Search Results - "Diogo O. Souza"

Neural acetylcholinesterase and monoamine oxidase deregulation during streptozotocin-induced behavioral, metabolic and redox modification in Nauphoeta cinerea by Ogunsuyi, Opeyemi B, Olagoke, Olawande C, Famutimi, Mayokun E, Olatunde, Damilola M, Souza, Diogo O G, Oboh, Ganiyu, Barbosa, Nilda V, Rocha, João B T

“…Genetic and environmental factors have been linked with neurodegeneration, especially in the elderly. Yet, efforts to impede neurodegenerative processes have…”
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Glycolysis-Derived Compounds From Astrocytes That Modulate Synaptic Communication by Gonçalves, Carlos-Alberto, Rodrigues, Letícia, Bobermin, Larissa D, Zanotto, Caroline, Vizuete, Adriana, Quincozes-Santos, André, Souza, Diogo O, Leite, Marina C

“…Based on the concept of the tripartite synapse, we have reviewed the role of glucose-derived compounds in glycolytic pathways in astroglial cells. Glucose…”
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Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity by Dietrich, Marcelo O, Antunes, Catiele, Geliang, Gan, Liu, Zhong-Wu, Borok, Erzsebet, Nie, Yongzhan, Xu, Allison W, Souza, Diogo O, Gao, Qian, Diano, Sabrina, Gao, Xiao-Bing, Horvath, Tamas L

“…Sirt1 has been associated with various effects of calorie restriction, including an increase in lifespan. Here we show in mice that a central regulatory…”
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Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia by Espinosa, Janaína, Rocha, Andreia, Nunes, Fernanda, Costa, Marcelo S, Schein, Vanessa, Kazlauckas, Vanessa, Kalinine, Eduardo, Souza, Diogo O, Cunha, Rodrigo A, Porciúncula, Lisiane O

“…Intracerebroventricular (icv) streptozotocin (STZ) administration induces pathological and behavioral alterations similar to those observed in Alzheimer's…”
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JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats by Wong-Guerra, Maylin, Montano-Peguero, Yanay, Ramírez-Sánchez, Jeney, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Hernández-Enseñat, Daniela, Nonose, Yasmine, Valdés, Odalys, Mondelo-Rodriguez, Abel, Ortiz-Miranda, Yaquelin, Bergado, Gretchen, Carmenate, Tania, Soto del Valle, Roberto Menéndez, Pardo-Andreu, Gilberto, Outeiro, Tiago Fleming, Padrón-Yaquis, Alejandro Saúl, Martimbianco de Assis, Adriano, O Souza, Diogo, Nuñez-Figueredo, Yanier

“…•JM-20 improved different types of memory in a model of cognitive decline and neuronal damage in prefrontal cortex and hippocampus of adult…”
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Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects by Machado-Vieira, Rodrigo, Andreazza, Ana Cristina, Viale, Carlos Ivan, Zanatto, Vanessa, Cereser, Victor, Vargas, Rafael da Silva, Kapczinski, Flávio, Portela, Luiz V., Souza, Diogo O., Salvador, Mirian, Gentil, Valentim

“…Studies have proposed the involvement of oxidative stress and neuronal energy dysfunctions in the pathophysiology of bipolar disorder (BD). This study…”
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Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments by Rosemberg, Denis B, Rico, Eduardo P, Mussulini, Ben Hur M, Piato, Angelo L, Calcagnotto, Maria E, Bonan, Carla D, Dias, Renato D, Blaser, Rachel E, Souza, Diogo O, de Oliveira, Diogo L

“…The open tank paradigm, also known as novel tank diving test, is a protocol used to evaluate the zebrafish behavior. Several characteristics have been…”
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Effects of Single Low Dose of Dexamethasone before Noncardiac and Nonneurologic Surgery and General Anesthesia on Postoperative Cognitive Dysfunction-A Phase III Double Blind, Randomized Clinical Trial by Valentin, Livia Stocco Sanches, Pereira, Valeria Fontenelle Angelim, Pietrobon, Ricardo S, Schmidt, Andre P, Oses, Jean P, Portela, Luis V, Souza, Diogo O, Vissoci, João Ricardo Nickenig, Luz, Vinicius Fernando da, Trintoni, Leticia Maria de Araujo de Souza, Nielsen, Karen C, Carmona, Maria José Carvalho

“…Postoperative cognitive dysfunction (POCD) is a multifactorial adverse event most frequently in elderly patients. This study evaluated the effect of…”
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Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid β peptide in mice by Santos, Danúbia B., Peres, Kaite C., Ribeiro, Renata P., Colle, Dirleise, Santos, Alessandra A. dos, Moreira, Eduardo L.G., Souza, Diogo O.G., Figueiredo, Cláudia P., Farina, Marcelo

“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss and cognitive impairments. The presence of extracellular senile plaques…”
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Caffeine and an adenosine A₂A receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life by Cognato, Giana P, Agostinho, Paula M, Hockemeyer, Jörg, Müller, Christa E, Souza, Diogo O, Cunha, Rodrigo A

“…Seizures early in life cause long-term behavioral modifications, namely long-term memory deficits in experimental animals. Since caffeine and adenosine A₂A…”
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Differential proteomics of Zika virus (ZIKV) infection reveals molecular changes potentially involved in immune system evasion by a Brazilian strain of ZIKV by Tatara, Juliana M., Rosa, Rafael L., Varela, Ana Paula M., Teixeira, Tais F., Sesterheim, Patrícia, Gris, Anderson, Driemeier, David, Moraes, Amanda N. S., Berger, Markus, Peña, Ramon D., Roehe, Paulo M., Souza, Diogo O. G., Guimarães, Jorge A., Campos, Alexandre R., Santi, Lucélia, Beys-da-Silva, Walter O.

