Search Results - "Dionne, Christopher J."

Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage by Anderson, Michele K, Weiss, Angela H, Hernandez-Hoyos, Gabriela, Dionne, Christopher J, Rothenberg, Ellen V

“…The essential hematopoietic transcription factor PU.1 is expressed in multipotent thymic precursors but downregulated during T lineage commitment. The…”
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Subversion of T lineage commitment by PU.1 in a clonal cell line system by Dionne, Christopher J., Tse, Kevin Y., Weiss, Angela H., Franco, Christopher B., Wiest, David L., Anderson, Michele K., Rothenberg, Ellen V.

“…Specification of mammalian T lymphocytes involves prolonged developmental plasticity even after lineage-specific gene expression begins. Expression of…”
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Definition of Regulatory Network Elements for T Cell Development by Perturbation Analysis with PU.1 and GATA-3 by Anderson, Michele K., Hernandez-Hoyos, Gabriela, Dionne, Christopher J., Arias, Alexandra M., Chen, Dan, Rothenberg, Ellen V.

“…PU.1 and GATA-3 are transcription factors that are required for development of T cell progenitors from the earliest stages. Neither one is a simple positive…”
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Lineage plasticity and commitment in T-cell development by Rothenberg, Ellen V., Dionne, Christopher J.

“…The earliest stages of intrathymic T‐cell development include not only the acquisition of T‐cell characteristics but also programmed loss of potentials for B,…”
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Lineage plasticity and commitment in T-cell development: Hematopoietic stem cell biology & lineage plasticity by ROTHENBERG, Ellen V, DIONNE, Christopher J

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