Search Results - "Dixit, Bhavna"
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Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes
Published in Redox biology (01-02-2020)“…Mutations in mitochondrial DNA can be inherited or occur de novo leading to several debilitating myopathies with no curative option and few or no effective…”
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Rapid enrichment of mitochondria from mammalian cell cultures using digitonin
Published in MethodsX (01-01-2021)“…We describe here a simple method to enrich mitochondrial fractions from mammalian cells for downstream analyses in the lab. Mitochondria purification involves…”
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The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics
Published in Biomedicines (18-02-2022)“…Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA)…”
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Differential Transcriptomic Signatures of Small Airway Cell Cultures Derived from IPF and COVID-19-Induced Exacerbation of Interstitial Lung Disease
Published in Cells (Basel, Switzerland) (01-10-2023)“…Idiopathic pulmonary fibrosis (IPF) is a pathological condition wherein lung injury precipitates the deposition of scar tissue, ultimately leading to a decline…”
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Exogenous Expression of ATP8, a Mitochondrial Encoded Protein, From the Nucleus In Vivo
Published in Molecular therapy. Methods & clinical development (01-11-2024)Get full text
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Successful Exogenous Expression of ATP8, a Mitochondrial Encoded Protein, From the Nucleus In Vivo
Published in Innovation in aging (17-12-2021)“…Replicative errors, inefficient repair, and proximity to reactive oxygen species production sites make the mitochondrial DNA (mtDNA) susceptible to damage with…”
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Successful Exogenous Expression of ATP8, a Mitochondrial Encoded Protein, From the Nucleus In Vivo
Published in Innovation in aging (17-12-2021)“…Replicative errors, inefficient repair, and proximity to reactive oxygen species production sites make the mitochondrial DNA (mtDNA) susceptible to damage with…”
Get full text
Journal Article