Search Results - "Dion, Morton"

Surgical site infection and costs in low- and middle-income countries: A systematic review of the economic burden by Monahan, Mark, Jowett, Susan, Pinkney, Thomas, Brocklehurst, Peter, Morton, Dion G, Abdali, Zainab, Roberts, Tracy E

“…Background Surgical site infection (SSI) is a worldwide problem which has morbidity, mortality and financial consequences. The incidence rate of SSI is high in…”
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Global guidance for surgical care during the COVID-19 pandemic by Bhangu, Aneel, Lawani, Ismail, Ng‐Kamstra, Joshua S, Wang, Yanfeng, Chan, Albert, Futaba, Kaori, Ng, Simon, Ebele, Emery, Lederhuber, Hans, Tabiri, Stephen, Ghosh, Dhruv, Gallo, Gaetano, Pata, Francesco, Di Saverio, Salomone, Spinelli, Antonino, Medina, Antonio Ramos‐De, Ademuyiwa, Adesoji O, Akinbode, Gbemisola, Ingabire, JC Allen, Ntirenganya, Faustin, Kamara, Thaim B, Goh, Minghui, Moore, Rachel, Kim, Hye Jin, Lee, Suk‐Hwan, Minaya‐Bravo, Ana, Abbott, Tom, Chakrabortee, Sohini, Denning, Max, Fitzgerald, J Edward, Glasbey, James, Griffiths, Ewen, Halkias, Constantine, Harrison, Ewen M, Jones, Conor S, Kinross, James, Lawday, Samuel, Li, Elizabeth, Markar, Sheraz, Morton, Dion G, Nepogodiev, Dmitri, Pinkney, Thomas D, Simoes, Joana, Warren, Oliver, Wong, Danny JN, Bankhead‐Kendall, Brittany, Breen, Kerry A, Davidson, Giana H, Kaafarani, Haytham, Keller, Deborah S, Mazingi, Dennis, Kamarajah, Sivesh K, Blackwell, Sue, Dames, Nicola

“…Abstract Background Surgeons urgently need guidance on how to deliver surgical services safely and effectively during the COVID-19 pandemic. The aim was to…”
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Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial by Morton, Dion, Seymour, Matthew, Magill, Laura, Handley, Kelly, Glasbey, James, Glimelius, Bengt, Palmer, Andy, Seligmann, Jenny, Laurberg, Søren, Murakami, Keigo, West, Nick, Quirke, Philip, Gray, Richard

“…Neoadjuvant chemotherapy (NAC) has potential advantages over standard postoperative chemotherapy for locally advanced colon cancer but requires formal…”
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Global burden of postoperative death by Nepogodiev, Dmitri, Martin, Janet, Biccard, Bruce, Makupe, Alex, Bhangu, Aneel, Nepogodiev, Dmitri, Martin, Janet, Biccard, Bruce, Makupe, Alex, Ademuyiwa, Adesoji, Adisa, Adewale Oluseye, Aguilera, Maria-Lorena, Chakrabortee, Sohini, Fitzgerald, J. Edward, Ghosh, Dhruva, Glasbey, James C., Harrison, Ewen M., Ingabire, J.C. Allen, Salem, Hosni, Lapitan, Marie Carmela, Lawani, Ismail, Lissauer, David, Magill, Laura, Moore, Rachel, Osei-Bordom, Daniel C., Pinkney, Thomas D., Qureshi, Ahmad Uzair, Ramos-De la Medina, Antonio, Rayne, Sarah, Sundar, Sudha, Tabiri, Stephen, Verjee, Azmina, Yepez, Raul, Garden, O. James, Lilford, Richard, Brocklehurst, Peter, Morton, Dion G., Bhangu, Aneel

“…Little is known about the quality of surgery globally because robust reports of postoperative death rates are available for only 29 countries.2 The rate of…”
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Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy by Venn, Mary L, Knowles, Charles H, Li, Elizabeth, Glasbey, James, Morton, Dion G, Hooper, Richard

“…Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic…”
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Embracing change: a collective call to address multimorbidity in surgical pathways by Kamarajah, Sivesh K., Bhangu, Aneel, Ahuja, Shalini, Dhesi, Jugdeep, Yeung, Joyce, Nirantharakumar, Krishnarajah, Pinkney, Thomas, Morton, Dion G.

