Search Results - "Dirks, A. (Ton) J"
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Bioconjugation with Strained Alkenes and Alkynes
Published in Accounts of chemical research (20-09-2011)“…The structural complexity of molecules isolated from biological sources has always served as an inspiration for organic chemists. Since the first synthesis of…”
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Metal-Free Triazole Formation as a Tool for Bioconjugation
Published in Chembiochem : a European journal of chemical biology (03-09-2007)“…Who needs copper? There is a strong demand for ligation reactions that proceed spontaneously, selectively, and under physiological conditions. To meet these…”
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Monitoring Protein−Polymer Conjugation by a Fluorogenic Cu(I)-Catalyzed Azide−Alkyne 1,3-Dipolar Cycloaddition
Published in Bioconjugate chemistry (17-06-2009)“…The Cu(I)-catalyzed azide−alkyne cycloaddition (CuAAC) has recently proven to be a powerful synthetic tool in various fields of chemistry, including…”
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Controlled Integration of Polymers into Viral Capsids
Published in Biomacromolecules (09-11-2009)“…In this paper, we describe the controlled incorporation of two synthetic polymers with different structures in the cowpea chlorotic mottle virus (CCMV) capsid…”
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5
Application of Metal-Free Triazole Formation in the Synthesis of Cyclic RGD-DTPA Conjugates
Published in Chembiochem : a European journal of chemical biology (21-07-2008)“…The tandem 1,3‐dipolar cycloaddition‐retro‐Diels–Alder (tandem crDA) reaction is presented as a versatile method for metal‐free chemoselective conjugation of a…”
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6
Protein-Polymer Hybrid Amphiphiles
Published in Advanced materials (Weinheim) (17-10-2008)“…Biohybrid amphiphiles composed of a protein head group and a hydrophobic polymer tail self‐assemble in water in a similar way as low molecular weight…”
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Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction
Published in Chemical communications (Cambridge, England) (07-09-2005)“…Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed…”
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Unusual rate enhancement in the thymine assisted ATRP process of adenine monomers
Published in Polymer (Guilford) (08-09-2005)“…Thymine and adenine monomers were synthesized and polymerized using ATRP in a controlled fashion. In addition a thymine functionalized block copolymer was…”
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From (bio)Molecules to Biohybrid Materials with the Click Chemistry Approach
Published in QSAR & combinatorial science (01-12-2007)“…In order to construct biologically active materials for applications in nanotechnology and medicine, materials scientists have extensively explored the use of…”
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