, Vandenabeele, P, Villunger, A, Wagner, E F, Walczak, H, White, E, Wood, W G, Yuan, J, Zakeri, Z, Zhivotovsky, B, Melino, G, Kroemer, G

“…Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an…”
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Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases by Minina, Elena A., Staal, Jens, Alvarez, Vanina E., Berges, John A., Berman-Frank, Ilana, Beyaert, Rudi, Bidle, Kay D., Bornancin, Frédéric, Casanova, Magali, Cazzulo, Juan J., Choi, Chang Jae, Coll, Nuria S., Dixit, Vishva M., Dolinar, Marko, Fasel, Nicolas, Funk, Christiane, Gallois, Patrick, Gevaert, Kris, Gutierrez-Beltran, Emilio, Hailfinger, Stephan, Klemenčič, Marina, Koonin, Eugene V., Krappmann, Daniel, Linusson, Anna, Machado, Maurício F.M., Madeo, Frank, Megeney, Lynn A., Moschou, Panagiotis N., Mottram, Jeremy C., Nyström, Thomas, Osiewacz, Heinz D., Overall, Christopher M., Pandey, Kailash C., Ruland, Jürgen, Salvesen, Guy S., Shi, Yigong, Smertenko, Andrei, Stael, Simon, Ståhlberg, Jerry, Suárez, María Fernanda, Thome, Margot, Tuominen, Hannele, Van Breusegem, Frank, van der Hoorn, Renier A.L., Vardi, Assaf, Zhivotovsky, Boris, Lam, Eric, Bozhkov, Peter V.

“…Metacaspases and paracaspases are proteases that were first identified as containing a caspase-like structural fold ( Uren et al., 2000 ). Like caspases, meta-…”
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Cryopyrin activates the inflammasome in response to toxins and ATP by Roose-Girma, Meron, Lee, Wyne P, Mariathasan, Sanjeev, Weinrauch, Yvette, Newton, Kim, Monack, Denise M, Dixit, Vishva M, O'Rourke, Karen, Weiss, David S, McBride, Jacqueline

“…A crucial part of the innate immune response is the assembly of the inflammasome, a cytosolic complex of proteins that activates caspase-1 to process the…”
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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling by Dixit, Vishva M, Wertz, Ingrid E, O'Rourke, Karen M, Zhou, Honglin, Eby, Michael, Aravind, L, Seshagiri, Somasekar, Wu, Ping, Wiesmann, Christian, Baker, Rohan, Boone, David L, Ma, Averil, Koonin, Eugene V

“…NF-κB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-1β. Failure to downregulate…”
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Apoptosis control by death and decoy receptors by Ashkenazi, Avi, Dixit, Vishva M

“…The death receptors Fas and tumor necrosis factor receptor 1 (TNFR1) trigger apoptosis upon engagement by their cognate death ligands. Recently, researchers…”
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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf by Dixit, Vishva M, Mariathasan, Sanjeev, Newton, Kim, Monack, Denise M, Vucic, Domagoj, French, Dorothy M, Lee, Wyne P, Roose-Girma, Meron, Erickson, Sharon

“…Specific adaptors regulate the activation of initiator caspases; for example, FADD and Apaf-1 engage caspases 8 and 9, respectively. The adaptors ASC, Ipaf and…”
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Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis by Mariathasan, Sanjeev, Weiss, David S, Dixit, Vishva M, Monack, Denise M

“…Francisella tularensis is a highly infectious gram-negative coccobacillus that causes the zoonosis tularemia. This bacterial pathogen causes a plague-like…”
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Death Receptors: Signaling and Modulation by Ashkenazi, Avi, Dixit, Vishva M.

“…Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's…”
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ubiquitin ligase COP1 is a critical negative regulator of p53 by Dornan, D, Wertz, I, Shimizu, H, Arnott, D, Frantz, G.D, Dowd, P, O'Rourke, K, Koeppen, H, Dixit, V.M

“…COP1 (constitutively photomorphogenic 1) is a RING-finger-containing protein that functions to repress plant photomorphogenesis, the light-mediated programme…”
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Bcl10 activates the NF-κB pathway through ubiquitination of NEMO by Dixit, Vishva M, Zhou, Honglin, Wertz, Ingrid, O'Rourke, Karen, Ultsch, Mark, Seshagiri, Somasekar, Eby, Michael, Xiao, Wei

“…The NF-κB family of transcription factors is activated in response to many stimuli, including pro-inflammatory cytokines, environmental stresses and, in the…”
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Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma by Uren, A G, O'Rourke, K, Aravind, L A, Pisabarro, M T, Seshagiri, S, Koonin, E V, Dixit, V M

“…Caspases are cysteine proteases essential to apoptosis. We have identified two families of caspase-like proteins, Paracaspases (found in metazoans and…”
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APOPTOSIS SIGNALING by Strasser, Andreas, O'Connor, Liam, Dixit, Vishva M

“…Apoptosis, a physiological process for killing cells, is critical for the normal development and function of multicellular organisms. Abnormalities in cell…”
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The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection by Roy, Craig R, Zamboni, Dario S, Kobayashi, Koichi S, Kohlsdorf, Tiana, Ogura, Yasunori, Long, E Michelle, Vance, Russell E, Kuida, Keisuke, Mariathasan, Sanjeev, Dixit, Vishva M, Flavell, Richard A, Dietrich, William F

“…Baculovirus inhibitor of apoptosis repeat-containing 1 (Birc1) proteins have homology to several germline-encoded receptors of the innate immune system…”
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β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1 by Suriben, Rowena, Kaihara, Kelly A., Paolino, Magdalena, Reichelt, Mike, Kummerfeld, Sarah K., Modrusan, Zora, Dugger, Debra L., Newton, Kim, Sagolla, Meredith, Webster, Joshua D., Liu, Jinfeng, Hebrok, Matthias, Dixit, Vishva M.

“…A variety of signals finely tune insulin secretion by pancreatic β cells to prevent both hyper-and hypoglycemic states. Here, we show that post-translational…”
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Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation by Zhou, Honglin, Monack, Denise M, Kayagaki, Nobuhiko, Wertz, Ingrid, Yin, Jianpin, Wolf, Beni, Dixit, Vishva M

“…The bacterial pathogens of the genus Yersinia, the causative agents of plague, septicemia, and gastrointestinal syndromes, use a type III secretion system to…”
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Caspase Activation: The Induced-Proximity Model by Salvesen, G S, Dixit, V M

“…Members of the caspase family of proteases transmit the events that lead to apoptosis of animal cells. Distinct members of the family are involved in both the…”
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Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase by Ruefli-Brasse, Astrid A., French, Dorothy M., Dixit, Vishva M.

“…Paracaspase (MALT1), a member of an evolutionary conserved superfamily of caspase-like proteins, has been shown to bind and colocalize with the protein Bcl10…”
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Constitutive NF-κB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity by Zhou, Honglin, Du, Ming-Qing, Dixit, Vishva M.

“…Mucosa-associated lymphoid tissue (MALT) lymphoma is a common type of lymphoma in extranodal sites. The most frequent chromosome translocation associated with…”
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