Search Results - "Dix, Samuel R."
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The molecular basis of endolytic activity of a multidomain alginate lyase from Defluviitalea phaphyphila, a representative of a new lyase family, PL39
Published in The Journal of biological chemistry (29-11-2019)“…Alginate is a polymer containing two uronic acid epimers, β-d-mannuronate (M) and α-l-guluronate (G), and is a major component of brown seaweed that is…”
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Structural insights into the function of type VI secretion system TssA subunits
Published in Nature communications (12-11-2018)“…The type VI secretion system (T6SS) is a multi-protein complex that injects bacterial effector proteins into target cells. It is composed of a cell membrane…”
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Allomorphy as a mechanism of post-translational control of enzyme activity
Published in Nature communications (02-11-2020)“…Enzyme regulation is vital for metabolic adaptability in living systems. Fine control of enzyme activity is often delivered through post-translational…”
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The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family
Published in Communications biology (19-03-2021)“…In infections by apicomplexan parasites including Plasmodium , Toxoplasma gondii , and Eimeria , host interactions are mediated by proteins including families…”
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Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1
Published in Communications biology (28-03-2022)“…Burkholderia pseudomallei lethal factor 1 (BLF1) exhibits site-specific glutamine deamidase activity against the eukaryotic RNA helicase, eIF4A, thereby…”
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A New Mechanism for High-Affinity Uptake of C4-Dicarboxylates in Bacteria Revealed by the Structure of Rhodopseudomonas palustris MatC (RPA3494), a Periplasmic Binding Protein of the Tripartite Tricarboxylate Transporter (TTT) Family
Published in Journal of molecular biology (18-01-2019)“…C4-dicarboxylates play a central role in cellular physiology as key metabolic intermediates. Under aerobic conditions, they participate in the citric acid…”
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Structural basis for high‐affinity adipate binding to AdpC (RPA4515), an orphan periplasmic‐binding protein from the tripartite tricarboxylate transporter (TTT) family in Rhodopseudomonas palustris
Published in The FEBS journal (01-12-2017)“…The tripartite tricarboxylate transporter (TTT) family is a poorly characterised group of prokaryotic secondary solute transport systems, which employ a…”
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TssA from Aeromonas hydrophila: expression, purification and crystallographic studies
Published in Acta crystallographica. Section F, Structural biology communications (01-09-2018)“…TssA is a core subunit of the type VI secretion system, which is a major player in interspecies competition in Gram‐negative bacteria. Previous studies on…”
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Structural studies of the TssA and TssK subunits from the type VL secretion system
Published 01-01-2018Get full text
Dissertation