Search Results - "Dionellis, Vasilis S."

Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits by Rossetti, Giacomo G., Ossorio, Marianna A., Rempel, Stephan, Kratzel, Annika, Dionellis, Vasilis S., Barriot, Samia, Tropia, Laurence, Gorgulla, Christoph, Arthanari, Haribabu, Thiel, Volker, Mohr, Peter, Gamboni, Remo, Halazonetis, Thanos D.

“…M pro , the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is essential for the viral life cycle. Accordingly, several…”
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Genome Sequencing of five Lacticaseibacillus Strains and Analysis of Type I and II Toxin-Antitoxin System Distribution by Levante, Alessia, Lazzi, Camilla, Vatsellas, Giannis, Chatzopoulos, Dimitris, Dionellis, Vasilis S, Makrythanasis, Periklis, Neviani, Erasmo, Folli, Claudia

“…The analysis of bacterial genomes is a potent tool to investigate the distribution of specific traits related to the ability of surviving in particular…”
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Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal Tissue by Lugli, Natalia, Dionellis, Vasilis S., Ordóñez-Morán, Paloma, Kamileri, Irene, Sotiriou, Sotirios K., Huelsken, Joerg, Halazonetis, Thanos D.

“…The most prevalent single-nucleotide substitution (SNS) found in cancers is a C-to-T substitution in the CpG motif. It has been proposed that many of these…”
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Transcription–replication conflicts underlie sensitivity to PARP inhibitors by Petropoulos, Michalis, Karamichali, Angeliki, Rossetti, Giacomo G., Freudenmann, Alena, Iacovino, Luca G., Dionellis, Vasilis S., Sotiriou, Sotirios K., Halazonetis, Thanos D.

“…An important advance in cancer therapy has been the development of poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of homologous recombination…”
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Non-covalent SARS-CoV-2 M pro inhibitors developed from in silico screen hits by Rossetti, Giacomo G, Ossorio, Marianna A, Rempel, Stephan, Kratzel, Annika, Dionellis, Vasilis S, Barriot, Samia, Tropia, Laurence, Gorgulla, Christoph, Arthanari, Haribabu, Thiel, Volker, Mohr, Peter, Gamboni, Remo, Halazonetis, Thanos D

“…M , the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is essential for the viral life cycle. Accordingly, several groups…”
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Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells by Groelly, Florian J., Dagg, Rebecca A., Petropoulos, Michalis, Rossetti, Giacomo G., Prasad, Birbal, Panagopoulos, Andreas, Paulsen, Teressa, Karamichali, Angeliki, Jones, Samuel E., Ochs, Fena, Dionellis, Vasilis S., Puig Lombardi, Emilia, Miossec, Matthieu J., Lockstone, Helen, Legube, Gaëlle, Blackford, Andrew N., Altmeyer, Matthias, Halazonetis, Thanos D., Tarsounas, Madalena

“…Aberrant replication causes cells lacking BRCA2 to enter mitosis with under-replicated DNA, which activates a repair mechanism known as mitotic DNA synthesis…”
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Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage by Petropoulos, Michalis, Champeris Tsaniras, Spyridon, Nikou, Sofia, Maxouri, Styliani, Dionellis, Vasilis S, Kalogeropoulou, Argyro, Karamichali, Angeliki, Ioannidis, Konstantinos, Danalatos, Iosif‐Rodolfos, Obst, Mandy, Naumann, Ronald, Delinasios, George J, Gorgoulis, Vassilis G, Roukos, Vassilis, Anastassiadis, Konstantinos, Halazonetis, Thanos D, Bravou, Vasiliki, Lygerou, Zoi, Taraviras, Stavros

“…Chromatin licensing and DNA replication factor 1 (CDT1), a protein of the pre‐replicative complex, is essential for loading the minichromosome maintenance…”
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Beating cancer one carbon at a time by Dionellis, Vasilis S, Halazonetis, Thanos D

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Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes by Dionellis, Vasilis S, Norkin, Maxim, Karamichali, Angeliki, Rossetti, Giacomo G, Huelsken, Joerg, Ordonez-Moran, Paloma, Halazonetis, Thanos D

“…The genomes of many human CRCs have been sequenced, revealing a large number of genetic alterations. However, the molecular mechanisms underlying the…”
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Notch controls urothelial integrity in the mouse bladder by Paraskevopoulou, Varvara, Bonis, Vangelis, Dionellis, Vasilis S, Paschalidis, Nikolaos, Melissa, Pelagia, Chavdoula, Evangelia, Vasilaki, Eleni, Pateras, Ioannis S, Klinakis, Apostolos

“…The Notch signaling pathway mediates cell-cell communication regulating cell differentiation and proliferation and cell fate decisions in various tissues. In…”
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