Search Results - "Diniz, Gabriela Placoná"

MicroRNA‐1 overexpression blunts cardiomyocyte hypertrophy elicited by thyroid hormone by Diniz, Gabriela Placoná, Lino, Caroline Antunes, Moreno, Camila Rodrigues, Senger, Nathalia, Barreto‐Chaves, Maria Luiza Morais

“…It is well‐known that increased thyroid hormone (TH) levels induce cardiomyocyte growth. MicroRNAs (miRNAs) have been identified as key players in…”
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High fat diet reduces the expression of miRNA‐29b in heart and increases susceptibility of myocardium to ischemia/reperfusion injury by Guedes, Elaine Castilho, da Silva, Ivson Bezerra, Lima, Vanessa Morais, Miranda, Juliane B., Albuquerque, Rudá P., Ferreira, Julio C. B., Barreto‐Chaves, Maria Luiza M., Diniz, Gabriela Placoná

“…Several studies have shown the role of microRNAs (miRNAs) in myocardial dysfunction in response to ischemia/reperfusion (I/R). In this study, we investigated…”
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Angiotensin-(1-7) reduces cardiac effects of thyroid hormone by GSK3Β/NFATc3 signaling pathway by Senger, Nathalia, Melo, Marcos Barrouin, Diniz, Gabriela Placoná, Campagnole-Santos, Maria José, Santos, Robson Augusto Souza, Barreto-Chaves, Maria Luiza M

“…Patients with hyperthyroidism exhibit increased risk of development and progression of cardiac diseases. The activation of the renin-angiotensin system (RAS)…”
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Cardiac hypertrophy that affects hyperthyroidism occurs independently of the NLRP3 inflammasome by Parletta, Aline Cristina, Cerri, Gabriela Cavazza, Gasparini, Claudia Ribeiro Borba, Panico, Karine, Vieira-Junior, Denival Nascimento, Zacarias-Rodrigues, Larissa Maria, Senger, Nathalia, de Almeida Silva, Amanda, Fevereiro, Marina, Diniz, Gabriela Placoná, Irigoyen, Maria Cláudia Costa, Barreto-Chaves, Maria Luiza Morais

“…Cardiac hypertrophy (CH) is an adaptive response to maintain cardiac function; however, persistent stress responses lead to contractile dysfunction and heart…”
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miRNA-208a and miRNA-208b are triggered in thyroid hormone-induced cardiac hypertrophy – Role of type 1 Angiotensin II receptor (AT1R) on miRNA-208a/α-MHC modulation by Diniz, Gabriela Placoná, Takano, Ana Paula, Barreto-Chaves, Maria Luiza Morais

“…•Like β-MHC, miR-208b is down-regulated in the hyperthyroid group.•Similarly to α-MHC, the miR-208a expression is increased in hyperthyroidism.•AT1R mediates…”
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Angiotensin type 1 receptor mediates thyroid hormone-induced cardiomyocyte hypertrophy through the Akt/GSK-3β/mTOR signaling pathway by Diniz, Gabriela Placoná, Carneiro-Ramos, Marcela Sorelli, Barreto-Chaves, Maria Luiza Morais

“…Several studies have implicated the renin angiotensin system in the cardiac hypertrophy induced by thyroid hormone. However, whether Angiotensin type 1…”
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Loss of microRNA-22 prevents high-fat diet induced dyslipidemia and increases energy expenditure without affecting cardiac hypertrophy by Diniz, Gabriela Placoná, Huang, Zhan-Peng, Liu, Jianming, Chen, Jinghai, Ding, Jian, Fonseca, Renata Inzinna, Barreto-Chaves, Maria Luiza, Donato, Jr, Jose, Hu, Xiaoyun, Wang, Da-Zhi

“…Obesity is associated with development of diverse diseases, including cardiovascular diseases and dyslipidemia. MiRNA-22 (miR-22) is a critical regulator of…”
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Beta‐arrestin 2 mediates cardiac hypertrophy induced by thyroid hormones via AT1R by Lino, Caroline Antunes, Bortoli Teixeira, Larissa, Capelupe Simões, Sarah, Oliveira Silva, Tábatha, Diniz, Gabriela Placoná, Costa‐Neto, Claudio Miguel, Barreto‐Chaves, Maria Luiza Morais

“…We have previously reported that angiotensin II receptor type 1 (AT1R) contributes to the hypertrophic effects of thyroid hormones (TH) in cardiac cells. Even…”
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MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets by Guedes, Elaine Castilho, França, Gustavo Starvaggi, Lino, Caroline Antunes, Koyama, Fernanda Christtanini, Moreira, Luana do Nascimento, Alexandre, Juliana Gomes, Barreto-Chaves, Maria Luiza M., Galante, Pedro Alexandre Favoretto, Diniz, Gabriela Placoná

“…Recent studies have revealed the involvement of microRNAs (miRNAs) in the control of cardiac hypertrophy and myocardial function. In addition, several reports…”
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Cardiac microRNA-133 is down-regulated in thyroid hormone-mediated cardiac hypertrophy partially via Type 1 Angiotensin II receptor by Diniz, Gabriela Placoná, Lino, Caroline Antunes, Guedes, Elaine Castilho, Nascimento Moreira, Luana do, Barreto-Chaves, Maria Luiza Morais

