Search Results - "Dittrich, Petra S"

Microfluidics to Mimic Blood Flow in Health and Disease by Sebastian, Bernhard, Dittrich, Petra S

“…Throughout history, capillary systems have aided the establishment of the fundamental laws of blood flow and its non-Newtonian properties. The advent of…”
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Laser-assisted protein micropatterning in a thermoplastic device for multiplexed prostate cancer biomarker detection by Kling, André, Dirscherl, Lorin, Dittrich, Petra S

“…Immunoassays are frequently used for analysis of protein biomarkers. The specificity of antibodies enables parallel analysis of several target proteins, at the…”
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Lab-on-a-chip: microfluidics in drug discovery by Dittrich, Petra S, Manz, Andreas

“…Miniaturization can expand the capability of existing bioassays, separation technologies and chemical synthesis techniques. Although a reduction in size to the…”
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Identifying extracellular vesicle populations from single cells by Nikoloff, Jonas M., Saucedo-Espinosa, Mario A., Kling, André, Dittrich, Petra S.

“…Extracellular vesicles (EVs) are constantly secreted from both eukaryotic and prokaryotic cells. EVs, including those referred to as exosomes, may have an…”
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One-Dimensional Nanostructures: Microfluidic-Based Synthesis, Alignment and Integration towards Functional Sensing Devices by Xing, Yanlong, Dittrich, Petra S

“…Microfluidic-based synthesis of one-dimensional (1D) nanostructures offers tremendous advantages over bulk approaches e.g., the laminar flow, reduced sample…”
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A New Microfluidics-Based Droplet Dispenser for ICPMS by Verboket, Pascal E, Borovinskaya, Olga, Meyer, Nicole, Günther, Detlef, Dittrich, Petra S

“…In this work, a novel droplet microfluidic sample introduction system for inductively coupled plasma mass spectrometry (ICPMS) is proposed and characterized…”
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In silico design and optimization of selective membranolytic anticancer peptides by Gabernet, Gisela, Gautschi, Damian, Müller, Alex T., Neuhaus, Claudia S., Armbrecht, Lucas, Dittrich, Petra S., Hiss, Jan A., Schneider, Gisbert

“…Membranolytic anticancer peptides represent a potential strategy in the fight against cancer. However, our understanding of the underlying structure-activity…”
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A microchamber array for single cell isolation and analysis of intracellular biomolecules by Eyer, Klaus, Kuhn, Phillip, Hanke, Conni, Dittrich, Petra S

“…We present a microfluidic device that enables the determination of intracellular biomolecules in multiple single cells. The cells are individually trapped and…”
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The Effects of Shear Force Transmission Across Vesicle Membranes by Sebastian, Bernhard, Favero, Tobias, Dittrich, Petra S

“…We report a comprehensive study on mechanotransmission of shear forces across lipid bilayer membranes of giant unilamellar vesicles (GUVs). GUVs containing…”
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High-Resolution Droplet-Based Fractionation of Nano-LC Separations onto Microarrays for MALDI-MS Analysis by Küster, Simon K, Pabst, Martin, Jefimovs, Konstantins, Zenobi, Renato, Dittrich, Petra S

“…We present a robust droplet-based device, which enables the fractionation of ultralow flow rate nanoflow liquid chromatography (nano-LC) eluate streams at high…”
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Quantification of Protein Secretion from Circulating Tumor Cells in Microfluidic Chambers by Armbrecht, Lucas, Rutschmann, Ophélie, Szczerba, Barbara Maria, Nikoloff, Jonas, Aceto, Nicola, Dittrich, Petra S.

“…Cancer cells can be released from a cancerous lesion and migrate into the circulatory system, from whereon they may form metastases at distant sites. Today, it…”
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Tunable Membrane Potential Reconstituted in Giant Vesicles Promotes Permeation of Cationic Peptides at Nanomolar Concentrations by Lin, Chao-Chen, Bachmann, Michael, Bachler, Simon, Venkatesan, Koushik, Dittrich, Petra S

“…We investigate the influence of membrane potential on the permeation of cationic peptides. Therefore, we employ a microfluidic chip capable of capturing giant…”
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MALDI Mass Spectrometry on High-Density Droplet Arrays: Matrix Deposition, Selective Removal, and Recrystallization by Berlanda, Simon F., Breitfeld, Maximilian, Dittrich, Petra S.

“…High-density droplet arrays are emerging as a powerful tool for high-throughput bioanalytical applications. These arrays are formed of thousands of nanoliter…”
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Stable and Simple Immobilization of Proteinase K Inside Glass Tubes and Microfluidic Channels by Küchler, Andreas, Bleich, Julian N, Sebastian, Bernhard, Dittrich, Petra S, Walde, Peter

“…Engyodontium album proteinase K (proK) is widely used for degrading proteinaceous impurities during the isolation of nucleic acids from biological samples, or…”
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Coordination Polymer Nanofibers Generated by Microfluidic Synthesis by Puigmartí-Luis, Josep, Rubio-Martínez, Marta, Hartfelder, Urs, Imaz, Inhar, Maspoch, Daniel, Dittrich, Petra S

“…One-dimensional coordination polymer nanostructures are an emerging class of nanoscale materials with many potential applications. Here, we report the first…”
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A liposomal fluorescence assay to study permeation kinetics of drug-like weak bases across the lipid bilayer by Eyer, Klaus, Paech, Franziska, Schuler, Friedrich, Kuhn, Phillip, Kissner, Reinhard, Belli, Sara, Dittrich, Petra S., Krämer, Stefanie D.

“…Lipid bilayer permeation is considered the major route for in vivo barrier passage of drugs. Despite this fact, no technique is currently available to measure…”
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An Integrated Microfluidic System for Reaction, High-Sensitivity Detection, and Sorting of Fluorescent Cells and Particles by Dittrich, Petra S, Schwille, Petra

“…Presented is a novel approach for an integrated micro total analysis system (μTAS) based on a microfluidic on-chip device that supports ultrasensitive confocal…”
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A Microfluidic Vesicle Screening Platform: Monitoring the Lipid Membrane Permeability of Tetracyclines by Kuhn, Phillip, Eyer, Klaus, Allner, Steffen, Lombardi, Dario, Dittrich, Petra S

“…For many drugs including antibiotics such as tetracyclines it is crucial that the molecule has the ability to quickly and passively permeate lipid membranes…”
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Recent Advances in the Analysis of Single Cells by Armbrecht, Lucas, Dittrich, Petra S

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A Microfluidic Approach for the Formation of Conductive Nanowires and Hollow Hybrid Structures by Puigmartí-Luis, Josep, Schaffhauser, Daniel, Burg, Brian R., Dittrich, Petra S.

“…A facile fabrication process for micro‐ and nanometer‐scale hybrid structures employing a microfluidic reactor is described. The unique properties of…”
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