Search Results - "Diver, Melinda M."
-
1
Crystal Structure of the Calcium Release—Activated Calcium Channel Orai
Published in Science (American Association for the Advancement of Science) (07-12-2012)“…The plasma membrane protein Orai forms the pore of the calcium release—activated calcium (CRAC) channel and generates sustained cytosolic calcium signals when…”
Get full text
Journal Article -
2
Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT
Published in Nature (London) (25-01-2018)“…The X-ray structure of the integral membrane protein isoprenylcysteine carboxyl methyltransferase suggests mechanisms by which it recognizes both water-soluble…”
Get full text
Journal Article -
3
Structural insights into TRPM8 inhibition and desensitization
Published in Science (American Association for the Advancement of Science) (27-09-2019)“…The transient receptor potential melastatin 8 (TRPM8) ion channel is the primary detector of environmental cold and an important target for treating…”
Get full text
Journal Article -
4
Sensory TRP Channels in Three Dimensions
Published in Annual review of biochemistry (21-06-2022)“…Transient receptor potential (TRP) ion channels are sophisticated signaling machines that detect a wide variety of environmental and physiological signals…”
Get full text
Journal Article -
5
Mutational Analysis of the Integral Membrane Methyltransferase Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Reveals Potential Substrate Binding Sites
Published in The Journal of biological chemistry (19-09-2014)“…The eukaryotic integral membrane enzyme isoprenylcysteine carboxyl methyltransferase (ICMT) methylates the carboxylate of a lipid-modified cysteine at the C…”
Get full text
Journal Article -
6
Mapping the Substrate Binding Sites of the Integral Membrane Methyltransferase ICMT by Mutational Analysis
Published in Biophysical journal (28-01-2014)Get full text
Journal Article -
7
Mutational Analysis of the Integral Membrane Methyltransferase ICMT
Published in Biophysical journal (29-01-2013)Get full text
Journal Article