Search Results - "Dingledine, R"

Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus by Serrano, G E, Lelutiu, N, Rojas, A, Cochi, S, Shaw, R, Makinson, C D, Wang, D, FitzGerald, G A, Dingledine, R

“…Cyclooxygenase-2 (COX-2), a source of inflammatory mediators and a multifunctional neuronal modulator, is rapidly induced in select populations of cortical…”
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Mixminion: design of a type III anonymous remailer protocol by Danezis, G., Dingledine, R., Mathewson, N.

“…We present Mixminion, a message-based anonymous remailer protocol with secure single-use reply blocks. Mix nodes cannot distinguish Mixminion forward messages…”
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Degeneration and proliferation of astrocytes in the mouse dentate gyrus after pilocarpine-induced status epilepticus by Borges, Karin, McDermott, Dayna, Irier, Hasan, Smith, Yoland, Dingledine, Raymond

“…Astrocytes are relatively resistant to injury compared to neurons and oligodendrocytes. Here, we report transient region-specific loss of astrocytes in mice…”
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Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins by Washburn, M S, Dingledine, R

“…A variety of polyamine spider and wasp toxins are known to block N-methyl-D-aspartate receptor channels and recombinant…”
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AMPA receptors: molecular and functional diversity by Borges, K, Dingledine, R

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Functional interactions between cannabinoid and metabotropic glutamate receptors in the central nervous system by Doherty, James, Dingledine, Raymond

“…The recent appreciation that two G-protein-coupled receptors, metabotropic glutamate and cannabinoid, are trans-synaptically linked by a small lipid messenger…”
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Complex effects of CNQX on CA1 interneurons of the developing rat hippocampus by Maccaferri, G., Dingledine, R.

“…We have investigated the effect of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, 6-cyano-7-nitro-quinoxaline-2,3-dione…”
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Heterogeneity of synaptic glutamate receptors on CA3 stratum radiatum interneurones of rat hippocampus by McBain, C J, Dingledine, R

“…1. Whole-cell recordings were made from interneurons located within CA3 stratum radiatum of neonate rat hippocampal slices. All experiments were performed in…”
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Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism by Greene, J.G, Greenamyre, J.T, Dingledine, R

“…Abstract Many mechanisms of neurodegeneration have been implicated in Parkinson’s disease, but which ones are most important and potential interactions among…”
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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition by Mott, David D, Doherty, James J, Zhang, Sunan, Washburn, Mark S, Fendley, Morris J, Lyuboslavsky, Polina, Traynelis, Stephen F, Dingledine, Raymond

“…The phenylethanolamines, ifenprodil and CP-101,606, are NMDA receptor antagonists with promising neuroprotective properties. In recombinant NMDA receptors…”
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Future directions for epilepsy research by JACOBS, M. P, FISCHBACH, G. D, THEODORE, W. H, DAVIS, M. R, DICHTER, M. A, DINGLEDINE, R, LOWENSTEIN, D. H, MORRELL, M. J, NOEBELS, J. L, ROGAWSKI, M. A, SPENCER, S. S

“…The authors propose that epilepsy research embark on a revitalized effort to move from targeting control of symptoms to strategies for prevention and cure. The…”
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Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice by Traynelis, S F, Dingledine, R

“…1. The CA1 region of rat hippocampal slices bathed in 8.5 mM interstitial K+ ([K+]o) exhibited spontaneous 20- to 90-s electrographic seizures at regular…”
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N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cells by Dingledine, R

“…The depolarizing actions of N-methyl-DL-aspartate (NMA) and L-glutamate on pyramidal neurones were compared in a hippocampal slice preparation. Tetrodotoxin (1…”
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Synaptic input from CA3 pyramidal cells to dentate basket cells in rat hippocampus by Kneisler, T B, Dingledine, R

“…1. Excitatory inputs from CA3 pyramidal cells to dentate basket cells were examined using the whole-cell recording technique in neonatal (10-16 days) rat…”
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Text Mining Biomedical Literature for Discovering Gene-to-Gene Relationships: A Comparative Study of Algorithms by Ying Liu, Navathe, S.B., Civera, J., Dasigi, V., Ram, A., Ciliax, B.J., Dingledine, R.

“…Partitioning closely related genes into clusters has become an important element of practically all statistical analyses of microarray data. A number of…”
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Subunit-Dependent Modulation of Kainate Receptors by Extracellular Protons and Polyamines by Mott, David D, Washburn, Mark S, Zhang, Sunan, Dingledine, Raymond J

“…Synaptic activity causes significant fluctuations in proton concentrations in the brain. Changes in pH can affect neuronal excitability by acting on…”
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Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons by McBain, C, Dingledine, R

“…1. Spontaneous miniature synaptic events were studied with tight-seal whole-cell recordings from CA3 neurons maintained in the hippocampal slice from immature…”
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Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice by Dingledine, R, Hynes, M A, King, G L

“…The effects of the N-methyl-D-aspartate (NMDA) receptor antagonist, D-2-amino-5-phosphonovaleric acid (D-APV), and other excitatory amino acid antagonists,…”
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Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures by Traynelis, S F, Dingledine, R

“…1. Focal electrographic seizures arose in the CA1 region of rat hippocampal slices bathed in elevated (8.5 mM) external potassium [( K+]o). High [K+]o also…”
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Neurological Disease: Listening to Gene Silencers by Roopra, A, Huang, Y, Dingledine, R

“…Neurons regulate the expression of genes essential to individual neuron function through elegant combinatorial interactions among a limited number of…”
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