Search Results - "Distel, B"

The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import of PTS1-containing proteins by Elgersma, Ype, Kwast, Liane, Klein, André, Voorn-Brouwer, Tineke, van den Berg, Marlene, Metzig, Brigitte, Twan America, Tabak, Henk F., Distel, Ben

“…We identified a Saccharomyces cerevisiae peroxisomal membrane protein, Pex13p, that is essential for protein import. A point mutation in the COOH-terminal Src…”
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ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae by Hettema, E.H, Roermund, C.W.T. van, Distel, B, Berg, M. van den, Vilela, C, Rodrigues-Pousada, C, Wanders, R.J.A, Tabak, H.F

“…Peroxisomes of Saccharomyces cerevisiae are the exclusive site of fatty acid beta-oxidation. We have found that fatty acids reach the peroxisomal matrix via…”
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Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner by Bottger, G, Barnett, P, Klein, A T, Kragt, A, Tabak, H F, Distel, B

“…A number of peroxisome-associated proteins have been described that are involved in the import of proteins into peroxisomes, among which is the receptor for…”
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Peroxisomal membrane proteins are properly targeted to peroxisomes in the absence of COPI- and COPII-mediated vesicular transport by Voorn-Brouwer, T, Kragt, A, Tabak, H F, Distel, B

“…The classic model for peroxisome biogenesis states that new peroxisomes arise by the fission of pre-existing ones and that peroxisomal matrix and membrane…”
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PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae by Leij, I. van der, Franse, M.M, Elgersma, Y, Distel, B, Tabak, H.F

“…pas mutants of Saccharomyces cerevisiae are disturbed in peroxisome assembly (pas) and proliferation. Here we report the characterization of the PAS10 gene and…”
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Differential Protein Import Deficiencies in Human Peroxisome Assembly Disorders by Motley, Alison, Hettema, Ewald, Distel, Ben, Tabak, Henk

“…Two peroxisome targeting signals (PTSs) for matrix proteins have been well defined to date. PTS1 comprises a COOH-terminal tripeptide, SKL, and has been found…”
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Peroxisomal protein import is conserved between yeast, plants, insects and mammals by Gould, S.J., Keller, G.A., Schneider, M., Howell, S.H., Garrard, L.J., Goodman, J.M., Distel, B., Tabak, H., Subramani, S.

“…We have previously demonstrated that firefly luciferase can be imported into peroxisomes of both insect and mammalian cells. To determine whether the process…”
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Formation of DNA double-strand breaks and DNA–protein crosslinks by irradiation of DNA in the presence of a protein by Distel, L., Distel, B., Schüssler, H.

“…Double-stranded DNA and serum albumin were irradiated with X-rays in different phosphate solutions under N 2, N 2O and air. Double-strand breaks (dsb) were…”
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An efficient positive selection procedure for the isolation of peroxisomal import and peroxisome assembly mutants of Saccharomyces cerevisiae by Elgersma, Y, Berg, M. van den, Tabak, H.F, Distel, B

“…To study peroxisome biogenesis, we developed a procedure to select for Saccharomyces cerevisiae mutants defective in peroxisomal protein import or peroxisome…”
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Transactions at the peroxisomal membrane by Distel, B, Braakman, I, Elgersma, Y, Tabak, H F

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Endoplasmic Reticulum-directed Pex3p Routes to Peroxisomes and Restores Peroxisome Formation in a Saccharomyces cerevisiae pex3Δ Strain by Kragt, Astrid, Voorn-Brouwer, Tineke, van den Berg, Marlene, Distel, Ben

“…Recent studies on the sorting of peroxisomal membrane proteins challenge the long-standing model in which peroxisomes are considered to be autonomous…”
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The Saccharomyces cerevisiae Peroxisomal Import Receptor Pex5p Is Monoubiquitinated in Wild Type Cells by Astrid Kragt, Tineke Voorn-Brouwer, Marlene van den Berg, Ben Distel

“…Pex5p is a mobile receptor for peroxisomal targeting signal type I-containing proteins that cycles between the cytoplasm and the peroxisome. Here we show that…”
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Import of alcohol oxidase into peroxisomes of Saccharomyces cerevisiae by Distel, B., Veenhuis, M., Tabak, H. F.

“…Saccharomyces cerevisiae is unable to grow on methanol because it lacks the enzymes required for its metabolism. To study the possibility of whether or not the…”
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Peroxisome isolation by Distel, B, van der Leij, I, Kos, W

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Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments by Leyte, A, Mertens, K, Distel, B, Evers, R F, De Keyzer-Nellen, M J, Groenen-Van Dooren, M M, De Bruin, J, Pannekoek, H, Van Mourik, J A, Verbeet, M P

“…The epitopes of four monoclonal antibodies against coagulation Factor VIII were mapped with the use of recombinant DNA techniques. Full-length Factor VIII cDNA…”
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Molecular basis of rhizomelic chondrodysplasia punctata type I: High frequency of the Leu‐292 Stop mutation in 38 patients by Brites, P., Motley, A., Hogenhout, E., Hettema, E., Wijburg, F., Heijmans, H. S. A., Tabak, H. F., Distel, B., Wanders, R. J. A.

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Pex10p functions as an E sub(3) ligase for the Ubc4p-dependent ubiquitination of Pex5p by Williams, C, van den Berg, M, Geers, E, Distel, B

“…The Saccharomyces cerevisiae (Sc) PTS1 import receptor Pex5p is modified by ubiquitin, both in an Ubc4p-dependent and a Pex4p (Ubc10p)-dependent manner. Both…”
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Involvement of the endoplasmic reticulum in peroxisome formation by Geuze, Hans J, Murk, Jean Luc, Stroobants, An K, Griffith, Janice M, Kleijmeer, Monique J, Koster, Abraham J, Verkleij, Arie J, Distel, Ben, Tabak, Henk F

“…The traditional view holds that peroxisomes are autonomous organelles multiplying by growth and division. More recently, new observations have challenged this…”
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Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins by Hettema, E.H, Girzalsky, W, Berg, M. van den, Erdmann, R, Distel, B

“…The mechanisms by which peroxisomal membrane proteins (PMPs) are targeted to and inserted into membranes are unknown, as are the required components. We show…”
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Transcriptional regulation of genes encoding proteins involved in biogenesis of peroxisomes in Saccharomyces cerevisiae by Einerhand, A W, Van Der Leij, I, Kos, W T, Distel, B, Tabak, H F

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