“…Elevated thyroid hormone (TH) levels induce cardiac hypertrophy partially via type 1 Angiotensin II receptor (AT1R). MicroRNAs (miRNAs) are key regulators of…”
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Thyroid Hormone Increases TGF-β1 in Cardiomyocytes Cultures Independently of Angiotensin II Type 1 and Type 2 Receptors by Diniz, Gabriela Placoná, Carneiro-Ramos, Marcela Sorelli, Barreto-Chaves, Maria Luiza Morais

“…TH-induced cardiac hypertrophy in vivo is accompanied by increased cardiac Transforming Growth Factor-β1 (TGF-β1) levels, which is mediated by Angiotensin II…”
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AMPK signaling pathway is rapidly activated by T3 and regulates the cardiomyocyte growth by Takano, Ana Paula Cremasco, Diniz, Gabriela Placoná, Barreto-Chaves, Maria Luiza Morais

“…•T3 rapidly activated AMPK and proteins related to the AMPK signaling pathway.•The activation of AMPK blunted thyroid hormone induced cardiomyocyte…”
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Hypo-and hyperthyroidism affect the ATP, ADP and AMP hydrolysis in rat hippocampal and cortical slices by Bruno, Alessandra Nejar, Diniz, Gabriela Placoná, Ricachenevsky, Felipe Klein, Pochmann, Daniela, Bonan, Carla Denise, Barreto-Chaves, Maria Luiza M., Sarkis, João José Freitas

“…The presence of severe neurological symptoms in thyroid diseases has highlighted the importance of thyroid hormones in the normal functioning of the mature…”
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Time course of hydrogen peroxide–thioredoxin balance and its influence on the intracellular signalling in myocardial infarction by Schenkel, Paulo Cavalheiro, Tavares, Angela Maria Vicente, Fernandes, Rafael Oliveira, Diniz, Gabriela Placoná, Ludke, Ana Raquel Lehenbauer, Ribeiro, Maria Flavia Marques, da Rosa Araujo, Alex Sander, Barreto‐Chaves, Maria Luiza, Belló‐Klein, Adriane

“…We investigated the myocardial thioredoxin‐1 and hydrogen peroxide concentrations and their association with some prosurvival and pro‐apoptotic proteins,…”
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Regulation of Skeletal Muscle by microRNAs by Diniz, Gabriela Placoná, Wang, Da-Zhi

“…MicroRNAs (miRNAs) are a class of small noncoding RNAs highly conserved across species. miRNAs regulate gene expression posttranscriptionally by base pairing…”
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Redox-sensitive prosurvival and proapoptotic protein expression in the myocardial remodeling post-infarction in rats by Schenkel, Paulo Cavalheiro, Tavares, Angela Maria Vicente, Fernandes, Rafael Oliveira, Diniz, Gabriela Placoná, Bertagnolli, Mariane, da Rosa Araujo, Alex Sander, Barreto-Chaves, Maria Luiza, Ribeiro, Maria Flavia Marques, Clausell, Nadine, Belló-Klein, Adriane

“…In this study, we investigated the oxidative stress influence in some prosurvival and proapoptotic proteins after myocardial infarction (MI). Male Wistar rats…”
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New insight into the mechanisms associated with the rapid effect of T3 on AT1R expression by Diniz, Gabriela Placoná, Takano, Ana Paula Cremasco, Bruneto, Erika, da Silva, Francemilson Goulart, Nunes, Maria Tereza, Barreto-Chaves, Maria Luiza Morais

“…The angiotensin II type 1 receptor (AT1R) is involved in the development of cardiac hypertrophy promoted by thyroid hormone. Recently, we demonstrated that…”
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Genomic-independent action of thyroid hormones on NTPDase activities in Sertoli cell cultures from congenital hypothyroid rats by Zamoner, Ariane, Bruno, Alessandra Nejar, Casali, Emerson André, Corbelini, Patrícia Frasson, Diniz, Gabriela Placoná, Barreto-Chaves, Maria Luiza Morais, Silva, Fátima Regina Mena Barreto, Sarkis, João José Freitas, Pessoa-Pureur, Regina

“…The Sertoli cells play an essential role in the maintenance and control of spermatogenesis. The ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) and…”
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Deletion of miRNA-22 Induces Cardiac Hypertrophy in Females but Attenuates Obesogenic Diet-Mediated Metabolic Disorders by de Oliveira Silva, Tábatha, Lino, Caroline A., Buzatto, Vanessa C., Fontes Asprino, Paula, Lu, Yao Wei, Lima, Vanessa M., Fonseca, Renata I. B., Jensen, Leonardo, Murata, Gilson M., Filho, Sidney V., Ribeiro, Márcio A. C., Donato Jr, Jose, Ferreira, Julio C. B., Rodrigues, Alice C., Irigoyen, Maria Cláudia, Barreto-Chaves, Maria Luiza M., Huang, Zhan-Peng, Favoretto Galante, Pedro A., Wang, Da-Zhi, Diniz, Gabriela P.

“…Background/Aims: Obesity is a risk factor associated with cardiometabolic complications. Recently, we reported that miRNA-22 deletion attenuated high-fat…”
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miRNA‐21 and miRNA‐133b are decreased in hyperthyroidism‐induced cardiac hypertrophy – Critical role of Type 1 Angiotensin II receptor (AT1R) by Diniz, Gabriela Placoná, Takano, Ana Paula C, Barreto‐Chaves, Maria Luiza Morais

“…Abstract only Objective To investigate the miRNA‐21 and miRNA‐133b levels in T4‐induced cardiac hypertrophy, as well as the potential influence exerted by AT1R…”
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