Search Results - "Dingwell, Luke S."
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Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation
Published in American journal of transplantation (01-03-2018)“…Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft preservation and functional improvement in kidney transplantation. We…”
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GDF5 deficiency prevents cardiac rupture following acute myocardial infarction in mice
Published in Cardiovascular pathology (01-01-2024)“…We previously showed that growth differentiation factor 5 (GDF5) limits infarct expansion post-myocardial infarction (MI). We now examine the acute post-MI…”
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Continuous Normothermic Ex Vivo Kidney Perfusion Improves Graft Function in Donation After Circulatory Death Pig Kidney Transplantation
Published in Transplantation (01-04-2017)“…BACKGROUNDDonation after circulatory death (DCD) is current clinical practice to increase the donor pool. Deleterious effects on renal graft function are…”
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B-Cell Deficiency Lowers Blood Pressure in Mice
Published in Hypertension (Dallas, Tex. 1979) (01-03-2019)“…The proto-oncogene c-myb (and corresponding nuclear transcription factor, c-Myb) regulates the proliferation and differentiation of hematologic and vascular…”
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Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis
Published in Diabetes & vascular disease research (01-05-2021)“…Background: Insulin exerts vasculoprotective effects on endothelial cells (ECs) and growth-promoting effects on vascular smooth muscle cells (SMCs) in vitro,…”
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Abstract 11704: NF-κβ Signaling Regulates Vasopressin Receptor 2 Promoter Activity
Published in Circulation (New York, N.Y.) (16-11-2021)“…BackgroundArginine vasopressin, through vasopressin receptor 2 (AVP-V2R), regulates water reabsorption via aquaporin-2 and sodium reabsorption via several…”
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453-P: Cell-Specific Role of Insulin in an In Vivo Model of Restenosis
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The effects of insulin on the vasculature remains a hotly debated and controversial topic. Its role on endothelial cells (ECs) is thought to be…”
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Abstract 10884: B-Cell-Mediated Sodium and Water Retention Contributes to Heart Failure Pathogenesis
Published in Circulation (New York, N.Y.) (16-11-2021)“…BackgroundB-cells have been shown to serve pathogenic roles in heart failure through cardiac-specific monocyte mobilization and autoantibody deposition. Beyond…”
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The Requirement of B-cells for Renal and Blood Pressure Homeostasis
Published in Atherosclerosis. Supplements (01-06-2018)Get full text
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