Search Results - "Disterhoft, J F"

Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease by Kaczorowski, C.C, Sametsky, E, Shah, S, Vassar, R, Disterhoft, J.F

“…Abstract Accumulations of β-amyloid (Aβ) contribute to neurological deficits associated with Alzheimer's disease (AD). The effects of Aβ on basal neuronal…”
Get full text

Positive emotional learning is regulated in the medial prefrontal cortex by GluN2B-containing NMDA receptors by Burgdorf, J, Kroes, R.A, Weiss, C, Oh, M.M, Disterhoft, J.F, Brudzynski, S.M, Panksepp, J, Moskal, J.R

“…Abstract In rats, hedonic ultrasonic vocalizations (USVs) is a validated model of positive affect and is best elicited by rough-and-tumble play. Here we report…”
Get full text

Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum by Geinisman, Y., Ganeshina, O., Yoshida, R., Berry, R.W., Disterhoft, J.F., Gallagher, M.

“…The aim of this study was to determine whether spatial learning deficits in aged rats are associated with a loss of hippocampal synapses. The Morris water maze…”
Get full text

Cortical Involvement in Acquisition and Extinction of Trace Eyeblink Conditioning by Weible, A. P, McEchron, M. D, Disterhoft, J. F

“…Previous studies have implicated 2 cortical regions interconnected with the hippocampal formation, the retrosplenial cortex (RSC) and the medial prefrontal…”
Get full text

Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE by WILCOXON, J. S, KUO, A. G, DISTERHOFT, J. F, REDEI, E. E

“…Children prenatally exposed to alcohol typically exhibit behavioral abnormalities, including hyperactivity, learning deficits, and an increased prevalence of…”
Get full text

Connections of the caudal anterior cingulate cortex in rabbit: Neural circuitry participating in the acquisition of trace eyeblink conditioning by Weible, A.P, Weiss, C, Disterhoft, J.F

“…Abstract The caudal anterior cingulate cortex (cAC) is an essential component of the circuitry involved in acquisition of forebrain-dependent trace eyeblink…”
Get full text

Trace eyeblink conditioning is hippocampally dependent in mice by Tseng, W., Guan, R., Disterhoft, J.F., Weiss, C.

“…The goal of this study was to determine whether trace eyeblink conditioning is a hippocampally dependent associative learning task in the mouse. First, we…”
Get full text

Comparisons of dorsal and ventral hippocampus cornu ammonis region 1 pyramidal neuron activity during trace eye-blink conditioning in the rabbit by Weible, A.P., O’Reilly, J.-A., Weiss, C., Disterhoft, J.F.

“…Previous studies demonstrating a critical role of the hippocampus during trace eye-blink conditioning have focused primarily upon the dorsal portion of the…”
Get full text

Transient changes in excitability of rabbit CA3 neurons with a time course appropriate to support memory consolidation by Thompson, L T, Moyer, Jr, J R, Disterhoft, J F

“…1. The excitability of CA3 pyramidal neurons was assessed with intracellular recordings in hippocampal slices from behaviorally naive rabbits. CA3 pyramidal…”
Get more information

Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat by Weiss, Craig, Bouwmeester, Hans, Power, John M, Disterhoft, John F

“…The effect of hippocampal aspiration lesions on trace eyeblink conditioning was examined in young, freely-moving F1 hybrid rats (Fisher 344×Brown Norway). Rats…”
Get full text

Galantamine increases excitability of CA1 hippocampal pyramidal neurons by Oh, M.M., Wu, W.W., Power, J.M., Disterhoft, J.F.

“…Galantamine is a third generation cholinesterase inhibitor and an allosteric potentiating ligand of nicotinic acetylcholine receptors. It enhances learning in…”
Get full text

Awareness in Classical Differential Eyeblink Conditioning in Young and Aging Humans by Knuttinen, M.-G, Power, J. M, Preston, A. R, Disterhoft, J. F

“…The role of awareness and its impact on learning the conditioned eyeblink response was investigated in both trace and delay discrimination eyeblink…”
Get full text

Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner by Moyer, Jr, J R, Thompson, L T, Black, J P, Disterhoft, J F

“…1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young…”
Get more information

The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus by Burgdorf, J, Zhang, X.-l, Weiss, C, Gross, A, Boikess, S.R, Kroes, R.A, Khan, M.A, Burch, R.M, Rex, C.S, Disterhoft, J.F, Stanton, P.K, Moskal, J.R

“…Highlights • GLYX-13 produces antidepressant-like effects for ⩾1 week following a single dose. • GLYX-13 facilitates learning and memory for ⩾1 week following…”
Get full text

Lesions of the Caudal Area of Rabbit Medial Prefrontal Cortex Impair Trace Eyeblink Conditioning by Kronforst-Collins, Michelle A., Disterhoft, John F.

“…The dorsolateral prefrontal cortex of the primate is an area known to be important for memory. Since the discovery of a homologous area in subprimate mammals,…”
Get full text

Impaired Eyeblink Conditioning and Decreased Hippocampal Volume in PDAPP V717F Mice by Weiss, C., Venkatasubramanian, P.N., Aguado, A.S., Power, J.M., Tom, B.C., Li, L., Chen, K.S., Disterhoft, J.F., Wyrwicz, A.M.

“…We examined heterozygous transgenic (Tg) mice that overexpress V717F amyloid precursor protein (APP) for delay eyeblink conditioning (EBC) and hippocampal…”
Get full text

Impaired Trace Eyeblink Conditioning in Bilateral, Medial-Temporal Lobe Amnesia by McGlinchey-Berroth, Regina, Carrillo, Maria C, Gabrieli, John D. E, Brawn, Catherine M, Disterhoft, John F

“…Trace eyeblink classical conditioning was assessed in patients with bilateral medial-temporal amnesia and matched control participants who had previously shown…”
Get full text

Eyeblink Conditioning in the Rabbit (Oryctolagus cuniculus ) With Stimulation of the Mystacial Vibrissae as a Conditioned Stimulus by Das, S, Weiss, C, Disterhoft, J. F

“…Eyeblink conditioning is a well-understood paradigm for the study of learning and memory and has been successfully employed with the use of auditory and visual…”
Get full text

Trace Eyeblink Conditioning in the Freely Moving Rat: Optimizing the Conditioning Parameters by Weiss, C, Knuttinen, M.-G, Power, J. M, Patel, R. I, O'Connor, M. S, Disterhoft, J. F

“…Trace eyeblink conditioning (EBC) parameters, with an airpuff unconditioned stimulus, were examined in male Fischer 344 × Brown Norway F1 rats. Integrated…”
Get full text

The calcium rationale in aging and Alzheimer's disease. Evidence from an animal model of normal aging by Disterhoft, J F, Moyer, Jr, J R, Thompson, L T

Get more information