Search Results - "Dix, Kelly J."

Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men by Busby, Marjorie G, Jeffcoat, A Robert, Bloedon, LeAnne T, Koch, Matthew A, Black, Tracy, Dix, Kelly J, Heizer, William D, Thomas, Brian F, Hill, Judith M, Crowell, James A, Zeisel, Steven H

“…Soy isoflavones are potential cancer chemoprevention treatments. We conducted safety studies of purified unconjugated genistein, daidzein, and glycitein, and…”
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Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women by Bloedon, LeAnne T, Jeffcoat, A. Robert, Lopaczynski, Wlodek, Schell, Michael J, Black, Tracy M, Dix, Kelly J, Thomas, Brian F, Albright, Craig, Busby, Marjorie G, Crowell, James A, Zeisel, Steven H

“…Background: Soy isoflavones are being evaluated as chemopreventive agents for breast and other cancers. Objective: The objective was to perform safety and…”
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Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection by Thomas, Brian F, Zeisel, Steven H, Busby, Marjory G, Hill, Judith M, Mitchell, Rene’ A, Scheffler, Nicole M, Brown, Sherri S, Bloeden, Leanne T, Dix, Kelly J, Jeffcoat, A.Robert

“…Soy isoflavones are becoming of increasing interest as nutritional agents which can be used to combat osteoporosis and hyperlipidemia, and are also being…”
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INHALATION ADMINISTRATION OF ALL-TRANS-RETINOIC ACID FOR TREATMENT OF ELASTASE-INDUCED PULMONARY EMPHYSEMA IN FISCHER 344 RATS by March, Thomas H., Cossey, Patricia Y., Esparza, Dolores C., Dix, Kelly J., McDonald, Jacob D., Bowen, Larry E.

“…A past study demonstrated that all-trans-retinoic acid (ATRA) treatment by intraperitoneal injection in a rat model of elastase-induced emphysema caused tissue…”
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Comparison of inhalation toxicity studies of gentamicin in rats and dogs by Conway, Heather, Dix, Kelly J., McDonald, Jacob D., Miller, Rodney A., Wall, Henry G., Wolff, Ronald K., Reed, Matthew D.

“…Abstract Nebulized gentamicin solution was administered to rats (nose-only) and dogs (face mask) for 14 days with a 14-day recovery period. Control groups of…”
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Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 Mice by CHEN, Ling-Jen, WEGERSKI, Christopher J, KRAMER, Daniel J, THOMAS, Leslie A, MCDONALD, Jacob D, DIX, Kelly J, SANDERS, J. Michael

“…Cumene is a high-production volume chemical that has been shown to be a central nervous system depressant and has been implicated as a long-term exposure…”
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Disposition of [14C]N,N-Dimethyl-p-Toluidine in F344 Rats and B6C3F1 Mice by Dix, Kelly J., Ghanbari, Katayoon, Hedtke-Weber, Briana M.

“…N,N-Dimethyl-p-toluidine (DMPT) is used as a polymerization accelerator, in industrial glues, and as an intermediate in dye and pesticide synthesis. There is…”
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Disposition of Orally and Intravenously Administered Methyltetrahydrofuran in Rats and Mice by Henderson, Rogene F., Gurule, Mark, Hedtke-Weber, Briana M., Ghanbari, Katayoon, McDonald, Jacob D., Kracko, Dean A., Dix, Kelly J.

“…The disposition of [ 14 C]methyltetrahydrofuran ( 14 C-MTHF) in rats and mice was determined by following changes in the radioactivity in tissue and excreta…”
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Identification of Urinary Metabolites of Orally Administered N,N-Dimethyl-p-Toluidine in Male F344 Rats by Kim, Nam-Cheol, Ghanbari, Katayoon, Kracko, Dean A., Weber, Waylon M., McDonald, Jacob D., Dix, Kelly J.

