Search Results - "Distinto, S."

Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity by Paulis, A., Onali, A., Vidalain, P.O., Lotteau, V., Jaquemin, C., Corona, A., Distinto, S., Delogu, G.L., Tramontano, E.

“…•Benzofuran derivatives were shown to induce IFN-I expression in a STING-dependent luciferase assay.•Activity as STING agonist was confirmed by mutagenesis…”
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Enhancing drug discovery through in silico screening: strategies to increase true positives retrieval rates by Kirchmair, J, Distinto, S, Schuster, D, Spitzer, G, Langer, T, Wolber, G

“…Computational chemistry software for lead discovery has become well established in pharmaceutical industry and has found its way to the desktop computers of…”
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Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase by Maccioni, E., Alcaro, S., Orallo, F., Cardia, M.C., Distinto, S., Costa, G., Yanez, M., Sanna, M.L., Vigo, S., Meleddu, R., Secci, D.

“…Some differently substituted 3-aryl-4,5-dihydropyrazoles-1-carbothioamides have been synthesised with the aim to investigate their monoamine oxidase inhibitory…”
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Synthesis and biological activity evaluation of differently substituted 1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carboxamides and -carbothioamides by Cardia, M. C., Distinto, S., Maccioni, E., Bonsignore, L., Delogu, A.

“…Differently substituted phthalic anhydrides can react either with semicarbazide or thiosemicarbazide to give respectively…”
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Synthesis and anti-microbial activity evaluation of some new 1-benzoyl-isothiosemicarbazides by Plumitallo, A., Cardia, M.C., Distinto, S., DeLogu, A., Maccioni, E.

“…The synthesis of some aroylisothiosemicarbazides was accomplished and their biological activity against bacteria, fungi, and mycobacteria was investigated…”
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An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues by Maccioni, E, Cardia, M.C, Distinto, S, Bonsignore, L, De Logu, A

“…Several arylideneisothiosemicarbazones and arylidenehydrazothiazoles have been synthesised to obtain new antimicrobial agents. Their activity against both…”
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Synthesis, Molecular Modeling Studies, and Selective Inhibitory Activity against Monoamine Oxidase of 1-Thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole Derivatives by Chimenti, Franco, Maccioni, Elias, Secci, Daniela, Bolasco, Adriana, Chimenti, Paola, Granese, Arianna, Befani, Olivia, Turini, Paola, Alcaro, Stefano, Ortuso, Francesco, Cirilli, Roberto, La Torre, Francesco, Cardia, Maria C, Distinto, Simona

“…A novel series of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole derivatives have been synthesized and investigated for the ability to inhibit…”
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