Search Results - "Dinh, Chuong T"
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Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2013)“…Topical preexposure prophylaxis interrupts HIV transmission at the site of mucosal exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse…”
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Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures
Published in PloS one (08-06-2016)“…Topical preexposure prophylaxis (PrEP) against HIV has been marginally successful in recent clinical trials with low adherence rates being a primary factor for…”
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Tenofovir Disoproxil Fumarate Intravaginal Ring Protects High-Dose Depot Medroxyprogesterone Acetate–Treated Macaques From Multiple SHIV Exposures
Published in Journal of acquired immune deficiency syndromes (1999) (01-01-2015)“…Preclinical HIV prevention models use either a single high-dose viral challenge in depot medroxyprogesterone acetate–treated macaques or repeated viral…”
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Pharmacokinetics and preliminary safety study of pod-intravaginal rings delivering antiretroviral combinations for HIV prophylaxis in a macaque model
Published in Antimicrobial agents and chemotherapy (01-09-2014)“…Preexposure prophylaxis using oral regimens involving the HIV nucleoside reverse transcriptase inhibitors tenofovir disoproxil fumarate (TDF) and emtricitabine…”
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Repeated administration of high‐dose depot medroxyprogesterone acetate does not alter SHIVSF162p3 viral kinetics and tenofovir pharmacokinetics when delivered via intravaginal rings
Published in Journal of medical primatology (01-08-2017)“…Background Intravaginal rings (IVR) for HIV prevention will likely be used by women on depot medroxyprogesterone acetate (DMPA) hormonal contraception. We used…”
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Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques
Published in Drug delivery and translational research (01-10-2018)“…This study evaluated effects of differing gel volumes on pharmacokinetics (PK). IQB4012, a gel containing the non-nucleoside reverse transcriptase inhibitor…”
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Repeated administration of high-dose depot medroxyprogesterone acetate does not alter SHIV SF 162p3 viral kinetics and tenofovir pharmacokinetics when delivered via intravaginal rings
Published in Journal of medical primatology (01-08-2017)“…Intravaginal rings (IVR) for HIV prevention will likely be used by women on depot medroxyprogesterone acetate (DMPA) hormonal contraception. We used pigtailed…”
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