“…The metabolism of orally administered N,N-dimethyl-p-toluidine (DMPT) in male F344 rats was investigated. The rat urinary metabolite profile was determined by…”
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Comparative Metabolism and Disposition of Gemfibrozil in Male and Female Sprague-Dawley Rats and Syrian golden Hamsters by DIX, K. J, COLEMAN, D. P, JEFFCOAT, A. R

“…Gemfibrozil, a human pharmaceutical agent, causes hepatomegaly and hepatic peroxisome proliferation in rats, which have been associated with…”
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Isolation and identification of novel metabolites of gemfibrozil in rat urine by THOMAS, B. F, BURGESS, J. P, COLEMAN, D. P, SCHEFFLER, N. M, JEFFCOAT, A. R, DIX, K. J

“…Gemfibrozil (GEM) is a clofibrate analog used to treat moderate to severe hypertriglyceridemias. In lab animals, GEM causes peroxisome proliferation, an effect…”
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Disposition and Metabolism of Cumene in F344 Rats and B6C3F1 MiceS by Chen, Ling-Jen, Wegerski, Christopher J., Kramer, Daniel J., Thomas, Leslie A., McDonald, Jacob D., Dix, Kelly J., Sanders, J. Michael

“…Cumene is a high-production volume chemical that has been shown to be a central nervous system depressant and has been implicated as a long-term exposure…”
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Disposition of [ super(14)C]N,N-Dimethyl-p-Toluidine in F344 Rats and B6C3F1 Mice by Dix, Kelly J, Ghanbari, Katayoon, Hedtke-Weber, Briana M

“…Deposition of [ super(14)C]N,N-dimethyl-p-toluidine (DMPT) in F344 rats and B6C3F1 mice was analyzed. The deposition of oral and in dose of [ super(14)C]DMPT…”
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Identification of Urinary Metabolites of Orally Administered N,N-Dimethyl-p- Toluidine in Male F344 Rats by Kim, Nam-Cheol, Ghanbari, Katayoon, Kracko, Dean A, Weber, Waylon M, McDonald, Jacob D, Dix, Kelly J

“…Various issues related to the identification of urinary metabolites of orally administered N,N-dimethyl-p-toluidine (DMPT) in male F344 rats were discussed…”
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Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women1,2,3 by Bloedon, LeAnne T, Jeffcoat, A Robert, Lopaczynski, Wlodek, Schell, Michael J, Black, Tracy M, Dix, Kelly J, Thomas, Brian F, Albright, Craig, Busby, Marjorie G, Crowell, James A, Zeisel, Steven H

“…Soy isoflavones are being evaluated as chemopreventive agents for breast and other cancers. The objective was to perform safety and pharmacokinetic studies of…”
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Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Editorial by BUSBY, Marjorie G, JEFFCOAT, A. Robert, ZEISEL, Steven H, ERICKSON, Kent L, BLOEDON, Leanne T, KOCH, Matthew A, BLACK, Tracy, DIX, Kelly J, HEIZER, William D, THOMAS, Brian F, HILL, Judith M, CROWELL, James A

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Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men123 by Busby, Marjorie G, Jeffcoat, A Robert, Bloedon, LeAnne T, Koch, Matthew A, Black, Tracy, Dix, Kelly J, Heizer, William D, Thomas, Brian F, Hill, Judith M, Crowell, James A, Zeisel, Steven H

“…Soy isoflavones are potential cancer chemoprevention treatments. We conducted safety studies of purified unconjugated genistein, daidzein, and glycitein, and…”
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Chapter 39 - Distribution and Pharmacokinetics by Dix, Kelly J.

“…For a pesticide to elicit toxicity, it must be transferred from the external site of exposure to the target site and achieve a sufficiently high concentration…”
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Distribution and Pharmacokinetics by Dix, Kelly

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Vehicle-dependent oral absorption and target tissue dosimetry of chloroform in male rats and female mice by Dix, Kelly J., Kedderis, Gregory L., Borghoff, Susan J.

“…Chloroform-induced toxicity in rodents depends on oral dose regimen. We evaluated the absorption and tissue dosimetry of chloroform after gavage administration…”
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