“…Zika virus (ZIKV) is an arbovirus that was responsible for multiple outbreaks from 2007 to 2015. It has been linked to cases of microcephaly in Brazil in 2015,…”
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Decreased Plasma Brain Derived Neurotrophic Factor Levels in Unmedicated Bipolar Patients During Manic Episode by Machado-Vieira, Rodrigo, Dietrich, Marcelo O, Leke, Renata, Cereser, Vitor H, Zanatto, Vanessa, Kapczinski, Flavio, Souza, Diogo O, Portela, Luis V, Gentil, Valentim

“…Background Bipolar disorder (BD) has been increasingly associated with abnormalities in neuroplasticity and cellular resilience. Brain Derived Neurotrophic…”
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Serum levels of S100B and NSE proteins in Alzheimer's disease patients by Chaves, Márcia L, Camozzato, Ana L, Ferreira, Eduardo D, Piazenski, Isabel, Kochhann, Renata, Dall'Igna, Oscar, Mazzini, Guilherme S, Souza, Diogo O, Portela, Luis V

“…Alzheimer's disease is the most common dementia in the elderly, and the potential of peripheral biochemical markers as complementary tools in the…”
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Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice by Botton, Paulo Henrique, Costa, Marcelo S., Ardais, Ana Paula, Mioranzza, Sabrina, Souza, Diogo O., da Rocha, João Batista Teixeira, Porciúncula, Lisiane O.

“…Caffeine is a psychostimulant with positive effects on cognition. Recent studies have suggested the participation of the cholinergic system in the effects of…”
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Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster by Abolaji, Amos O, Kamdem, Jean P, Lugokenski, Thiago H, Farombi, Ebenezer O, Souza, Diogo O, da Silva Loreto, Élgion L, Rocha, João B T

“…The compounds 4-vinylcyclohexene 1,2-monoepoxide (VCM) and 4-Vinylcyclohexene diepoxide (VCD) are the two downstream metabolites of 4-vinylcyclohexene (VCH),…”
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Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: A preliminary 4-week study by de Sousa, Rafael T., van de Bilt, Martinus T., Diniz, Breno S., Ladeira, Rodolfo B., Portela, Luis V., Souza, Diogo O., Forlenza, Orestes V., Gattaz, Wagner F., Machado-Vieira, Rodrigo

“…► This study investigates the effects of lithium monotherapy on BDNF in bipolar mania. ► BDNF levels increased significantly after 4 weeks of lithium…”
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Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model by Almeida, Roberto Farina, Nonose, Yasmine, Ganzella, Marcelo, Loureiro, Samanta Oliveira, Rocha, Andréia, Machado, Daniele Guilhermano, Bellaver, Bruna, Fontella, Fernanda Urruth, Leffa, Douglas T., Pettenuzzo, Letícia Ferreira, Venturin, Gianina Teribele, Greggio, Samuel, da Costa, Jaderson Costa, Zimmer, Eduardo R., Elisabetsky, Elaine, Souza, Diogo O.

“…Major depressive disorder (MDD) leads to pervasive changes in the health of afflicted patients. Despite advances in the understanding of MDD and its treatment,…”
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Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain by Stringari, James, Nunes, Adriana K.C., Franco, Jeferson L., Bohrer, Denise, Garcia, Solange C., Dafre, Alcir L., Milatovic, Dejan, Souza, Diogo O., Rocha, João B.T., Aschner, Michael, Farina, Marcelo

“…During the perinatal period, the central nervous system (CNS) is extremely sensitive to metals, including methylmercury (MeHg). Although the mechanism(s)…”
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Allopurinol attenuates postoperative pain and modulates the purinergic system in patients undergoing abdominal hysterectomy: a randomized controlled trial by Schmidt, André P., de Oliveira, Enderson D., Fagundes, Aécio C., Hansel, Gisele, Pedrini, Renata O., Valdameri, Aline, Martinelli, Eduarda S., Schmidt, Sérgio R. G., Andrade, Cristiano F., Lara, Diogo R., Souza, Diogo O.

“…Purpose Allopurinol is a potent inhibitor of the enzyme xanthine oxidase used primarily in the treatment of hyperuricemia and gout. The aim of this study was…”
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Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes by Yin, Zhaobao, Milatovic, Dejan, Aschner, Judy L, Syversen, Tore, Rocha, Joao B.T, Souza, Diogo O, Sidoryk, Marta, Albrecht, Jan, Aschner, Michael

“…Abstract The neurotoxicity of high levels of methylmercury (MeHg) is well established both in humans and experimental animals. Astrocytes accumulate MeHg and…”
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