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Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER by Gilligan, Lorna C, Rahman, Habibur P, Hewitt, Anne-Marie, Sitch, Alice J, Gondal, Ali, Arvaniti, Anastasia, Taylor, Angela E, Read, Martin L, Morton, Dion G, Foster, Paul A

“…Abstract Context Estrogens affect the incidence and progression of colorectal cancer (CRC), although the precise molecular mechanisms remain ill-defined…”
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Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa by Kachapila, Mwayi, Ademuyiwa, Adesoji O, Biccard, Bruce M, Ghosh, Dhruva N, Glasbey, James, Monahan, Mark, Moore, Rachel, Morton, Dion G, Oppong, Raymond, Pearse, Rupert, Roberts, Tracy E

“…Background Pneumonia is a common and severe complication of abdominal surgery, it is associated with increased length of hospital stay, healthcare costs, and…”
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A systematic review of systematic reviews and panoramic meta-analysis: staples versus sutures for surgical procedures by Hemming, Karla, Pinkney, Thomas, Futaba, Kay, Pennant, Mary, Morton, Dion G, Lilford, Richard J

“…To systematically evaluate the evidence across surgical specialties as to whether staples or sutures better improve patient and provider level outcomes. A…”
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The molecular landscape of well differentiated retroperitoneal liposarcoma by Tyler, Robert, Dilworth, Mark P, James, Jonathan, Blakeway, Daniel, Stockton, Joanne D, Morton, Dion G, Taniere, Phillipe, Gourevitch, David, Desai, Anant, Beggs, Andrew D

“…Well differentiated liposarcoma (WD‐LPS) is a relatively rare tumour, with fewer than 50 cases occurring per year in the UK. These tumours are both…”
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A Randomized Trial of Rofecoxib for the Chemoprevention of Colorectal Adenomas by Baron, John A., Sandler, Robert S., Bresalier, Robert S., Quan, Hui, Riddell, Robert, Lanas, Angel, Bolognese, James A., Oxenius, Bettina, Horgan, Kevin, Loftus, Susan, Morton, Dion G.

“…Background & Aims: In human and animal studies, nonsteroidal anti-inflammatory drugs have been associated with a reduced risk of colorectal neoplasia. Although…”
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Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial by Atkin, Wendy, Prof, Dadswell, Edward, MSci, Wooldrage, Kate, MSc, Kralj-Hans, Ines, PhD, von Wagner, Christian, PhD, Edwards, Rob, PhD, Yao, Guiqing, PhD, Kay, Clive, Prof, Burling, David, FRCR, Faiz, Omar, FRCS, Teare, Julian, FRCP, Lilford, Richard J, Prof, Morton, Dion, Prof, Wardle, Jane, Prof, Halligan, Steve, Prof

“…Summary Background Colonoscopy is the gold-standard test for investigation of symptoms suggestive of colorectal cancer; computed tomographic colonography (CTC)…”
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Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial by Baron, John A, Prof, Sandler, Robert S, Prof, Bresalier, Robert S, Prof, Lanas, Angel, Prof, Morton, Dion G, Prof, Riddell, Robert, Prof, Iverson, Erik R, MS, DeMets, David L, Prof

“…Summary Background Selective inhibition of cyclo-oxygenase-2 has been associated with an increased risk of cardiovascular events in several clinical trials…”
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Systematic review of preoperative and intraoperative colorectal Anastomotic Leak Prediction Scores (ALPS) by Venn, Mary L, Hooper, Richard L, Pampiglione, Tom, Morton, Dion G, Nepogodiev, Dmitri, Knowles, Charles H

