The feasibility of identifying children with primary immunodeficiency disorders: Preparation for the polio post-eradication era in Bangladesh

Highlights ► Physicians from five tertiary hospitals clinically suspected PIDD patients. ► Age-specific QIG testing was used for laboratory confirmation. ► Among 13 suspected PIDD cases, 6 were laboratory confirmed. ► None of them were excreting iVDPV. ► Low income counties like Bangladesh need to a...

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Bibliographic Details
Published in:	Vaccine Vol. 30; no. 36; pp. 5396 - 5400
Main Authors:	Sazzad, Hossain M.S, Rainey, Jeanette J, Mach, Ondrej, Sutter, Roland, Diordista, Serguei, Kawser, Choudhury A, Mobarak, Reaz, Alam, Didarul, Chowdhury, Mahmood A, Hossain, M. Jahangir, Hasan, A.S.M. Mainul, Luby, Stephen P
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 03-08-2012 Elsevier Limited
Subjects:	Age Allergy and Immunology Antibiotics Antibodies, Viral - blood Antibodies, Viral - immunology Bangladesh Child Child, Preschool children Children & youth Enterovirus C excretion Family medical history feces Female guidelines Health facilities hospitals Humans Immunodeficiency-associated vaccine-derived poliovirus (iVDPV) immunoglobulins Immunologic Deficiency Syndromes - diagnosis immunosuppression (physiological) Infant Infant, Newborn infants Infections Laboratories Male Malnutrition monitoring Oral polio vaccine Patients Pediatrics people Polio Poliomyelitis Poliovirus - immunology Poliovirus Vaccine, Inactivated - adverse effects Poliovirus Vaccine, Inactivated - immunology Poliovirus Vaccine, Oral - adverse effects Poliovirus Vaccine, Oral - immunology Primary immunodeficiency disorder public health recruitment risk risk estimate Vaccine associated paralytic polio Vaccine-derived poliovirus (VDPV) Vaccines Virus Activation - immunology viruses watersheds World Health Organization Bangladesh Immunodeficiency-associated vaccine-derived poliovirus (iVDPV) Polio Vaccine-derived poliovirus (VDPV) Oral polio vaccine Primary immunodeficiency disorder Vaccine associated paralytic polio
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Summary:	Highlights ► Physicians from five tertiary hospitals clinically suspected PIDD patients. ► Age-specific QIG testing was used for laboratory confirmation. ► Among 13 suspected PIDD cases, 6 were laboratory confirmed. ► None of them were excreting iVDPV. ► Low income counties like Bangladesh need to adopt feasible strategies to identify PIDD patients.
Bibliography:	http://dx.doi.org/10.1016/j.vaccine.2012.06.017 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.06.017