Search Results - "Dirstine, Tanner"
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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Published in Cell reports (Cambridge) (27-02-2018)“…The development of clinically viable delivery methods presents one of the greatest challenges in the therapeutic application of CRISPR/Cas9 mediated genome…”
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Recovery of the biphasic hypoxic ventilatory response in neonatal rats after chronic hyperoxia
Published in Respiratory physiology & neurobiology (01-01-2023)“…Newborn mammals exhibit biphasic hypoxic ventilatory responses (HVR) characterized by an initial increase in ventilation and a secondary ventilatory…”
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Novel Human Factor VIII Variant with Impaired Intracellular Processing Exhibits Enhanced In Vivo Efficacy
Published in Blood (02-12-2016)“…During intracellular processing, B-domain deleted human factor VIII (hFVIII-BDD) undergoes proteolysis at multiple sites with the most predominant cleavage at…”
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