Search Results - "Diofano, Federica"
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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
Published in Nature communications (28-07-2021)“…Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens, but pro- and anti-viral activities have been reported for…”
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CRISPR/Cas9-Mediated Constitutive Loss of VCP (Valosin-Containing Protein) Impairs Proteostasis and Leads to Defective Striated Muscle Structure and Function In Vivo
Published in International journal of molecular sciences (16-06-2022)“…Valosin-containing protein (VCP) acts as a key regulator of cellular protein homeostasis by coordinating protein turnover and quality control. Mutations in VCP…”
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Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency
Published in PLoS genetics (02-11-2020)“…Mutations in the molecular co-chaperone Bcl2-associated athanogene 3 (BAG3) are found to cause dilated cardiomyopathy (DCM), resulting in systolic dysfunction…”
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Strong attenuation of SARS-CoV-2 Omicron BA.1 and increased replication of the BA.5 subvariant in human cardiomyocytes
Published in Signal transduction and targeted therapy (25-12-2022)Get full text
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5
Genetics of Cardiovascular Disease: Fishing for Causality
Published in Frontiers in cardiovascular medicine (01-06-2018)“…Cardiovascular disease (CVD) is still the leading cause of death in all western world countries and genetic predisposition in combination with traditional risk…”
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Prospective randomized evaluation of transcutaneous carbon dioxide monitoring during complex electrophysiological procedures under deep sedation: the TRACES trial
Published in Clinical research in cardiology (07-11-2024)“…Abstract Background The field of interventional electrophysiology is rapidly growing. For safe and efficient procedures sedation is needed for patient comfort…”
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Comparative Efficacy of Cavotricuspid Isthmus Ablation in Sinus Rhythm Versus Typical Atrial Flutter
Published in Hearts (Basel, Switzerland) (27-10-2024)“…Background: Cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) is the most common atrial macro-reentrant tachycardia, characterized by a typical ECG…”
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Constitutive Store-Operated Ca(2+) Entry Leads to Enhanced Nitric Oxide Production and Proliferation in Infantile Hemangioma-Derived Endothelial Colony-Forming Cells
Published in Stem cells and development (15-02-2016)“…Clonal endothelial progenitor cells (EPCs) have been implicated in the aberrant vascular growth that features infantile hemangioma (IH), the most common benign…”
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