“…ObjectiveTo systematically review preoperative and intraoperative Anastomotic Leak Prediction Scores (ALPS) and validation studies to evaluate performance and…”
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The impact of preoperative oral nutrition supplementation on outcomes in patients undergoing gastrointestinal surgery for cancer in low- and middle-income countries: a systematic review and meta-analysis by Knight, Stephen R., Qureshi, Ahmad U., Drake, Thomas M., Lapitan, Marie Carmela M., Maimbo, Mayaba, Yenli, Edwin, Tabiri, Stephen, Ghosh, Dhruva, Kingsley, Pamela A., Sundar, Sudha, Shaw, Catherine, Valparaiso, Apple P., Bhangu, Aneel, Brocklehurst, Peter, Magill, Laura, Morton, Dion G., Norrie, John, Roberts, Tracey E., Theodoratou, Evropi, Weiser, Thomas G., Burden, Sorrel, Harrison, Ewen M.

“…Malnutrition is an independent predictor for postoperative complications in low- and middle-income countries (LMICs). We systematically reviewed evidence on…”
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Computed tomographic colonography versus barium enema for diagnosis of colorectal cancer or large polyps in symptomatic patients (SIGGAR): a multicentre randomised trial by Halligan, Steve, Prof, Wooldrage, Kate, MSc, Dadswell, Edward, MSci, Kralj-Hans, Ines, PhD, von Wagner, Christian, PhD, Edwards, Rob, PhD, Yao, Guiqing, PhD, Kay, Clive, Prof, Burling, David, FRCR, Faiz, Omar, FRCS, Teare, Julian, FRCP, Lilford, Richard J, Prof, Morton, Dion, Prof, Wardle, Jane, Prof, Atkin, Wendy, Prof

“…Summary Background Barium enema (BE) is widely available for diagnosis of colorectal cancer despite concerns about its accuracy and acceptability. Computed…”
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Core Outcomes for Colorectal Cancer Surgery: A Consensus Study by McNair, Angus G K, Whistance, Robert N, Forsythe, Rachael O, Macefield, Rhiannon, Rees, Jonathan, Pullyblank, Anne M, Avery, Kerry N L, Brookes, Sara T, Thomas, Michael G, Sylvester, Paul A, Russell, Ann, Oliver, Alfred, Morton, Dion, Kennedy, Robin, Jayne, David G, Huxtable, Richard, Hackett, Roland, Dutton, Susan J, Coleman, Mark G, Card, Mia, Brown, Julia, Blazeby, Jane M

“…Colorectal cancer (CRC) is a major cause of worldwide morbidity and mortality. Surgical treatment is common, and there is a great need to improve the delivery…”
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In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer by Malla, Sudhir B, Fisher, David J, Domingo, Enric, Blake, Andrew, Hassanieh, Sylvana, Redmond, Keara L, Richman, Susan D, Youdell, Michael, Walker, Steven M, Logan, Gemma E, Chatzipli, Aikaterina, Amirkhah, Raheleh, Humphries, Matthew P, Craig, Stephanie G, McDermott, Ultan, Seymour, Matthew T, Morton, Dion G, Quirke, Philip, West, Nicholas P, Salto-Tellez, Manuel, Kennedy, Richard D, Johnston, Patrick G, Tomlinson, Ian, Koelzer, Viktor H, Campo, Letitia, Kaplan, Richard S, Longley, Daniel B, Lawler, Mark, Maughan, Timothy S, Brown, Louise C, Dunne, Philip D

“…The DNA damage immune response (DDIR) assay was developed in breast cancer based on biology associated with deficiencies in homologous recombination and…”
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Should surgical training include involvement in a clinical trial? by Morton, Dion, Bicknell, Colin D

“…The next generation of surgical consultants will need research experience to advance the specialty, writes Dion Morton, but Colin Bicknell worries about…”
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Discovery and Validation of Methylation Biomarkers for Ulcerative Colitis Associated Neoplasia by Beggs, Andrew D, James, Jonathan, Caldwell, Germaine, Prout, Toby, Dilworth, Mark P, Taniere, Phillipe, Iqbal, Tariq, Morton, Dion G, Matthews, Glenn

“…Abstract Background and aims Ulcerative colitis (UC) is associated with a higher background risk of dysplasia and/or neoplasia due to chronic inflammation…”
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