Search Results - "Dixit, D."

Caloric restriction in humans reveals immunometabolic regulators of health span by Spadaro, O, Youm, Y, Shchukina, I, Ryu, S, Sidorov, S, Ravussin, A, Nguyen, K, Aladyeva, E, Predeus, A N, Smith, S R, Ravussin, E, Galban, C, Artyomov, M N, Dixit, V D

“…The extension of life span driven by 40% caloric restriction (CR) in rodents causes trade-offs in growth, reproduction, and immune defense that make it…”
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SiGMoiD: A super-statistical generative model for binary data by Zhao, Xiaochuan, Plata, Germán, Dixit, Purushottam D

“…In modern computational biology, there is great interest in building probabilistic models to describe collections of a large number of co-varying binary…”
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Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism by Dixit, D, Ghildiyal, R, Anto, N P, Sen, E

“…Oxidative stress serves as an important regulator of both apoptosis and metabolic reprogramming in tumor cells. Chaetocin, a histone methyltransferase…”
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Recombinant transfer in the basic genome of Escherichia coli by Dixit, Purushottam D, Tin Yau Pang, F. William Studier, Sergei Maslov

“…An approximation to the ∼4-Mbp basic genome shared by 32 strains of Escherichia coli representing six evolutionary groups has been derived and analyzed…”
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Inferring Transition Rates of Networks from Populations in Continuous-Time Markov Processes by Dixit, Purushottam D, Jain, Abhinav, Stock, Gerhard, Dill, Ken A

“…We are interested inferring rate processes on networks. In particular, given a network’s topology, the stationary populations on its nodes, and a few global…”
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Mechanisms of disease: inflammasome activation and the development of type 2 diabetes by Grant, Ryan W, Dixit, Vishwa D

“…Over the recent past, the importance of aberrant immune cell activation as one of the contributing mechanisms to the development of insulin-resistance and type…”
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Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma by Ahmad, F, Dixit, D, Sharma, V, Kumar, A, Joshi, S D, Sarkar, C, Sen, E

“…Given the involvement of telomerase activation and dysregulated metabolism in glioma progression, the connection between these two critical players was…”
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Metabolically healthy and unhealthy obese – the 2013 Stock Conference report by Samocha‐Bonet, D, Dixit, V. D, Kahn, C. R, Leibel, R. L, Lin, X, Nieuwdorp, M, Pietiläinen, K. H, Rabasa‐Lhoret, R, Roden, M, Scherer, P. E, Klein, S, Ravussin, E

“…Obesity is closely associated with cardiovascular diseases and type 2 diabetes, but some obese individuals, despite having excessive body fat, exhibit…”
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Quantifying spatiotemporal variability and noise in absolute microbiota abundances using replicate sampling by Ji, Brian W., Sheth, Ravi U., Dixit, Purushottam D., Huang, Yiming, Kaufman, Andrew, Wang, Harris H., Vitkup, Dennis

“…Metagenomic sequencing has enabled detailed investigation of diverse microbial communities, but understanding their spatiotemporal variability remains an…”
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A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents by Kursawe, Romy, Dixit, Vishwa D, Scherer, Philipp E, Santoro, Nicola, Narayan, Deepak, Gordillo, Ruth, Giannini, Cosimo, Lopez, Ximena, Pierpont, Bridget, Nouws, Jessica, Shulman, Gerald I, Caprio, Sonia

“…The innate immune cell sensor leucine-rich-containing family, pyrin domain containing 3 (NLRP3) inflammasome controls the activation of caspase-1, and the…”
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GENERALIST: A latent space based generative model for protein sequence families by Akl, Hoda, Emison, Brooke, Zhao, Xiaochuan, Mondal, Arup, Perez, Alberto, Dixit, Purushottam D

“…Generative models of protein sequence families are an important tool in the repertoire of protein scientists and engineers alike. However, state-of-the-art…”
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Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans by Meydani, Simin N, Das, Sai K, Pieper, Carl F, Lewis, Michael R, Klein, Sam, Dixit, Vishwa D, Gupta, Alok K, Villareal, Dennis T, Bhapkar, Manjushri, Huang, Megan, Fuss, Paul J, Roberts, Susan B, Holloszy, John O, Fontana, Luigi

“…Calorie restriction (CR) inhibits inflammation and slows aging in many animal species, but in rodents housed in pathogen-free facilities, CR impairs immunity…”
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A maximum entropy thermodynamics of small systems by Dixit, Purushottam D

“…We present a maximum entropy approach to analyze the state space of a small system in contact with a large bath, e.g., a solvated macromolecular system. For…”
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A Simplified Approach for Determination of Inflection Points of Flattening Filter-Free Photon Beam Using In-House Developed Software and Derivation of Reference Levels by Sharma, Smriti, Dixit, D, Sharma, S, Sharma, Amit, Sahani, G, Upreti, Ritu, Kinhikar, R, Sharma, P. Dash

“…Aim: This article aimed to present the salient features of the in-house developed Java program for the determination of inflection point and dosimetric…”
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Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition by Dixit, D, Sharma, V, Ghosh, S, Mehta, V S, Sen, E

“…Glioblastoma multiforme (GBM) are resistant to TNF α -induced apoptosis and blockade of TNF α -induced NF- κ B activation sensitizes glioma cells to apoptosis…”
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Synthesis, characterization and application of green seaweed mediated silver nanoparticles (AgNPs) as antibacterial agents for water disinfection by Dixit, D, Gangadharan, D, Popat, K M, Reddy, C R K, Trivedi, M, Gadhavi, D K

“…A simple and eco-friendly method for the synthesis of hybrid bead silver nanoparticles (AgNPs) employing the aqueous extract derived from natural and renewable…”
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Inferring Microscopic Kinetic Rates from Stationary State Distributions by Dixit, Purushottam D, Dill, Ken A

“…We present a principled approach for estimating the matrix of microscopic transition probabilities among states of a Markov process, given only its stationary…”
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Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging by Ma, Xiaojun, Lin, Ligen, Qin, Guijun, Lu, Xinping, Fiorotto, Marta, Dixit, Vishwa D, Sun, Yuxiang, Stadler, Krisztian

“…Obesity is a hallmark of aging in many Western societies, and is a precursor to numerous serious age-related diseases. Ghrelin (Ghrl) , via its receptor…”
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Evolutionary capacitance and control of protein stability in protein-protein interaction networks by Dixit, Purushottam D, Maslov, Sergei

“…In addition to their biological function, protein complexes reduce the exposure of the constituent proteins to the risk of undesired oligomerization by…”
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maximum entropy framework for nonexponential distributions by Peterson, Jack, Dixit, Purushottam D., Dill, Ken A.

“…Probability distributions having power-law tails are observed in a broad range of social, economic, and biological systems. We describe here a potentially…”
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